Evidence-based guidelines for interpreting change scores for the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30

2012 ◽  
Vol 48 (11) ◽  
pp. 1713-1721 ◽  
Author(s):  
K. Cocks ◽  
M.T. King ◽  
G. Velikova ◽  
G. de Castro ◽  
M. Martyn St-James ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Evidence Based ◽  
Life Questionnaire ◽  
Change Scores ◽  
Quality Of Life Questionnaire ◽  
European Organisation ◽  
Evidence Based Guidelines

The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with Bone Metastases: The EORTC QLQ-BM22

2009 ◽  
Vol 45 (7) ◽  
pp. 1146-1152 ◽  
Author(s):  
Edward Chow ◽  
Amanda Hird ◽  
Galina Velikova ◽  
Colin Johnson ◽  
Linda Dewolf ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Metastases ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
European Organisation ◽  
Eortc Qlq

scholarly journals The Square Curve Paradigm for Research in Alternative, Complementary, and Holistic Medicine: A Cost-Effective, Easy, and Scientifically Valid Design for Evidence-Based Medicine and Quality Improvement

2003 ◽  
Vol 3 ◽  
pp. 1117-1127 ◽  
Author(s):  
Soren Ventegodt ◽  
Niels JØrgen Andersen ◽  
Joav Merrick
Keyword(s):  
Quality Of Life ◽  
Evidence Based Medicine ◽  
Cost Effective ◽  
Holistic Medicine ◽  
Evidence Based ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
New Research ◽  
Based Medicine

In this paper we present a new research paradigm for alternative, complementary, and holistic medicine — a low-cost, effective, and scientifically valid design for evidence-based medicine. Our aim is to find the simplest, cheapest, and most practical way to collect data of sufficient quality and validity to determine: (1) which kinds of treatment give a clinically relevant improvement to quality of life, health, and/or functionality; (2) which groups of patients can be aided by alternative, complementary, or holistic medicine; and (3) which therapists have the competence to achieve the clinically relevant improvements. Our solution to the problem is that a positive change in quality of life must be immediate to be taken as caused by an intervention. We define “immediate” as within 1 month of the intervention. If we can demonstrate a positive result with a group of chronic patients (20 or more patients who have had their disease or state of suffering for 1 year or more), who can be significantly helped within 1 month, and the situation is still improved 1 year after, we find it scientifically evidenced that this cure or intervention has helped the patients. We call this characteristic curve a “square curve”. If a global, generic, quality-of-life questionnaire like QOL5 or, even better, a QOL-Health-Ability questionnaire (a quality-of-life questionnaire combined with a self-evaluated health and ability to function questionnaire) is administered to the patients before and after the intervention, it is possible to document the effect of an intervention to a cost of only a few thousand Euros/USD. A general acceptance of this new research design will solve the problem that there is not enough money in alternative, complementary, and holistic medicine to pay the normal cost of a biomedical Cochrane study. As financial problems must not hinder the vital research in nonbiomedical medicine, we ask the scientific community to accept this new research standard.

scholarly journals Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer

Head & Neck ◽  
2020 ◽  
Vol 42 (11) ◽  
pp. 3141-3152 ◽  
Author(s):  
Jammbe Z. Musoro ◽  
Corneel Coens ◽  
Susanne Singer ◽  
Silke Tribius ◽  
Sjoukje F. Oosting ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
European Organisation

European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal Cancer--Dutch Version

2016 ◽  
Author(s):  
A. M. Stiggelbout ◽  
M. Kunneman ◽  
M. C. M. Baas-Thijssen ◽  
P. A. Neijenhuis ◽  
A. K. Loor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Life Questionnaire ◽  
Dutch Version ◽  
Quality Of Life Questionnaire ◽  
European Organisation

Development of the European Organisation for Research and Treatment of Cancer quality of life questionnaire module for older people with cancer: The EORTC QLQ-ELD15

2010 ◽  
Vol 46 (12) ◽  
pp. 2242-2252 ◽  
Author(s):  
Colin Johnson ◽  
Deborah Fitzsimmons ◽  
Jacqueline Gilbert ◽  
Juan-Ignacio Arrarras ◽  
Eva Hammerlid ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older People ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
European Organisation ◽  
Eortc Qlq

scholarly journals Translation and cultural adaptation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Lung Cancer Module for quality of life assessment in patients with lung cancer in Brazil

2019 ◽  
Vol 45 (4) ◽  
Author(s):  
Ana Paula Ramos Marinho ◽  
Gracielle Fin ◽  
Antuani Rafael Baptistella ◽  
Rudy José Nodari Júnior ◽  
Magnus Benetti
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cultural Adaptation ◽  
Life Questionnaire ◽  
Pilot Testing ◽  
Language Version ◽  
Quality Of Life Questionnaire ◽  
European Organisation ◽  
Cancer Module

ABSTRACT Objective: To translate the European Organisation for Research and Treatment of Cancer (EORTC) 29-item Quality of Life Questionnaire-Lung Cancer Module (QLQ-LC29, developed for the assessment of quality of life in patients with lung cancer) to Portuguese, conducting a pilot study of the Portuguese-language version and adapting it for use in Brazil. Methods: For the translation, cultural adaptation, and pilot testing of the QLQ-LC29, we followed the guidelines established by the EORTC. The translation (English → Portuguese) and back-translation (Portuguese → English) were both carried out by translators, working independently, who were native speakers of one language and fluent in the other. After review, a draft version was created for pilot testing in lung cancer patients in Brazil. Results: A total of 15 patients diagnosed with lung cancer completed the Portuguese-language version of the questionnaire. At the end of the process, we conducted a structured interview to identify any patient difficulty in understanding any of the questions. The final versions were sent to the EORTC and were approved. Conclusions: The Portuguese-language version of the EORTC QLQ-LC29 appears to be a useful, important, reliable questionnaire that is a valid tool for assessing quality of life in patients with lung cancer in Brazil.

scholarly journals Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer (EORTC) Quality of life Questionnaire core 30 scores in patients with ovarian cancer

2020 ◽  
Vol 159 (2) ◽  
pp. 515-521
Author(s):  
Jammbe Z. Musoro ◽  
Corneel Coens ◽  
Elfriede Greimel ◽  
Madeleine T. King ◽  
Mirjam A.G. Sprangers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ovarian Cancer ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
European Organisation ◽  
Eortc Quality

Evidence-Based Guidelines for Determination of Sample Size and Interpretation of the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30

2011 ◽  
Vol 29 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Kim Cocks ◽  
Madeleine T. King ◽  
Galina Velikova ◽  
Marrissa Martyn St-James ◽  
Peter M. Fayers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sample Size ◽  
Clinical Relevance ◽  
Meta Analysis ◽  
Performance Status ◽  
Age Groups ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
European Organisation

Purpose To use published literature to estimate large, medium, and small differences in quality of life (QOL) data from the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Methods An innovative method combining systematic review of published studies, expert opinions, and meta-analysis was used to estimate large, medium, and small differences for QLQ-C30 scores. Published mean data were identified from the literature. Differences (contrasts) between groups (eg, between treatment groups, age groups, and performance status groups) were reviewed by 34 experts in QOL measurement and cancer treatment. The experts, blinded to actual QOL results, were asked to predict these differences. A large difference was defined as one representing unequivocal clinical relevance. A medium difference was defined as likely to be clinically relevant but to a lesser extent. A small difference was one believed to be subtle but nevertheless clinically relevant. A trivial difference was used to describe circumstances unlikely to have any clinical relevance. Actual QOL results were combined using meta-analytic techniques to estimate differences corresponding to small, medium, or large effects. Results Nine hundred eleven articles were identified, leading to 152 relevant articles (2,217 contrasts) being reviewed by at least two experts. Resulting estimates from the meta-analysis varied depending on the subscale. Thus, the recommended minimum to detect medium differences ranges from 9 (cognitive functioning) to 19 points (role functioning). Conclusion Guidelines for the size of effects are provided for the QLQ-C30 subscales. These guidelines can be used for sample size calculations for clinical trials and can also be used to aid interpretation of differences in QLQ-C30 scores.

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