Long-term outcome and prognostic factors of intrahepatic cholangiocarcinoma involving the hepatic hilus versus hilar cholangiocarcinoma after curative-intent resection: Should they be recognized as perihilar cholangiocarcinoma or differentiated?

2019 ◽  
Vol 45 (11) ◽  
pp. 2173-2179 ◽  
Author(s):  
Jiong Lu ◽  
Bei Li ◽  
Fu-Yu Li ◽  
Hui Ye ◽  
Xian-Ze Xiong ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Intrahepatic Cholangiocarcinoma ◽  
Hilar Cholangiocarcinoma ◽  
Perihilar Cholangiocarcinoma ◽  
Curative Intent ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Hepatic Hilus

Long-Term Outcome and Prognostic Factors in Non-Benign Meningiomas

2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Christian Schichor ◽  
Anna-Maria Biczok ◽  
Kraus Theo ◽  
Niklas Thon ◽  
Jörg-Christian Tonn
Keyword(s):  
Prognostic Factors ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3661
Author(s):  
Jan Bednarsch ◽  
Xiuxiang Tan ◽  
Zoltan Czigany ◽  
Dong Liu ◽  
Sven Arke Lang ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Intrahepatic Cholangiocarcinoma ◽  
Cox Regression ◽  
Oncological Outcome ◽  
Nerve Fibers ◽  
Nodal Metastases ◽  
Cancer Specific Survival ◽  
Curative Intent ◽  
Term Outcome ◽  
Long Term Outcome

The oncological role of the density of nerve fibers (NFs) in the tumor microenvironment (TME) in intrahepatic cholangiocarcinoma (iCCA) remains to be determined. Therefore, data of 95 iCCA patients who underwent hepatectomy between 2010 and 2019 was analyzed regarding NFs and long-term outcome. Extensive group comparisons were carried out and the association of cancer-specific survival (CSS) and recurrence-free survival (RFS) with NFs were assessed using Cox regression models. Patients with iCCA and NFs showed a median CSS of 51 months (5-year-CSS = 47%) compared to 27 months (5-year-CSS = 21%) in patients without NFs (p = 0.043 log rank). Further, NFs (hazard ratio (HR) = 0.39, p = 0.002) and N-category (HR = 2.36, p = 0.010) were identified as independent predictors of CSS. Patients with NFs and without nodal metastases displayed a mean CSS of 89 months (5-year-CSS = 62%), while patients without NFs or with nodal metastases but not both showed a median CCS of 27 months (5-year-CSS = 25%) and patients with both positive lymph nodes and without NFs showed a median CCS of 10 months (5-year-CSS = 0%, p = 0.001 log rank). NFs in the TME are, therefore, a novel and important prognostic biomarker in iCCA patients. NFs alone and in combination with nodal status is suitable to identify iCCA patients at risk of poor oncological outcomes following curative-intent surgery.

scholarly journals Long-Term Outcome and Prognostic Factors of Sporadic Colorectal Cancer in Young Patients

Medicine ◽  
2016 ◽  
Vol 95 (19) ◽  
pp. e3641 ◽  
Author(s):  
Tae Jun Kim ◽  
Eun Ran Kim ◽  
Sung Noh Hong ◽  
Dong Kyung Chang ◽  
Young-Ho Kim
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factors ◽  
Young Patients ◽  
Sporadic Colorectal Cancer ◽  
Term Outcome ◽  
Long Term Outcome

Prognostic Factors and Longitudinal Change in Long-Term Outcome of Frontal Lobe Epilepsy Surgery

2019 ◽  
Vol 121 ◽  
pp. e32-e38 ◽  
Author(s):  
Cuiping Xu ◽  
Tao Yu ◽  
Guojun Zhang ◽  
Yuping Wang ◽  
Yongjie Li
Keyword(s):  
Prognostic Factors ◽  
Frontal Lobe ◽  
Epilepsy Surgery ◽  
Longitudinal Change ◽  
Frontal Lobe Epilepsy ◽  
Term Outcome ◽  
Long Term Outcome
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