Gardenia jasminoides Ellis ethanol extract and its constituents reduce the risks of gastritis and reverse gastric lesions in rats

2009 ◽  
Vol 47 (6) ◽  
pp. 1127-1131 ◽  
Author(s):  
Je-Hyuk Lee ◽  
Dong-Ung Lee ◽  
Choon-Sik Jeong
Keyword(s):  
Ethanol Extract ◽  
Gastric Lesions ◽  
Gardenia Jasminoides ◽  
Gardenia Jasminoides Ellis

scholarly journals Antibacterial Activities of Kacapiring Leaf Ethanol Extract (Gardenia jasminoides Ellis) on the Bacteria of Staphylococcus aureus and Propionibacterium acnes

MEDULA ◽  
2019 ◽  
Vol 6 (3) ◽  
Author(s):  
Nuralifah Nuralifah ◽  
Fery Indradewi Armadani ◽  
Ni Nyoman Fitri Astari
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Propionibacterium Acnes ◽  
Ethanol Extract ◽  
The Body ◽  
Plate Technique ◽  
Gardenia Jasminoides ◽  
Gardenia Jasminoides Ellis ◽  
Inhibitory Power

ABSTRACTBackground and Objective(s): Infection is the process of entering pathogenic bacteria or microorganisms into the body capable of causing disease. Bacterial infections can cause skin infections such as acne. Acne is inflammation that is accompanied by blockage of the oil glands of the skin and hair (pilosebasea duct). Gardenia jasminoides Ellis is a plant that empirically can be used to treat infectious diseases caused by bacteria. This study was conducted to determine the antibacterial activity of the extracts of kacapiring leaves (Gardenia jasminoides Ellis) against Staphylococcus aureus and Propionibacterium acnes bacteria. Methods: Making extracts was done by maceration method  using  96% ethanol. The concentrations of extracts  used  were 5%, 10% and  15%,  with chloramphenicol and clindamycin as positive controls and distilled water as negative controls. Antibacterial activity was tested by the Cup-plate technique. Results: The antibacterial activity of kacapiring leaves ethanol extract to S. aureus showed that at concentrations of 5%, 10% and 15% the inhibitory power diameters values were respectively 5.58 mm, 9.3 mm and 11.41 mm while the antibacterial activity of extracts kacapiring leaves ethanol to P. acnes bacteria at concentrations of 5%, 10% and 15% had inhibitory power diameters of 6.33 mm, 9.25 mm and 11 mm respectively. Conclusion: Ethanol extract of kacapiring leaves has antibacterial activity against Staphylococcus aureus and Propionibacterium acnes bacteria. At a concentration of 5% and 10%, it shows the moderate category and at a concentration of 15% shows a strong category.Keywords: antibacterial, cup-plate technique , gardenia jasminoides

TRANCRIPTOMIC STUDY OF FLOWER PETAL SENESCENCE IN GARDENIA JASMINOIDES ELLIS USING ILLUMINA HI-SEQ TECHNOLOGY

2015 ◽  
pp. 331-334 ◽  
Author(s):  
G.F. Tsanakas ◽  
M.E. Manioudaki ◽  
P. Kalaitzis ◽  
A.S. Economou ◽  
S. Kintzios
Keyword(s):  
Petal Senescence ◽  
Flower Petal ◽  
Gardenia Jasminoides ◽  
Gardenia Jasminoides Ellis

scholarly journals Chemical Composition of Essential Oil from Flower of ‘Shanzhizi’ (Gardenia jasminoides Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4702
Author(s):  
Nan Zhang ◽  
Mu Luo ◽  
Lei He ◽  
Lei Yao
Keyword(s):  
Essential Oil ◽  
Elevated Plus Maze ◽  
Anxiolytic Effect ◽  
Serotonergic System ◽  
Control Treatment ◽  
Monoamine Neurotransmitters ◽  
Neurotransmitter Receptor ◽  
Gardenia Jasminoides ◽  
Plus Maze ◽  
Gardenia Jasminoides Ellis

Gardenia jasminoides Ellis is a famous fragrant flower in China. Previous pharmacological research mainly focuses on its fruit. In this study, the essential oil of the flower of ‘Shanzhizi’, which was a major variety for traditional Chinese medicine use, was extracted by hydro distillation and analyzed by GC-MS. Mouse anxiety models included open field, elevated plus maze (EPM), and light and dark box (LDB), which were used to evaluate its anxiolytic effect via inhalation. The involvement of monoamine system was studied by pretreatment with neurotransmitter receptor antagonists WAY100635, flumazenil and sulpiride. The monoamine neurotransmitters contents in the prefrontal cortex (PFC) and hippocampus after aroma inhalation were also analyzed. The results showed that inhalation of G. jasminoides essential oil could significantly elevated the time and entries into open arms in EPM tests and the time explored in the light chamber in LDB tests with no sedative effect. WAY100635 and sulpiride, but not flumazenil, blocked its anxiolytic effect. Inhalation of G. jasminoides essential oil significantly down-regulated the 5-HIAA/5-HT in the PFC and reduced the 5-HIAA content in hippocampus compared to the control treatment. In conclusion, inhalation of gardenia essential oil showed an anxiolytic effect in mice. Monoamine, especially the serotonergic system, was involved in its anxiolytic effect.

scholarly journals Regulation of PI3k-WNK Pathway by Ethyl Acetate Partition Fraction of Gardenia jasminoides var. radicans Makino in SHR, NRK52e Cells, and IMCD3 Cells

2020 ◽  
Vol 15 (4) ◽  
pp. 1934578X2092098
Author(s):  
Yang Fu ◽  
Peipei Yuan ◽  
Yingying Ke ◽  
Yangang Cao ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ethyl Acetate ◽  
Ethanol Extract ◽  
Ethyl Acetate Fraction ◽  
Pi3k Pathway ◽  
Reduce Blood Pressure ◽  
Chemical Compositions ◽  
Spontaneously Hypertensive ◽  
Messenger Ribonucleic Acid ◽  
Gardenia Jasminoides

The antihypertensive mechanism was studied of the ethyl acetate fraction of the ethanol extract (EAPF) of Gardenia jasminoides var. radicans Makino (GJRM). GJRM is a fake product of Gardenia jasminoides Ellis ( G. jasminoides), but in China’s Henan province, the production of GJRM is much more than G. jasminoides’s, but its traditional usage is as a dye. Gardenia jasminoides can be used to reduce blood pressure and blood glucose levels. The chemical compositions of GJRM and G. jasminoides are similar, and we previously confirmed that GJRM can also reduce blood pressure. Here, we report that the EAPF of GJRM could activate the phosphoinositide 3-kinases (PI3K) pathway in the kidneys of spontaneously hypertensive rats, thus increasing the content of nitric oxide and bradykinin in sera and decreasing endothelin-1 content. EAPF can also decrease the levels of with-no-lysine kinase 1 (WNK1) expression, WNK4 and oxidative stress-responsive kinase 1 messenger ribonucleic acid (mRNA), and Na-K-2Cl cotransporter and sodium chloride cotransporters mRNA and phosphorylation. To investigate the antihypertensive effects of the EAPF of GJRM, 5 monoterpenoids isolated from EAPF were studied for their effects on NRK52e and IMCD3 cells. These compounds inhibited the PI3K-WNK signaling pathway to varying degrees under hypotonic conditions; 4-methoxyrehmapicrogenin had the best effect.

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