scholarly journals Adverse effects of prolonged use of pausinystalia yohimbe on sperm and reproductive organs in rats

2017 ◽  
Vol 108 (3) ◽  
pp. e314
Author(s):  
L.C. Ajonuma ◽  
S.A. Bamiro ◽  
S.L. Makanjuola
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs

scholarly journals Early indicators of delayed adverse effects in female reproductive organs in rats receiving neonatal exposure to 17alpha-ethynylestradiol

2014 ◽  
Vol 39 (5) ◽  
pp. 775-784 ◽  
Author(s):  
Miwa Takahashi ◽  
Kaoru Inoue ◽  
Tomomi Morikawa ◽  
Saori Matsuo ◽  
Seigo Hayashi ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs ◽  
Neonatal Exposure ◽  
Female Reproductive Organs ◽  
Early Indicators

scholarly journals Nandrolone Decanoate: Use, Abuse and Side Effects

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 606
Author(s):  
Federico Giuseppe Patanè ◽  
Aldo Liberto ◽  
Andreana Nicoletta Maria Maglitto ◽  
Pasquale Malandrino ◽  
Massimiliano Esposito ◽  
...  
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Adverse Effects ◽  
English Language ◽  
Scientific Literature ◽  
Reproductive Organs ◽  
Nandrolone Decanoate ◽  
Inclusion Criteria ◽  
Pubmed Database ◽  
Study Results

Background and Objectives: Androgens play a significant role in the development of male reproductive organs. The clinical use of synthetic testosterone derivatives, such as nandrolone, is focused on maximizing the anabolic effects and minimizing the androgenic ones. Class II anabolic androgenic steroids (AAS), including nandrolone, are rapidly becoming a widespread group of drugs used both clinically and illicitly. The illicit use of AAS is diffused among adolescent and bodybuilders because of their anabolic proprieties and their capacity to increase tolerance to exercise. This systematic review aims to focus on side effects related to illicit AAS abuse, evaluating the scientific literature in order to underline the most frequent side effects on AAS abusers’ bodies. Materials and Methods: A systematic review of the scientific literature was performed using the PubMed database and the keywords “nandrolone decanoate”. The inclusion criteria for articles or abstracts were English language and the presence of the following words: “abuse” or “adverse effects”. After applying the exclusion and inclusion criteria, from a total of 766 articles, only 148 were considered eligible for the study. Results: The most reported adverse effects (found in more than 5% of the studies) were endocrine effects (18 studies, 42%), such as virilization, gynecomastia, hormonal disorders, dyslipidemia, genital alterations, and infertility; cardiovascular dysfunctions (six studies, 14%) such as vascular damage, coagulation disorders, and arteriosus hypertension; skin disorders (five studies, 12%) such as pricking, acne, and skin spots; psychiatric and mood disorders (four studies, 9%) such as aggressiveness, sleep disorders and anxiety; musculoskeletal disorders (two studies, 5%), excretory disorders (two studies, 5%), and gastrointestinal disorders (two studies, 5%). Conclusions: Based on the result of our study, the most common adverse effects secondary to the abuse of nandrolone decanoate (ND) involve the endocrine, cardiovascular, skin, and psychiatric systems. These data could prove useful to healthcare professionals in both sports and clinical settings.

Adverse effects of high temperature on the development of reproductive organs in ‘Hakuho’ peach trees

2004 ◽  
Vol 79 (4) ◽  
pp. 533-537 ◽  
Author(s):  
Naoko Kozai ◽  
Kenji Beppu ◽  
Ryosuke Mochioka ◽  
Unaroj Boonprakob ◽  
Suranant Subhadrabandhu ◽  
...  
Keyword(s):  
High Temperature ◽  
Adverse Effects ◽  
Reproductive Organs ◽  
Peach Trees

scholarly journals Dose-Dependent Adverse Effects of Salinomycin on Male Reproductive Organs and Fertility in Mice

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69086 ◽  
Author(s):  
Olajumoke Omolara Ojo ◽  
Smrati Bhadauria ◽  
Srikanta Kumar Rath
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs ◽  
Male Reproductive Organs ◽  
Dose Dependent

scholarly journals Correction: Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0226872
Author(s):  
Olajumoke Omolara Ojo ◽  
Smrati Bhadauria ◽  
Srikanta Kumar Rath
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs ◽  
Male Reproductive Organs ◽  
Dose Dependent

scholarly journals Effect of feeding cottonseed cake on male fertility in rabbit

2015 ◽  
Vol 44 (1) ◽  
pp. 16-20
Author(s):  
A Kenfack ◽  
JK Chombong ◽  
F Ngoula ◽  
NB Vemo ◽  
AMM Tsambou ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Male Fertility ◽  
Histological Study ◽  
Reproductive Organs ◽  
Cottonseed Cake ◽  
Male Rabbit ◽  
Upper Limit ◽  
Significant Difference ◽  
Untreated Female ◽  
Effect Of Feeding

In order to study the effects of cottonseed cake on the fertility of the male rabbit, 60 animals (40 bucks and 20 does) were used. Males were 3 months old at the beginning of the essay, and the females were multiparous. Males were divided into 4 identical groups. Four diets containing 0, 6, 12 and 18% of cottonseed cake were formulated and randomly allotted to different groups of males. All the females received the same diet (6%). The treatment lasted for 90 days. At the end of that period, 5 males were sacrificed per lot and the rest were allowed to mate each with an untreated female before being sacrificed in turn. No significant difference (p>0.05) was observed among rations for the volume of testis and weight of reproductive organs. Histological study of the testes revealed no abnormality. In the presence of an untreated female, hundred percent of rabbits realized mounting and ejaculated whichever the cottonseed cake level. Nevertheless, the volume of the ejaculate was significantly (p>0.05) low in rabbit fed 6% cottonseed cake (0.86 vs 1.66, 12%). The spermatozoa concentration in the cauda epididymis was higher in rabbit given cottonseed cake than in control, although not significantly (p>0.05). The adverse effects of the toxicant contained in cottonseed cake occurred at 18% inclusion. The result showed that it is not possible to generalize the upper limit of inclusion of cottonseed cake in the ration formulation.DOI: http://dx.doi.org/10.3329/bjas.v44i1.23123             Bang. J. Anim. Sci. 2014. 44 (1): 16-20

scholarly journals Emergency contraception using progestin drugs in domestic cats

2020 ◽  
Vol 3 (2) ◽  
pp. 3-6
Author(s):  
A. Vasetska
Keyword(s):  
Adverse Effects ◽  
Sexual Function ◽  
Emergency Contraception ◽  
Companion Animals ◽  
Reproductive Organs ◽  
Reproductive Period ◽  
Reproductive Suppression ◽  
Stray Cats ◽  
Depot Injection ◽  
Depot Injections

Today, in conditions of strict quarantine, when it is not always possible to carry out surgery in cats, some methods of emergency drug contraception can be used. Over the years, many contraceptive medications have been developed for companion animals, but many secondary adverse effects have limited their use. However, in all species, the secondary adverse effects of progesterone-type drugs limit their use and vary depending on when treatment is given in relationship to the stage of the estrous cycle. An ideal non-surgical sterilant would be safe, effective, permanent, administered as a single injection and capable of being manufactured inexpensively. Contraceptives are used for cats, as a method of renewable fertility over time for breeding animals, as a method of suppressing sexual function for animals at risk for surgery, and to prevent over populations in stray cats. The use of non-surgical, safe and effective methods of suppression of sexual function in cats eliminates traumatization, anesthesia and complicated postoperative period in animals, which in some cases are impossible in the state of health, etc. The most common and affordable method of medical contraception is progestins, such as megestrol acetate, medroxyprogesterone acetate, proligestone (used orally or as a depot injection). These drugs are effective in inhibiting sexual function. Contraceptives for felids are available as implants, depot injections, and pills or liquid for oral administration, powder for mixing with food, or as vaccines. Regimens may differ according to the timing of first treatment, whether coinciding with the active reproductive period, preceding this period, or during anestrus. Ideally, the treatment regimen is initiated during anestrus to minimize the dose needed for reproductive suppression and to avert exposure to endogenous steroids that can cause lesions in reproductive organs.

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