Utility of preoperative computed tomography features in predicting the Ki-67 labeling index of gastric gastrointestinal stromal tumors

2021 ◽  
pp. 109840
Author(s):  
Xiao-Shan Chen ◽  
Ying-Chan Shan ◽  
San-Yuan Dong ◽  
Wen-Tao Wang ◽  
Yu-Tao Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Gastrointestinal Stromal Tumors ◽  
Labeling Index ◽  
Ki 67 ◽  
Stromal Tumors

Multislice imaging of gastrointestinal stromal tumors

2018 ◽  
pp. 3-14
Keyword(s):  
Computed Tomography ◽  
Key Words ◽  
Gold Standard ◽  
Gastrointestinal Stromal Tumors ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Preferential Localization ◽  
Multislice Imaging ◽  
Computed Tomography Diagnosis

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract (1%). These tumors express the CD 117 in 95% of cases. The stomach is the preferential localization (70%). Diagnosis is difficult and sometimes late. Progress of imaging has greatly improved the management and the prognosis. Computed tomography (CT) is the gold standard for diagnosis, staging, and treatment follow-up. The increasing recognition of GIST’s histopathology and the prolonged survival revealed some suggestive imaging aspects. Key words: gastro-intestinal stromal tumors; computed tomography; diagnosis

scholarly journals Surgical Management of Benign Gastric Tumors: A Review

2021 ◽  
pp. 420-426
Author(s):  
Hashem Bark Awadh Abood ◽  
Amani Nasser D. Albalawi ◽  
Haifa Obedullah AlEnazi ◽  
Mousa Mutlaq Almuhanna ◽  
Norah Othman Busaad ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Gastrointestinal Stromal Tumors ◽  
Laparoscopic Resection ◽  
Benign Tumors ◽  
Stromal Tumors ◽  
Gastric Tumors ◽  
Laparoscopic Excision ◽  
Long Time ◽  
The Difference ◽  
Stomach Epithelium

Benign stomach and duodenal tumors are uncommon. Any component of the stomach epithelium, whether glandular, endocrine, or mesenchymal, can develop benign neoplastic tumors. The majority of people with benign stomach and duodenal tumors are asymptomatic for a long time. When symptoms do appear, they are determined by the tumor's size, location, and comorbidities. Endoscopy, computed tomography, and especially endoscopic ultrasonography results are used diagnose. Clinically, it's difficult to tell the difference between benign and malignant stomach tumors. Even benign tumors can undergo malignant transformation, severe obstructive problems, and bleeding. As a result, aggressive surgical resection of the tumors should be undertaken. Laparoscopic resection has become the first option of many surgeons since the development of minimally invasive surgery. According to previous literature, laparoscopic excision of GIST is safe and effective. In this review we’ll be looking at benign gastric tumors, gastrointestinal stromal tumors (GISTs) and their diagnosis.

Gastrointestinal Stromal Tumors: A “Benign” Tumor with Hepatic Metastasis after 11 Years

1998 ◽  
Vol 84 (1) ◽  
pp. 78-81 ◽  
Author(s):  
Carlo Ballarini ◽  
Mattia Intra ◽  
Andrea Pisani Ceretti ◽  
Francesco Prestipino ◽  
Filippo Maria Bianchi ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Hepatic Metastasis ◽  
Tumor Size ◽  
Gastrointestinal Stromal Tumors ◽  
Cellular Proliferation ◽  
Malignant Potential ◽  
Mitotic Count ◽  
Proliferation Index ◽  
Ki 67 ◽  
Stromal Tumors

Gastrointestinal stromal tumors (GIST) constitue the largest category of primary non-epithelial neoplasms of the stomach and small bowel. They are characterized by a remarkable cellular variability and their malignant potential is sometimes difficult to predict. Very recent studies, using mitotic count and tumor size as the best determinants of biological behavior, divide GISTs into three groups: benign, borderline and malignant tumors. We report on a male patient who underwent a right hepatectomy for a large metastasis 11 years after the surgical treatment of an antral-pyloric gastric neoplasm, histologically defined as leiomyoblastoma and with clinical, morphological and immunohistochemical features of benignity (low mitotic count, tumor size < 5 cm, low cellular proliferation index). Histological and immunohistochemical analysis of the hepatic metastasis showed the cellular proliferation index (Ki-67) to be positive in 25% of neoplastic cells, as opposed to the primary gastric tumor in which Ki-67 was positive in only 5% of neoplastic cells. In conclusion, although modern immunohistochemical techniques are now available to obtain useful prognostic information, the malignant potential of GISTs is sometimes difficult to predict: neoplasms clinically and histologically defined as benign could metastasize a long time after oncologically correct surgical treatment. Therefore, benign GISTs also require consistent, long-term follow-up.

Radiomics of Gastrointestinal Stromal Tumors; Risk Classification Based on Computed Tomography Images – A Pilot Study

2020 ◽  
Vol 46 (2) ◽  
pp. e6
Author(s):  
Milea Timbergen ◽  
Martijn P.A. Starmans ◽  
Melissa Vos ◽  
Michel Renckens ◽  
Dirk J. Grünhagen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pilot Study ◽  
Gastrointestinal Stromal Tumors ◽  
Risk Classification ◽  
Stromal Tumors ◽  
Computed Tomography Images
Sign in / Sign up

Export Citation Format

Share Document