Risk of gestational diabetes mellitus by pre-pregnancy body mass index: A systematic review and meta-analysis

Author(s):  
Farid Najafi ◽  
Jalil Hasani ◽  
Neda Izadi ◽  
Seyed-Saeed Hashemi-Nazari ◽  
Zahra Namvar ◽  
...  
2019 ◽  
Vol 25 (3-4) ◽  
pp. 74-79 ◽  
Author(s):  
Sumanta Saha ◽  
Sujata Saha

<b><i>Aims:</i></b> To date, it is largely unknown how body mass index (BMI), gestational weight (GW), and stored vitamin D (25(OH)D) levels change in the vitamin D-supplemented gestational diabetes mellitus (GDM) patients, irrespective of their pre-pregnancy BMI. Therefore, to study this association, a prospective systematic review and meta-analysis protocol is proposed here. <b><i>Methods:</i></b> Primarily, different databases (PubMed, Embase and Scopus) will be searched (without any limitation to date or language) for randomised parallel-arm trials comparing GW, BMI and stored vitamin D level in the body among GDM patients who were supplemented and not supplemented with vitamin D, besides their conventional GDM care. The study selection process and the consecutive risk of bias assessment will adhere to the PRISMA 2009 flow chart and the Cochrane collaboration’s guideline, respectively. These interventions’ effect on the respective outcomes will be compared by meta-analysis (along with an assessment of the statistical heterogeneity) when comparable data will be available from at least 4 studies. Subgroup analysis and Egger’s meta-regression will follow if an adequate number of trials are available. Narrative reporting will be considered when a quantitative comparison is not feasible for any of the outcomes. <b><i>Conclusion:</i></b> The proposed review aims to compare the BMI, GW, and 25(OH)D levels in the blood between the vitamin D supplemented and not supplemented GDM patients.


2018 ◽  
Vol 20 (3) ◽  
pp. 472-486 ◽  
Author(s):  
Farid Najafi ◽  
Jalil Hasani ◽  
Neda Izadi ◽  
Seyed‐Saeed Hashemi‐Nazari ◽  
Zahra Namvar ◽  
...  

2015 ◽  
Vol 64 (5) ◽  
pp. 87-95 ◽  
Author(s):  
Roman Victorovich Kapustin ◽  
Ol’ga Nikolaevna Arzhanova ◽  
Olesya Nikolaevna Bespalova ◽  
Vladimir Stepanovich Pakin ◽  
Andrey Gennadievich Kiselev

Objective: on the basis of a systematic review, clarify the role of overweight and obesity as a predictor of gestational diabetes mellitus (GDM). Materials and methods: an analysis of the literature data of the leading bibliographic sources - MEDLINE, Cochrane col., EMBASE. To evaluate the body mass index and standards of weight gain during pregnancy used the WHO guidelines and criteria of the Institute of Medicine (2009). The frequency and the odds ratio (OR) of developing GDM was estimated separately for each of the three groups in BMI. Results: A systematic review included 23 different design studies involving 740 510 women. It was found that the odds ratio of the risk of GDM in a group of pregnant women with excess weight is doubled - 2.22 (95 % CI 1.72 - 3.64), and almost four in obesity - 3.88 (95 % CI 2.97 - 5.32). The incidence of GDM in a group of pregnant women with normal body mass index - 3.77 % in the group with excess body weight - 6.59 %, in the group with obesity - 9.88 %. Conclusions: The obtained strong evidence of a direct connection between the linear increase in maternal BMI and the risk of developing gestational diabetes. Pregnant women with excess weight and obesity are at high risk for carbohydrate disorders during pregnancy.


2018 ◽  
Author(s):  
George Simeakis ◽  
Evangelia Vogiatzi ◽  
Panagiota Konstantakou ◽  
Evangelia Zapanti ◽  
Katerina Saltiki ◽  
...  

2019 ◽  
Author(s):  
Jose Alberto Martínez-Hortelano ◽  
Ivan Cavero Redondo ◽  
Celia Alvarez ◽  
Ana Díez-Fernández ◽  
Montserrat Hernández-Luengo ◽  
...  

2021 ◽  
Vol 38 ◽  
pp. 101016
Author(s):  
Gayathri Delanerolle ◽  
Peter Phiri ◽  
Yutian Zeng ◽  
Kathleen Marston ◽  
Nicola Tempest ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
pp. 218
Author(s):  
Sambit Das ◽  
Mahesh Rath ◽  
Lipsa Das ◽  
Kasturi Bharadwaj

Background: Gestational Diabetes Mellitus (GDM) is usually diagnosed between 24th and 28th gestational week using the 75-g Oral Glucose Tolerance Test (OGTT). It is controversial that if FPG ≥92 mg/dL before 24th gestational week should be intervened or not. The aim of this study was to evaluate the value of FPG to screen GDM before 24th gestational week in women with different pre-pregnancy Body Mass Index (BMI).Methods: This was a hospital based retrospective cohort study done at CHC Balipatna, Khurdha, Odisha. Women who had a singleton live birth between June 20, 2016 and June 30, 2019, resided in Balipatna block area and received prenatal care in the Community Health Centre, were included in this study. Pre-pregnancy BMI, FPG before the 24th gestational week, and one-step GDM screening with 75 g-OGTT at the 24th to 28th gestational weeks were extracted from medical records and analyzed. The pregnant women were classified into four groups based on pre-pregnancy BMI: Group A (underweight), Group B (normal), Group C (overweight) and Group D (obesity). Statistical analysis using independent sample t-test, Analysis of Variance (ANOVA) and Pearson Chi-square test was done.Results: The prevalence of GDM was 20.0% (68/341) in the study population. FPG decreased gradually as the gestational age increased in all pre-pregnancy BMI groups until the 19th gestational week. The incidence of GDM in women with FPG ≥92 mg/dL in the 19th to 24th gestational weeks and pre-pregnancy overweight or obesity was significantly higher than that in women with FPG ≥92 mg/dL and pre-pregnancy BMI <24.0 kg/m2.Conclusions: FPG decreased gradually as the gestational age increased in all pre-pregnancy BMI groups until the 19th gestational week. Pre-pregnancy overweight or obesity was associated with an increased FPG value before the 24th gestational week. FPG ≥92 mg/dL between 19 and 24 gestational weeks should be treated as GDM in women with pre-pregnancy overweight and obesity.


Sign in / Sign up

Export Citation Format

Share Document