Antiphospholipid antibodies and neurological manifestations in acute COVID-19: A single-centre cross-sectional study

Objective: To evaluate abdominal versus vaginal hysterectomy in relation to operative and post operative complications.Design: Single centre cross sectional study. Place and duration: The Department of Obstetric and Gynaecology, Shaikh Zayed post graduateMedical institute and Hospital, Lahore from 1 November 2005 to 31 October 2006. Subject and methods: All the patients with benign st stindications for hysterectomy (abdominal and vaginal) were included except patients with serious / complicated medical disease. Relativeinformations were filled in a Performa and informations were taken from case records. Results: This audit report included 200 women. 23.3%patients of vaginal hysterectomy were in the age group of 40-45 years while 35.7%patients of abdominal hysterectomy were in the age of 51-55years. Main indication for abdominal hysterectomy (85.5%) was fibroid uterus while for vaginal hysterectomy (66.6%) was Uterovaginal prolapse.Most common immediate post operative complication in abdominal and vaginal hysterectomy was fever in 42.8% and 20.0% respectively.Intraoperative visceral injuries were done in 4 patients in abdominal hysterectomy while no injury was done in vaginal hysterectomy. 44(80%)patients of vaginal hysterectomy were discharged with in 7 days of hospitalization while 64 (44%) patients of abdominal hysterectomy weredischarged with in 7 days of hospitalization. Conclusion: Hysterectomy either abdominal or vaginal is very safe and there were no lethalcomplication except few minor complications and also there was no mortality.

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Prevalence of hypothyroidism in chronic kidney disease: a single centre cross-sectional study

International Journal of Health Research and Medico Legal Practice ◽

10.31741/ijhrmlp.v5.i1.2019.4 ◽

2019 ◽

Vol 5 (1) ◽

pp. 4

Author(s):

Mahanta PJ ◽

Agarwalla Bishal ◽

Sharma Manjuri

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Cross Sectional Study ◽

Sectional Study ◽

Single Centre ◽

Cross Sectional

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Neurological manifestations of dengue: A cross sectional study

Travel Medicine and Infectious Disease ◽

10.1016/j.tmaid.2013.11.001 ◽

2014 ◽

Vol 12 (2) ◽

pp. 189-193 ◽

Cited By ~ 17

Author(s):

Praveen Nilendra Weeratunga ◽

Manjula Chandragomi Caldera ◽

Inuka Kishara Gooneratne ◽

Ranjanie Gamage ◽

Priyankara Perera

Keyword(s):

Cross Sectional Study ◽

Neurological Manifestations ◽

Sectional Study ◽

Cross Sectional

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Prevalence of potentially inappropriate medications at admission and discharge among hospitalised elderly patients with acute medical illness at a single centre in Japan: a retrospective cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2017-021152 ◽

2018 ◽

Vol 8 (7) ◽

pp. e021152 ◽

Cited By ~ 14

Author(s):

Junpei Komagamine

Keyword(s):

Elderly Patients ◽

Cross Sectional Study ◽

Medical Illness ◽

Potentially Inappropriate Medications ◽

Sectional Study ◽

Single Centre ◽

Cross Sectional ◽

Coronary Syndrome ◽

Hospitalised Patients ◽

Inappropriate Medications

ObjectiveTo determine the prevalence of potentially inappropriate medications (PIMs) at admission and discharge among hospitalised elderly patients with acute medical illness in Japan.DesignA retrospective single-centre cross-sectional study.ParticipantsHospitalised patients aged 65 years or older admitted for pneumonia, heart failure, ischaemic stroke, acute coronary syndrome, chronic obstructive pulmonary disease or asthma, gastrointestinal bleeding, urinary tract infection or epilepsy from September 2014 to June 2016 who were still alive at discharge.Main outcome measuresThe primary outcome was the proportion of patients taking at least one PIM at admission and discharge. PIMs were defined based on the 2015 American Geriatric Society Beers Criteria. Temporal changes in the proportion of patients taking at least one PIM from admission to discharge were also evaluated.ResultsDuring the study period, 689 eligible patients were identified. The median patient age was 82.0 years (IQR 76.0–88.0), 348 (50.5%) were men and the median number of medications at admission was 5.0 (IQR 3.0–8.0). The proportions of patients taking any PIMs at admission and discharge were 47.9% (95% CI 44.2% to 51.6%) and 25.1% (95% CI 21.9% to 28.4%), respectively. The proportion of patients taking any PIMs was significantly lower at discharge than at admission (reduction rate 0.48, 95%, CI 0.41 to 0.53).ConclusionsA substantial proportion of hospitalised elderly patients with acute medical illness took PIMs at admission and discharge. These findings should be confirmed at other hospitals in Japan.

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Patients with Essential Thrombocythaemia have an Increased Prevalence of Antiphospholipid Antibodies which may be associated with Thrombosis

Thrombosis and Haemostasis ◽

10.1055/s-0037-1613087 ◽

2002 ◽

Vol 87 (05) ◽

pp. 802-807 ◽

Cited By ~ 36

Author(s):

S. Donohoe ◽

P. Carr ◽

M. Dave ◽

I. Mackie ◽

S.J. Machin ◽

...

Keyword(s):

Relative Risk ◽

Antiphospholipid Antibodies ◽

Significant Proportion ◽

Cross Sectional Study ◽

Essential Thrombocythaemia ◽

Sectional Study ◽

Cross Sectional ◽

Thrombotic Risk ◽

Glycoprotein I ◽

Thrombotic Complications

SummaryA significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life. We performed a retrospective cross sectional study of the prevalence of antiphospholipid antibodies (APA) in 68 ET patients. Compared to 200 “elderly” controls (> 50 years) there was a significant increase in anticardiolipin IgM (p < 0.0001) and anti β2 glycoprotein I (anti-β2GPI) IgM (p < 0.0001) antibodies in ET. Thrombosis occurred in 10/20 with APA and 12/48 without, p = 0.04, relative risk 2.0 (95% confidence intervals 1.03–3.86); these patients did not differ in terms of other clinical features. The prevalence of thrombosis in patients with dual APA (6/7) was significant when compared to those with single APA (p = 0.02) and the remaining patients (p < 0.0002). Also anti-β2GP1 IgM antibodies either alone, or in combination with another APA, were associated with thrombosis (p = 0.02). These results suggest that the prevalence of APA in ET and their influence upon thrombotic risk merit investigation in a larger study.

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