Meconium-stained amniotic fluid and histologic signs of fetal distress in stillbirths

2021 ◽  
Author(s):  
Avagliano Laura ◽  
Massa Valentina ◽  
Bulfamante Gaetano
Keyword(s):  
Amniotic Fluid ◽  
Fetal Distress ◽  
Meconium Stained Amniotic Fluid

scholarly journals Maternal and fetal outcome in term labour with meconium stained amniotic fluid

2012 ◽  
Vol 10 (3) ◽  
pp. 198-202
Author(s):  
S Kumar ◽  
SN Gupta ◽  
IP Mahato ◽  
R Giri ◽  
A Yadav ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Mode Of Delivery ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Delivery Methods ◽  
Normal Delivery ◽  
Term Labour ◽  
Meconium Stained Amniotic Fluid ◽  
Control Study ◽  
Additional Monitoring

Introduction: Passage of meconium in utero is a dangerous sign for fetal outcome which influence the decision to deliver as well as the mode of delivery. Methods: This descriptive case control study was carried out in the department of Obstetrics and Gynaecology, Koshi Zonal Hospital from March 2006 to July 2006. A total of 50 women with meconium stained amniotic fluid( MSAF) were studied to identify maternal and fetal outcome and was compared with women with clear amniotic fluid. Results: Normal delivery was significantly higher (58%) in clear liquor group as compared to MSAF group (22%). Cesarean section was more common in MSAF group (66%) where as it was (38%) in the clear liquor group (p=0.005). Low Apgar scores of < 5 at one minute was seen in 48% of MSAF and 6% of clear liquor born babies (p<0.2). But at 5 minutes low Apgar score persisted in same 48% of MSAF babies whereas it was seen in 12% of clear liquor group (p<0.000). Among the babies born with MSAF 34% were referred to higher center compared to 6% in clear liquor babies (p=0.000). Four babies with thick MSAF and one baby with clear liquor had neonatal death (p=0.005). Conclusion: Mode of delivery and fetal outcome were adversely affected by the presence of thick meconium stained liquor as compared to clear liquor. Additional monitoring facilities e.g. cardiotocography (CTG) if available would reduce fetal distress and allow timely intervention in such cases. DOI: http://dx.doi.org/10.3126/hren.v10i3.7135 Health Renaissance; September-December 2012; Vol 10 (No.3);198-202

scholarly journals Comparison of Perinatal Outcomes between Borderline and Normal Amniotic Fluid Index in Term Singleton Pregnancies

2021 ◽  
Vol 18 (4) ◽  
pp. 709-713
Author(s):  
Nishma Bajracharya ◽  
Ganesh Dangal ◽  
Rekha Poudel ◽  
Kenusha Devi Tiwari ◽  
Sonu Bharati ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Perinatal Outcome ◽  
Neonatal Intensive Care ◽  
Perinatal Outcomes ◽  
Fetal Distress ◽  
Normal Group ◽  
Amniotic Fluid Index ◽  
Safe Delivery ◽  
Meconium Stained Amniotic Fluid ◽  
Singleton Pregnancies

Background: Amniotic fluid provides necessary fluid and growth factors for normal development of fetal lungs, cushions the umbilical cord from compression and protects the fetus. This study aims to compare the perinatal outcome between pregnancy with borderline and normal Amniotic Fluid Index that provide greatest chance for appropriate safe delivery with least maternal fetal and neonatal risk.Methods: A total of 94 singleton full term pregnant women were included in the study-at Kathmandu Model Hospital from February to August 2020. Forty Seven women each with Amniotic Fluid Index 5-8 cm was taken as borderline oligohydramnios group and Amniotic Fluid Index 8.1-24 cm was taken as normal group. Ultrasonography was taken as the medium for measuring Amniotic Fluid Index.Results: The rate of intra-partum fetal distress, meconium-stained amniotic fluid, low birth weight and neonatal intensive care unit admission were not statistically significant between the two groups while rate of cesarean section was noted to be 76.6% in exposed groups as compared to 44.7% among women with non-exposed normal group [RR=1.71; 95%CI: 1.2-2.44 p=0.006]. Conclusions: We concluded that in cases of borderline oligohydramnios there was higher risk of operative delivery.Keywords: Adverse perinatal outcome; amniotic fluid; borderline oligohydramnios; meconium-stained amniotic fluid

scholarly journals Clinical profile of babies with meconium stained amniotic fluid

2017 ◽  
Vol 5 (10) ◽  
pp. 4319
Author(s):  
Defairlin Ranee ◽  
Deepa S. Phirke
Keyword(s):  
Amniotic Fluid ◽  
Strong Association ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Fetal Distress ◽  
Meconium Aspiration Syndrome ◽  
Clinical Profile ◽  
Meconium Aspiration ◽  
Increased Risk ◽  
Meconium Stained Amniotic Fluid

Background: Meconium staining of amniotic fluid (MSAF) is a relatively common problem occuring in 10-25% of all deliveries. Meconium aspiration syndrome is more common in term babies than in preterm babies with rising frequency along with increase in gestational age of the fetus. Meconium stained amniotic fluid generally indicates sign of fetal distress. The objective of this study was to study clinical profile of meconium aspiration syndrome and the probable risk factors for meconium aspiration syndrome.Methods: It is a prospective observational sectional study conducted in NICU of department of paediatrics of tertiary care centre from 1st January 2015 to 30th June 2016.Results: In this study both sexes were equally affected, majority of the neonates were above 2.5kg and only very few (2 neonates) were less than 1.5kg. majority of the neonates were full term, it was found that there is a significant association between thick MSAF and the development of MAS, it was found that there is a significant association between low APGAR score at 1 minutes and the development of MAS, there is a strong association between thick MSAF and mortality in MSAF babies. Anemia 38 (25%) was the most frequent perinatal risk factor followed by fetal distress 27 (18) and PIH 21 (14%).Conclusions: Newborns with thick MSAF were more likely to develop MAS and thick MSAF and low APGAR at 1 min were associated with high risk of development of MAS. Passage of thick meconium was significantly associated with severe birth asphyxia and carried a bad prognosis with increased risk of development of meconium aspiration syndrome and hypoxic ischaemic encephalopathy.

scholarly journals Meconium stained liquor and fetal outcome: a hospital based follow up study

2019 ◽  
Vol 8 (6) ◽  
pp. 2434
Author(s):  
P. Kalpana ◽  
A. Kavitha
Keyword(s):  
Amniotic Fluid ◽  
Apgar Score ◽  
Neonatal Morbidity ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Meconium Aspiration Syndrome ◽  
Chi Square ◽  
Mortality And Morbidity ◽  
Meconium Staining ◽  
Meconium Stained Amniotic Fluid

Background: Meconium staining of the amniotic fluid is a common problem occurring in 10-22% of all deliveries. Meconium aspiration syndrome complicates approximately 1.5% of these deliveries with a reported mortality rate as high as 40%. Objectives of the study were to determine whether meconium stained liquor during labour is associated with fetal distress and to check if there is any correlation in between the degree of meconium staining liquor and fetal outcome.Methods: A clinical study of 200 cases of meconium stained amniotic fluid in cephalic presentation was undertaken among patients who were admitted in labour room were examined in detail and investigations were done. Fetal heart rate and its pattern were noted every fifteen min. Total APGAR score at one minute and five minute was noted down. Odds ratio with 95% confidence interval was calculated. Proportions were analyzed using chi square value.Results: Majority of the study subjects belonged to the age group of 21-30 years. Majority i.e. 54.5% were multigravida. Majority had toxemia in 24% of the cases. Fetal distress and the incidence of forceps delivery or LSCS was significantly more in those with thick meconium compared to those with thin meconium (p<0.05). But fetal asphyxia was not associated with type of stained meconium. It is seen that as the duration of the meconium staining increased, the proportion of babies with low APGAR score, perinatal mortality and morbidity increased.Conclusions: Thick meconium stained amniotic fluid was associated with increased rate of interventions, neonatal morbidity and mortality compared to thin meconium stained meconium fluid.

scholarly journals Clinical study of babies born through meconium stained amniotic fluid

2019 ◽  
Vol 6 (2) ◽  
pp. 491 ◽  
Author(s):  
Shilpasri Y. M. ◽  
Madhurya B.
Keyword(s):  
Amniotic Fluid ◽  
Mode Of Delivery ◽  
Birth Asphyxia ◽  
Fetal Monitoring ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
Medical College ◽  
Meconium Stained Amniotic Fluid

Background: Meconium stained amniotic fluid has been considered a sign of fetal distress and associated with poor fetal outcome, but others considered meconium passage by fetus is physiological phenomena and produce environmental hazards to fetus before birth. Such magnitude of different opinion was the object behind taking up of this study and aim was to find out incidence and effect of meconium in terms of morbidity and mortality.Methods: Two hundred babies born with meconium stained amniotic fluid considering the inclusion and exclusion criteria from December 2012 to June 2013 in the Department of Paediatrics, Cheluvamba hospital attached to Mysore Medical College and Research Institute, Mysore. Fetal monitoring, mode of delivery, Apgar score, birth weight, resuscitation of baby are noted. All babies followed-up up to 1st week of neonatal life.Results: In present study 200 babies born through meconium stained amniotic fluid was randomly selected-thin 37% and thick 63%. Major complications like birth asphyxia, meconium aspiration syndrome, early neonatal death seen in 5.5% (11 cases), morbidity in 37%, 12.5% in thin and 24.5% in thick MSAF. Causes of death were meconium aspiration syndrome in 3 cases, sepsis in 1 case, pneumonia in 1 case and birth asphyxia in 6 cases.Conclusions: Immediate airway management, need for suction and intubation should be guided by state of newborn rather than presence of meconium. Timely diagnosis and management of meconium stained amniotic fluid may improve fetal outcome. From present study authors conclude that MSAF adversely affect fetal outcome mostly by thick meconium.

scholarly journals Utility of amnioinfusion in deliveries complicated by meconium stained liquor: a randomized controlled trial

2016 ◽  
Vol 6 (1) ◽  
pp. 65
Author(s):  
Mervat A. Elsersy
Keyword(s):  
Amniotic Fluid ◽  
Controlled Trial ◽  
Randomized Study ◽  
Fetal Distress ◽  
Meconium Aspiration Syndrome ◽  
Controlled Clinical Trial ◽  
Randomized Controlled ◽  
Group 2 ◽  
Meconium Stained Amniotic Fluid ◽  
Inexpensive Procedure

Background: Meconium stained amniotic fluid could be seen in 12-16 % of deliveries. Meconium is toxic to the newborn lung. Its presence during labour increases the risk to develop neonatal respiratory distress by about 100 times more. Meconium aspiration syndrome (MAS) occurs in about 5% of deliveries with meconium-stained amniotic fluid and death occurs in about 12% of infants with MAS. Intrapartum amnioinfusion was described as a way to dilute meconium or act as a mechanical cushioning of the umbilical cord to prevent its compression .The aim of this study is to perform a randomized controlled clinical trial to test the hypothesis that amnioinfusion can reduce the incidence of caesarean deliveries and perinatal morbidity associated with meconium stained amniotic fluid.Methods: An interventional randomized study was conducted in Hai Jamaa hospital. 360 patients were enrolled in the study. The patients were in labour with meconium stained liquor above 37 weeks. They were randomly allocated in two groups. Group 1: amnioinfusion group and Group 2: non amnioinfusion group.Results: Significant reduction of cesarean section rate due to fetal distress. Also significant reduction of prevalence of variable fetal heart rate decelerations, and significant reduction of incidence of MAS in patients received amnioinfusion.Conclusions: Amnioinfusion is an easy, safe and inexpensive procedure useful in patients with meconium stained liquor.

scholarly journals Outcome of neonates born through Meconium stained amniotic fluid in tertiary health care centre

2018 ◽  
Vol 5 (2) ◽  
pp. 569
Author(s):  
Girish N. ◽  
Shravani M. R. ◽  
Thrashree C. D. ◽  
Sunil B.
Keyword(s):  
Respiratory Distress ◽  
Amniotic Fluid ◽  
Prospective Observational Study ◽  
Clinical Course ◽  
Mode Of Delivery ◽  
Fetal Distress ◽  
Morbidity And Mortality ◽  
Health Care Centre ◽  
Maternal Illness ◽  
Meconium Stained Amniotic Fluid

Background: Meconium Aspiraion Syndrome (MAS) is an important cause of morbidity and mortality among newborns in the developing world. Meconium stained amniotic fluid (MSAF) occurs in approximately 13% of all live births.Methods: This was a prospective observational study to assess the risk factors related with MSAF deliveries and MAS. All the details regarding mode of delivery, APGAR score (AS), birth weight, fetal distress, maternal age, any maternal illness, gestational age, clinical course, outcome was recorded and evaluated.Results: In the present study total of 100 babies born through MSAF were included of which the incidence of respiratory distress was noted in 62% (62 babies).Conclusions: Appropriate monitoring of respiratory distress at birth and assessing the high-risk cases will surely help in reducing the morbidity and mortality in vigorous babies born through MSAF.

scholarly journals STUDY OF VARIOUS FACTORS FOR MECONIUM STAINED AMNIOTIC FLUID (MSAF) AND COMPARISON OF FETAL OUTCOMES IN MECONIUM STAINED AMNIOTIC FLUID AND CLEAR AMNIOTIC FLUID CONTRIBUTORS

2020 ◽  
pp. 71-73
Author(s):  
Kajal Kunwar ◽  
Shanti HK Singh
Keyword(s):  
Amniotic Fluid ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Fetal Distress ◽  
Fetal Outcome ◽  
Clinical Impression ◽  
Care Hospital ◽  
Maternal Hypertension ◽  
Meconium Staining ◽  
Meconium Stained Amniotic Fluid

Aims and objectives: To identify various factors for meconium stained amniotic fluid (MSAF) and comparison of pregnancy outcome in meconium stained vs. clear amniotic fluid. Material and Methods: The study was conducted at the Department of Obstetrics and Gynaecology of a teaching tertiary care hospital. Out of 850 deliveries, 100 cases of MSAF were studied for 17 months. Detection of MSAF during delivery and follow-up of mother and baby during hospital stay was done. Results: Overall incidence of meconium staining of AF during labor was in the present study 11.6%. The incidence of meconium staining was much greater in postdated pregnancy and oxytocin-induced labor. Birth asphyxia was more common when the AF was meconium stained and severity was directly proportional to the degree of thickness of MSAF. Abnormal heart rate was much more frequent in the study group and when thick meconium was associated with bradycardia fetal outcome was worst. Conclusion: Prevention of fetal distress and maternal hypertension can reduce MSAF to ultimately minimize cesarean /instrumental delivery and adverse fetal outcome. This study confirmed that our clinical impression– “meconium staining of amniotic fluid adversely influence the fetal outcome”

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