scholarly journals Longitudinal associations between depression and substance dependence from adolescence through early adulthood

2010 ◽  
Vol 107 (2-3) ◽  
pp. 154-160 ◽  
Author(s):  
Naomi R. Marmorstein ◽  
William G. Iacono ◽  
Stephen M. Malone
PEDIATRICS ◽  
2021 ◽  
pp. e2020036657
Author(s):  
Bezawit E. Kase ◽  
Nanda Rommelse ◽  
Qi Chen ◽  
Lin Li ◽  
Anneli Andersson ◽  
...  

2017 ◽  
Vol 32 (4) ◽  
pp. 728-753 ◽  
Author(s):  
Courtenay Sprague ◽  
Bharathi Radhakrishnan ◽  
Shelley Brown ◽  
Theresa Sommers ◽  
David W. Pantalone

Justice-involved HIV-positive women, particularly those in the U.S. South, are a hidden, understudied population. Little work has explored their psychosocial histories in relation to their HIV risk. We conducted a content analysis of their life history narratives from childhood to present, via in-depth interviews with 24 such women in 2 Alabama cities. Findings included the following: (a) In childhood/adolescence, consistent HIV risk factors were present, beginning with early sexual abuse and induction into alcohol/substance use; (b) By early adulthood, HIV and incarceration risks were compounded in social settings, through cyclical substance use, revictimization, and reoffending; (c) In later adulthood, HIV risk behaviors were perpetuated for decades, as participants coped with un- or undertreated abuse/trauma sequelae, through substance dependence, and reoffending.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
David Mongan ◽  
Colm Healy ◽  
Hannah J. Jones ◽  
Stan Zammit ◽  
Mary Cannon ◽  
...  

AbstractPolyunsaturated fatty acids (PUFAs) may be pertinent to the development of mental disorders, for example via modulation of inflammation and synaptogenesis. We wished to examine cross-sectional and longitudinal associations between PUFAs and mental disorders in a large cohort of young people. Participants in the Avon Longitudinal Study of Parents and Children were interviewed and provided blood samples at two sampling periods when approximately 17 and 24 years old. Plasma PUFA measures (total omega-6 [n-6], total omega-3 [n-3], n-6:n-3 ratio and docosahexaenoic acid [DHA] percentage of total fatty acids) were assessed using nuclear magnetic resonance spectroscopy. Cross-sectional and longitudinal associations between standardised PUFA measures and three mental disorders (psychotic disorder, moderate/severe depressive disorder and generalised anxiety disorder [GAD]) were measured by logistic regression, adjusting for age, sex, body mass index and cigarette smoking. There was little evidence of cross-sectional associations between PUFA measures and mental disorders at age 17. At age 24, the n-6:n-3 ratio was positively associated with psychotic disorder, depressive disorder and GAD, while DHA was inversely associated with psychotic disorder. In longitudinal analyses, there was evidence of an inverse association between DHA at age 17 and incident psychotic disorder at age 24 (adjusted odds ratio 0.44, 95% confidence interval 0.22–0.87) with little such evidence for depressive disorder or GAD. There was little evidence for associations between change in PUFA measures from 17 to 24 years and incident mental disorders at 24 years. These findings provide support for associations between PUFAs and mental disorders in early adulthood, and in particular, for DHA in adolescence in relation to prevention of psychosis.


2014 ◽  
Vol 28 (1) ◽  
pp. 238-246 ◽  
Author(s):  
Jessie L. Breyer ◽  
Susanne Lee ◽  
Ken C. Winters ◽  
Gerald J. August ◽  
George M. Realmuto

2010 ◽  
Vol 74 (6) ◽  
pp. 390-398 ◽  
Author(s):  
Katharina Diethelm ◽  
Lars Libuda ◽  
Katja Bolzenius ◽  
Barbara Griefahn ◽  
Anette E. Buyken ◽  
...  

Author(s):  
Lara MC Puhlmann ◽  
Mélodie Derome ◽  
Larisa Morosan ◽  
Deniz Kilicel ◽  
Pascal Vrtička ◽  
...  

2014 ◽  
Vol 11 (4) ◽  
pp. 784-789 ◽  
Author(s):  
Renata Moraes Bielemann ◽  
Virgílio Viana Ramires ◽  
Denise Petrucci Gigante ◽  
Pedro Curi Hallal ◽  
Bernardo Lessa Horta

Background:The purpose of this study was to evaluate cross-sectional and longitudinal associations between physical activity and triglyceride and HDLc levels in young male adults.Methods:We used information about males belonging 1982 Pelotas Birth Cohort. Physical activity in 4 domains (leisure time, transportation, household, and occupation) was assessed by self-report in participants of the cohort at ages of 18 and 23 years. Subjects were active if reached the recommendation of 150 min/week of moderate to vigorous physical activity. At 23 years of age, blood sample was collected, and triglycerides and HDLc levels estimated. Multivariate linear and Poisson regression were used to adjust the estimates for confounders.Results:Males who were inactive at 18 and active at 23 years had 41% lower risk (β = 0.59; 95% confidence interval: 0.40; 0.89) for borderline-high triglycerides (≥ 150 mg/dL) as compared with those who were inactive at both follow-ups. No association was found between changes of physical activity and HDLc level. In cross-sectional analyses, greater HDLc levels were found in active subjects in 4 domains, whereas there was no difference in HDL levels according physical activity during leisure time.Conclusion:Becoming active from adolescence to early adulthood reduced the risk for high triglycerides. Current physical activity was associated with greater HDLc levels.


2019 ◽  
Vol 4 (4) ◽  
pp. 633-640 ◽  
Author(s):  
Canice E. Crerand ◽  
Ari N. Rabkin

Purpose This article reviews the psychosocial risks associated with 22q11.2 deletion syndrome, a relatively common genetic condition associated with a range of physical and psychiatric problems. Risks associated with developmental stages from infancy through adolescence and early adulthood are described, including developmental, learning, and intellectual disabilities as well as psychiatric disorders including anxiety, mood, and psychotic disorders. Other risks related to coping with health problems and related treatments are also detailed for both affected individuals and their families. Conclusion The article ends with strategies for addressing psychosocial risks including provision of condition-specific education, enhancement of social support, routine assessment of cognitive abilities, regular mental health screening, and referrals for empirically supported psychiatric and psychological treatments.


Sign in / Sign up

Export Citation Format

Share Document