scholarly journals Dose-Dependent Adverse Effects of Salinomycin on Male Reproductive Organs and Fertility in Mice

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69086 ◽  
Author(s):  
Olajumoke Omolara Ojo ◽  
Smrati Bhadauria ◽  
Srikanta Kumar Rath
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs ◽  
Male Reproductive Organs ◽  
Dose Dependent

scholarly journals Correction: Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0226872
Author(s):  
Olajumoke Omolara Ojo ◽  
Smrati Bhadauria ◽  
Srikanta Kumar Rath
Keyword(s):  
Adverse Effects ◽  
Reproductive Organs ◽  
Male Reproductive Organs ◽  
Dose Dependent

Intrauterine development, functions and diseases of male reproductive organs

2010 ◽  
Vol 151 (39) ◽  
pp. 1573-1579
Author(s):  
Ákos Jakobovits ◽  
Antal Jakobovits
Keyword(s):  
Reproductive Organs ◽  
Intrauterine Development ◽  
Male Reproductive Organs

A szerzők a központi idegrendszer, a tesztoszteron és származékainak szerepét tárgyalják a férfi nemi szervek méhen belüli fejlődésében. A férfi személyiségét meghatározó jellegzetességek először az emberi fejlődés magzati stádiumában jelentkeznek. Ezek kialakulása a gyermekkorban folytatódik. Pubertás után ezek növekvő mértékben válnak nyilvánvalóvá, és az egyén élete folyamán túlsúlyban maradnak. Az említett folyamatok mind a férfias fenotípust, mind a férfias magatartást befolyásolják. A tesztoszteron és származékai kontrollálják a férfi nemi szervek fejlődését. Hiányuk a női nemi jellegzetességek túlsúlyához vezet, a férfi nemi kromoszómakép ellenére. E jelenségek típusos példája a testicularis feminisatio klinikai képe. Jelen tanulmány különleges figyelmet szentel a reprodukciós szervek azon rendellenességeinek, amelyek a magzatokban ultrahanggal azonosíthatók. Ezen anomáliák legtöbbje antenatalisan hatásosan nem kezelhető. Azok a rendellenességek, amelyek a méhen kívüli életben sem gyógyíthatók, a terhességmegszakítás javallatát képezhetik, amennyiben ultrahangvizsgálattal a kora terhességben kimutathatók. Orv. Hetil., 2010, 39, 1573–1579.

The effect of Zotepine on productive and negative symptoms in schizophrenic patients

1988 ◽  
Vol 3 (2) ◽  
pp. 125-130
Author(s):  
D.M. Dieterle ◽  
M. Ackenheil ◽  
H.P. Kapfhammer ◽  
F. Müller-Spahn
Keyword(s):  
Adverse Effects ◽  
Negative Symptoms ◽  
Suicide Attempts ◽  
Positive Effects ◽  
Antipsychotic Efficacy ◽  
Schizophrenic Patients ◽  
Dose Dependent ◽  
Low Dosage ◽  
Motor Disturbances

RésuméZotepine was studied in 15 schizophrenic patients over a period of 28 days with regard to its antipsychotic efficacy, effect on negative schizophrenic symptoms, tolerability and adverse effects. Nine patients received Zotepine in a high dosage of 230 mg/die±52 mg, 6 patients in a low dosage of 168 mg/die ± 18 mg. Two patients receiving the high dosage dropped out after 21 days because of worsening of symptomatology and suicide attempts. Zotepine had rapid antipsychotic effects with sedative properties during the initial days of treatment. Minimal adverse effects and extra-pyramidal motor disturbances as well as dose-dependent positive effects on negative schizophrenie symptoms were found.

scholarly journals Failed prey or peculiar necrolysis? Isolated ammonite soft body from the Late Jurassic of Eichstätt (Germany) with complete digestive tract and male reproductive organs

2021 ◽  
Vol 140 (1) ◽  
Author(s):  
Christian Klug ◽  
Günter Schweigert ◽  
Helmut Tischlinger ◽  
Helmut Pochmann
Keyword(s):  
Digestive Tract ◽  
Late Jurassic ◽  
Reproductive Organs ◽  
Mantle Cavity ◽  
Soft Body ◽  
Exceptional Preservation ◽  
Attachment Structures ◽  
Male Reproductive Organs ◽  
Marine Basins

AbstractAmmonoid soft parts have been rarely described. Here, we document the soft parts of a perisphinctid ammonite from the early Tithonian of Wintershof near Eichstätt (Germany). This exceptional preservation was enabled by the special depositional conditions in the marine basins of the Solnhofen Archipelago. Here, we document this find and attempt to homologize its parts with various organs such as the digestive tract, reproductive organs, the mantle cavity with gills, and the hyponome, with differing degrees of reservation. Alternative interpretations are also taken into account. We suggest that the soft parts were separated from the conch either taphonomically (following necrolytical processes affecting the attachment structures) or during a failed predation, where a predator (fish or coleoid) removed the soft parts from the conch but then dropped them. This find is interesting because it adds to the knowledge of ammonite anatomy, which is normally hidden in the conch. The reproductive organs show traces of what might have been spermatophores, thus supporting the hypothesis that the microconchs represented the males.

scholarly journals Androgen action in the masculinization programming window and development of male reproductive organs

2010 ◽  
Vol 33 (2) ◽  
pp. 279-287 ◽  
Author(s):  
D. J. MacLeod ◽  
R. M. Sharpe ◽  
M. Welsh ◽  
M. Fisken ◽  
H. M. Scott ◽  
...  
Keyword(s):  
Reproductive Organs ◽  
Androgen Action ◽  
Male Reproductive Organs

scholarly journals LARVICIDAL ACTIVITY OFTITHONIA DIVERSIFOLIALEAF EXTRACT ONPERI-URBAN MOSQUITO LARVEA INABAKALIKI; ALTERNATIVE TO INSECTICIDE DEVELOPMENT.

2015 ◽  
Vol 7 (1) ◽  
pp. 1225-1228
Author(s):  
UHUO CA ◽  
OKEREKE CN ◽  
NWELE ED ◽  
OGBONNA S.U ◽  
NWANCHOR K.C ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Adverse Effects ◽  
Bioactive Compounds ◽  
Larvicidal Activity ◽  
Urban Areas ◽  
Insect Pests ◽  
Anopheles Mosquito ◽  
Mosquito Population ◽  
Mosquito Larvae ◽  
Dose Dependent

The bioassay activitiesofTithonia diversifolia leave extract was conducted on the larvae of Anopheles mosquito collected at peri-urban areas of Abakaliki Ebonyi State, using the concentrations of the extract in dilutions at 50/100ml, 40/100ml, 30/100ml and 20/100ml introduced with 10 Anopheles mosquito larvae each in four replicates and allowed for 3hrs. Mean mortality rate of the larvae were observed after the first hour, thus 30%, 10%, 05% and 0% respectively while in the 2nd hour were 60%, 40%, 20% and 10% and in the 3rd hour were 80%, 60%, 50% & 30% respectively. The result thus revealed that the treatment is dose dependent and that the studied specie has some bioactive compounds that can be exploited for insect pests control hence observed to be sensitive in anopheles mosquito larvae. Therefore Tithonia diversifolialeaf extract could be used as a bioassay for the control of mosquito due to its active properties as this has exhibited adverse effects on the larvae thereby reducing the mosquito population and thus reducing the malarious infection associated with the bite of mosquito.

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