scholarly journals Patients with Essential Thrombocythaemia have an Increased Prevalence of Antiphospholipid Antibodies which may be associated with Thrombosis

2002 ◽  
Vol 87 (05) ◽  
pp. 802-807 ◽  
Author(s):  
S. Donohoe ◽  
P. Carr ◽  
M. Dave ◽  
I. Mackie ◽  
S.J. Machin ◽  
...  

SummaryA significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life. We performed a retrospective cross sectional study of the prevalence of antiphospholipid antibodies (APA) in 68 ET patients. Compared to 200 “elderly” controls (> 50 years) there was a significant increase in anticardiolipin IgM (p < 0.0001) and anti β2 glycoprotein I (anti-β2GPI) IgM (p < 0.0001) antibodies in ET. Thrombosis occurred in 10/20 with APA and 12/48 without, p = 0.04, relative risk 2.0 (95% confidence intervals 1.03–3.86); these patients did not differ in terms of other clinical features. The prevalence of thrombosis in patients with dual APA (6/7) was significant when compared to those with single APA (p = 0.02) and the remaining patients (p < 0.0002). Also anti-β2GP1 IgM antibodies either alone, or in combination with another APA, were associated with thrombosis (p = 0.02). These results suggest that the prevalence of APA in ET and their influence upon thrombotic risk merit investigation in a larger study.

2021 ◽  
pp. 101070
Author(s):  
Laura A. Benjamin ◽  
Ross W. Paterson ◽  
Rachel Moll ◽  
Charis Pericleous ◽  
Rachel Brown ◽  
...  

2005 ◽  
Vol 186 (5) ◽  
pp. 442-443 ◽  
Author(s):  
Luis R. Patino ◽  
Jean-Paul Selten ◽  
Herman van Engeland ◽  
Jan H. M. Duyx ◽  
René S. Kahn ◽  
...  

SummaryA cross-sectional study of 3426 referred children and adolescents showed that the presence of both migration history and family dysfunction was associated with a fourfold (95% CI 2–9) higher risk of psychotic symptoms compared with the absence of these factors. The relative risk was 2 (95% CI 1–4) for migration history only. Interaction between migration history and family dysfunction accounted for 58% (95% CI 5–91%) of those with psychotic symptoms. These results suggest a relationship between family dysfunction and migration in the development of psychosis.


1994 ◽  
Vol 220 (4) ◽  
pp. 544-551 ◽  
Author(s):  
Lloyd M. Taylor ◽  
Richard W. Chitwood ◽  
Ronald L. Dalman ◽  
Gary Sexton ◽  
Scott H. Goodnight ◽  
...  

2021 ◽  
Author(s):  
Yousef Khader ◽  
Ahmad Bawaneh ◽  
Zaid Al-Hamdan

BACKGROUND The Syrian conflict started in 2011 and resulted ever since in a large displacement of Syrians. Conflict-related violence coupled with displacement related stressors such as poverty, poor access to health services, loss of family support and discrimination had a significant impact on the mental health and psychosocial wellbeing of Syrian refugee OBJECTIVE This study aimed to identify the perceived symptoms of severe distress and impaired functioning, identify coping mechanisms and identify the barriers to access mental health services among Syrian refugees and Jordanian adults. METHODS This cross-sectional study study took place in 14 randomly selected sites in Jordan where Syrian refugees are concentered and from Za’tari refugee camp. A toolkit for humanitarian settings was used for data collection. RESULTS Of the 1424 participants, 43.4% had distress; 38.9% among host population, 57.0% among refugees in urban communities, and 23.0% among refugees in camp (p <0.005). Overall, finding comfort in faith and spiritual beliefs was the most common coping mechanism reported by those who perceived to be experiencing distress. CONCLUSIONS A significant proportion of Syrian refugees had distress symptoms. It is recommended to incorporate mental health services into broad-based community settings, such as schools, primary prevention or case management programs.


2007 ◽  
Vol 1 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Pradeep. S. Tangade

ABSTRACT The objectives of this study were to know the prevalence of anterior teeth fracture and malocclusion and their correlation among the school going children aged 12 and 15 years, as well as to analyze the general relative risk factors like age, sex, malocclusion, nature and place of trauma. Method An epidemiological cross sectional study was carried out among 3621 school going children (2418 boys and 1203 girls) in Belgaum city aged 12 and 15 years. Interview was conducted fro other variables and clinical examination using modified WHO performa was done. Results The prevalence of anterior teeth fracture was 4.41%. The prevalence rate for males was 4.96% and females 3.33%. The maxillary left central incisor had more risk for fracture (42.7%). Enamel fractures compromised of 59.54%. The prevalence rate of malocclusion was 27.3%. Conclusions The study concludes that there is a strong relationship between malocclusion and fractured anterior teeth (P<0.001). Key words: Malocclusion, Trauma, Prevalence, Tooth Fracture


Author(s):  
Anupama Pulla ◽  
Asma . ◽  
Nanduri Samyuktha ◽  
Soumya Kasubagula ◽  
Aishwarya Kataih ◽  
...  

Background: Computer vision syndrome is a complex of eye and vision problems related to near work which are experienced due to prolonged computer use. Computers demand near work, for longer duration which increases discomfort of eye and prolonged exposure to the discomfort leads to a cascade of symptoms that can be referred as computer vision syndrome. The aims and objectives of the study were to determine the prevalence of computer vision syndrome among engineering students of Hyderabad, Telangana and to determine the factors related to computer vision syndrome among study population.Methods: A cross sectional study was carried out from March to June 2017 among students of an engineering college in Hyderabad, Telangana. A convenient sample of 300 students was taken and a predesigned, pre tested questionnaire was used to obtain information.Results: Majority of study population were males (56.3%). Around 75.1% of study population were using all the electronic gadgets like computers, laptops and smartphones. The prevalence of computer vision syndrome was found to be 60.3%. Around 46.7% of study population viewed the screen from a distance of 22-40 centimeters.Conclusions: As students pursuing engineering stream are the future IT and Computer software engineers, preventive strategies adopted by them will significantly decrease the burden of computer vision syndrome and improve productivity. In this study a significant proportion of the engineering students were found to be having vision problems, which emphasizes the need to adopt preventive measures to avoid computer vision syndrome. 


Healthline ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 15-21
Author(s):  
Manish Jain ◽  
Mayank Jain ◽  
Vinod Kumar ◽  
Kapil Garg ◽  
Asif A Qureshi ◽  
...  

Introduction: The school going age is a formative period, both physically as well as mentally. Poor health status in school aged children is among the causes of poor class performance and high absenteeism. Objectives: to assess the health and nutritional status of the school going children in urban area and to determine the association of health problems with age and gender. Method: A cross sectional study was carried out in government schools of urban field practice area of tertiary care institute, Jhalawar, Rajasthan. Study was carried out among 2193 students in four government schools. A pretested, semi structured questionnaire was used for collection of data on socio-demographic characters and their health profile. A detailed clinical examination was done from head to toe for every child. Weight and height were measured. Data was entered into the Microsoft Excel 10. Chi square test of significance was used for statistical analysis. Results: Most common health problem was dental caries (15.0%) followed by refractive errors (13.1%) and pallor (12.6%). Proportions of pallor and refractive error were significantly increased with increase in age of study participants. 16.8% of the students were found to be having thinness. Moderate stunting was present in 7.3% students. Conclusion: Dental caries, refractive errors and pallor were the common morbidities. A significant proportion of school children were undernourished.


2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Muhammed Kutty Simin ◽  
Sarita Sasidharanpillai ◽  
Uma Rajan ◽  
Najeeba Riyaz

Objectives: With the rise in life expectancy at birth, geriatric population contributes to a significant proportion of those seeking medical aid. Skin problems in the elderly are very common and vary according to region and ethnicity. It is essential for dermatologists to have a better understanding of the pathophysiology of geriatric skin disorders to formulate quality management guidelines. This study was undertaken to document the frequency and the clinical pattern of various physiological and pathological changes in the elderly skin. Materials and Methods: A cross-sectional study was carried out in 200 consecutive patients aged 60 years and above and who attended the Dermatology outpatient clinic of a tertiary referral center in North Kerala. A pre-set pro forma was used to document the patient characteristics, the comorbidities, the medications used, and the clinical findings. Results: All the study participants (100%) had one or more dermatoses. The age of the study population ranged from 60 to 89 years (mean 67.7 ± 6.2 years). This was a female preponderant study with a female to male ratio of 1.4:1. Hypertension (36%), hyperlipidemia (27%) and diabetes mellitus (26%) were the common comorbidities observed. Graying of hair was the most common physiological change, followed by wrinkling. Pruritus was the most common presenting complaint (136, 68%). Statistically significant association was noted between xerosis and generalized pruritus. Fungal infections (30.5%) outnumbered other infections and infestations. Changes of severe photoaging were less frequent. One patient had skin malignancy (basal cell carcinoma). Significant association was noted between photoaging and male sex, smoking, and sun exposure. Limitations: Study conducted in a tertiary referral center not reflecting the status in the community was the major limitation. Conclusion: Photoaging and skin cancers are less frequent in darker skin type. Healthy lifestyle, nutritious diet, frequent application of emollient, better skin care, and judicious use of sunscreen can delay the process of cutaneous aging. More prospective studies in different population groups may go a long way in improving the current knowledge about the less known aspects of geriatric dermatoses.


2019 ◽  
Vol 20 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Abdur Rahim ◽  
Md. Moniruzzaman ◽  
Mostofa Kamal ◽  
Shah Golam Nabi ◽  
Supriya Sarkar ◽  
...  

Background: A large number of kala-azar cases from a particular village in Debigonj upazila of Panchaghar, a remote district of Bangladesh, led us to carry out the study of the situation. Materials & methods: This cross-sectional study was done among clinically screened people at the health camp in two days in Dararhat in Debigonj upazila of Panchaghar. Results: Around 700 people were screened at the health camp and 51 (7.2%) were suspected to have either Kala-azar or related disorders where 42 (82%) were rk-39 test positive. The disease was more prevalent among adult (59.6%) and children (23.8%) under the age of 10 years. However, there was no clear linear relationship between the prevalence of the disease and age group. Kala-azar occurred in both male and female, and its prevalence did not correlate significantly with income. A history of fever (73.8%) and splenomegaly (45.2%) was noted in most of the kala-azar cases. A significant number of PKDL (26.2%) cases were also found in that area. Conclusions: Since there are a significant proportion of PKDL cases, eradication will be very tough unless the health authority take adequate measure to identify and treat them properly. J MEDICINE JUL 2019; 20 (1) : 25-28


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
H. M. M. T. B. Herath ◽  
K. W. S. M. Wijayawardhana ◽  
U. I. Wickramarachchi ◽  
Chaturaka Rodrigo

Abstract Background Euthanasia is a topic of intense ethical debate and it is illegal in most countries at present, including Sri Lanka. The aim of this descriptive cross-sectional study of medical students and practicing doctors was to explore the acceptance of euthanasia and physician assisted suicide (PAS), and factors influencing this opinion. Methods A customised online questionnaire which explored opinions on euthanasia was administered to first and final year medical undergraduates in University of Colombo and practicing doctors with more than 5 years of work experience at The National Hospital of Sri Lanka. Attitudes on euthanasia and PAS were also assessed with the attitudes towards euthanasia (ATE) Scale, which is a 10-item questionnaire. Results A total of 425 individuals responded (males: 178, 42%, age: median – 27 years), which included 143 (33.6%) first-year medical undergraduates, 141 (33.2%) final-year medical undergraduates and 141 (33.2%) practicing doctors. More participants (200, 47.1%) favoured legalizing euthanasia than those directly opposing it (110, 25.9%), but a significant proportion (27%) remained undecided. The mean scores of ATE questionnaire from the whole sample were generally unfavourable towards euthanasia/PAS. Accepting euthanasia as an option for oneself (p =  < 0.001) was the strongest predictor of favouring euthanasia/PAS or supporting its legalization. Conclusion In this cross-sectional survey, more respondents supported legalisation of euthanasia in Sri Lanka than those openly opposing it. Yet, a significant minority that responded as “undecided” for legalisation, were more likely to have unfavourable ATE.


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