Background:
Peptic ulcer is a deep gastrointestinal erosion disorder that involves
the entire mucosal thickness and can even penetrate the muscular mucosa. Nowadays, several
plants and compounds derived from it have been screened for their antiulcer activity. In
the last few years, there has been an exponential growth in the field of herbal medicine. This
field has gained popularity in both developing and developed countries because of their natural
origin and less side effects.
Objective:
This review aims to provide a comprehensive summary of currently available
knowledge of medicinal plants and phytoconstituents reported for their anti-ulcer properties.
Methods:
The worldwide accepted database like SCOPUS, PUBMED, SCIELO, NISCAIR,
ScienceDirect, Springerlink, Web of Science, Wiley, SciFinder and Google Scholar were
used to retrieve available published literature.
Results:
A comprehensive review of the present paper is an attempt to list the plants with
antiulcer activity. The review narrates the dire need to explore potential chemical moieties
that exert an antiulcer effect, from unexploited traditional plants. Furthermore, the present
study reveals the intense requirement to exploit the exact mechanism through which either
the plant extracts or their active constituents exhibit their antiulcer properties.
Conclusion:
This article is the compilation of the plants and its constituents reported for the
treatment of peptic ulcers. The Comprehensive data will surely attract the number of investigators
to initiate further research that might lead to the drugs for the treatment of ulcers. As
sufficient scientific data is not available on plants, most of the herbals cannot be recommended
for the treatment of diseases. This can be achieved by research on pure chemical
structures derived from plants or to prepare new lead compounds with proven beneficial
preclinical in vitro and in vivo effects. However, a lot remains to be done in further investigations
for the better status of medicinal plants.
Design and in vitro/in vivo evaluations of a multiple-drug-containing gingiva disc for periodontotherapy
