scholarly journals Curcumin–β-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application

2014 ◽  
Vol 153 ◽  
pp. 361-370 ◽  
Author(s):  
Camila Sampaio Mangolim ◽  
Cristiane Moriwaki ◽  
Ana Claudia Nogueira ◽  
Francielle Sato ◽  
Mauro Luciano Baesso ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Photoacoustic Spectroscopy ◽  
Complex Stability ◽  
X Ray Diffraction ◽  
X Ray ◽  
Cyclodextrin Inclusion ◽  
Ft Ir ◽  
Cyclodextrin Inclusion Complex ◽  
Ft Raman

Effect of Ultra-High Pressure on the Characterization of Ursolic Acid/β-Cyclodextrin Inclusion Complex

2012 ◽  
Vol 424-425 ◽  
pp. 999-1002
Author(s):  
Feng Zhu Liu ◽  
Wei Zong
Keyword(s):  
High Pressure ◽  
Inclusion Complex ◽  
Ursolic Acid ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
X Ray ◽  
Ultra High Pressure ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

To study the characterization of ursolic acid (UA) and β- cyclodextrin(β-CD) inclusion complex which prepared by ultra-high pressure method. Inclusion complex of UA /β-CD was prepared at 100MPa and 500MPa. The inclusion complex was characterized by IR spectra, X-ray diffraction, Differential scanning calorimetry and Scanning electron microscope. It was testified that the inclusion complex was formed between β-CD and UA at ultra-high pressure conditions.

scholarly journals Comprehensive Characterisation of the Ketoprofen-β-Cyclodextrin Inclusion Complex Using X-ray Techniques and NMR Spectroscopy

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 4089
Author(s):  
Katarzyna Betlejewska-Kielak ◽  
Elżbieta Bednarek ◽  
Armand Budzianowski ◽  
Katarzyna Michalska ◽  
Jan K. Maurin
Keyword(s):  
Nmr Spectroscopy ◽  
Inclusion Complex ◽  
Crystal And Molecular Structure ◽  
Binding Constants ◽  
Nmr Studies ◽  
X Ray ◽  
Cyclodextrin Inclusion ◽  
Powder Samples ◽  
Cyclodextrin Inclusion Complex ◽  
Co Precipitation

Racemic ketoprofen (KP) and β-cyclodextrin (β-CD) powder samples from co-precipitation (1), evaporation (2), and heating-under-reflux (3) were analysed using X-ray techniques and nuclear magnetic resonance (NMR) spectroscopy. On the basis of NMR studies carried out in an aqueous solution, it was found that in the samples obtained by methods 1 and 2, there were large excesses of β-CD in relation to KP, 10 and 75 times, respectively, while the sample obtained by method 3 contained equimolar amounts of β-CD and KP. NMR results indicated that KP/β-CD inclusion complexes were formed and the estimated binding constants were approximately 2400 M−1, showing that KP is quite strongly associated with β-CD. On the other hand, the X-ray single-crystal technique in the solid state revealed that the (S)-KP/β-CD inclusion complex with a stoichiometry of 2:2 was obtained as a result of heating-under-reflux, for which the crystal and molecular structure were examined. Among the methods used for the preparation of the KP/β-CD complex, only method 3 is suitable.

scholarly journals Investigation of Cyclodextrin Inclusion Compounds Using FT-IR, SEM and X-Ray Diffraction

2016 ◽  
Vol 7 (3) ◽  
pp. 182-185 ◽  
Author(s):  
S. Zidane ◽  
◽  
A. Maiza ◽  
H. Bouleghlem ◽  
W. Herizi ◽  
...  
Keyword(s):  
Inclusion Compounds ◽  
X Ray Diffraction ◽  
X Ray ◽  
Cyclodextrin Inclusion ◽  
Ft Ir

scholarly journals Fabrication, Characterization, and Antimicrobial Activity, Evaluation of Low Silver Concentrations in Silver-Doped Hydroxyapatite Nanoparticles

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
A. Costescu ◽  
C. S. Ciobanu ◽  
S. L. Iconaru ◽  
R. V. Ghita ◽  
C. M. Chifiriuc ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Raman Spectroscopy ◽  
Hydroxyl Groups ◽  
Major Public Health Problem ◽  
Hydroxyapatite Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Ft Raman Spectroscopy ◽  
Ft Ir ◽  
Ft Raman

The aim of this study was the evaluation of(Ca10-xAgx)(PO4)6(OH)2nanoparticles (Ag:HAp-NPs) for their antibacterial and antifungal activity. Resistance to antimicrobial agents by pathogenic bacteria has emerged in the recent years as a major public health problem worldwide. In this paper, we report a comparison of the antimicrobial activity of low concentrations silver-doped hydroxyapatite nanoparticles. The silver-doped nanocrystalline hydroxyapatite powder was synthesized at 100°C in deionised water. The as-prepared Ag:Hap nanoparticles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), FT-IR, and FT-Raman spectroscopy. X-ray diffraction (XRD) studies demonstrate that powders obtained by coprecipitation at 100°C exhibit the apatite characteristics with good crystal structure, without any new phase or impurities found. FT-IR and FT-Raman spectroscopy revealed the presence of the various vibrational modes corresponding to phosphates and hydroxyl groups and the absence of any band characteristic to silver. The specific microbiological assays demonstrated that Ag:HAp-NPs exhibited antimicrobial features, but interacted differently with the Gram-positive, Gram-negative bacterial and fungal tested strains.

Rb2P2S6 – A New Alkali Thiophosphate: Crystal Structure and Vibrational Spectra of Rubidium Hexathiodiphosphate(V)

2006 ◽  
Vol 61 (9) ◽  
pp. 1049-1053 ◽  
Author(s):  
Mimoza Gjikaj ◽  
Claus Ehrhardt ◽  
Wolfgang Brockner
Keyword(s):  
Crystal Structure ◽  
Raman Spectroscopy ◽  
Group Analysis ◽  
Factor Group ◽  
X Ray Diffraction ◽  
Orthorhombic Space Group ◽  
X Ray ◽  
Ft Ir ◽  
Fir Spectra ◽  
Ft Raman

Abstract Single crystals of rubidium hexathiodiphosphate(V), Rb2P2S6, have been obtained and investigated by single crystal X-ray diffraction, and IR/FIR and Raman spectroscopy. The title compound crystallizes isotypically to the potassium, caesium and thallium analogues in the orthorhombic space group Immm (no. 71) with a = 8.485(3), b= 6.953(3), c =9.259(3 Å , and Z = 2, final R1= 0.0579 and wR2 = 0.0987. The crystal structure is characterized by discrete [P2S6]2− anions (edge-sharing double-tetrahedra) with D2h symmetry. Rubidium is coordinated by ten sulfur atoms forming a slightly distorted two-capped tetragonal prism with a coordination number CNRb 10. The FT-Raman and FT-IR/FIR spectra have been recorded and a factor group analysis was carried out.

scholarly journals A molecular inclusion complex of atenolol with 2-hydroxypropyl-β-cyclodextrin: The production and characterization thereof

2007 ◽  
Vol 72 (8-9) ◽  
pp. 737-746 ◽  
Author(s):  
Vesna Nikolic ◽  
Ljubisa Nikolic ◽  
Mihajlo Stankovic ◽  
Agnes Kapor ◽  
Mirjana Popsavin ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
1H Nmr ◽  
13C Nmr ◽  
Chemical Shifts ◽  
13C Nmr Spectroscopy ◽  
X Ray Diffraction ◽  
X Ray ◽  
Molecular Inclusion ◽  
Ft Ir ◽  
Diffraction Patterns

The molecular inclusion complex of atenolol with 2-hydroxypropyl-?-cyclodextrin was synthesized using the coprecipitation method. The complex obtained was characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopy, as well as by DSC and X-ray diffraction analysis. The DSC analysis confirmed the existence of the complex with the endothermic atenolol melting peak at about 155?C disappearing. The X-ray diffraction patterns of the complex and 2-hydroxypropyl-?-cyclodextrin were very similar, thus confirming the complete inclusion of the atenolol molecule within the cavity of the 2-hydroxypropyl-?-cyclodextrin. The peaks originating from atenolol were completely absent in the diffractogram of the complex. 1H-NMR and 13C-NMR spectra showed certain changes in the chemical shifts of protons and C atoms from atenolol and 2-hydroxypropyl-?-cyclodextrin, indicating that a complex had been formed and also which protons participated in the hydrogen bonds which formed the complex. The atenolol solubility in water was improved (254 mg complex cm-3, i.e., 37.5 mg atenolol cm-3), and in pH 3 HCl solution (251 mg complex cm-3, i.e., 37 mg atenolol cm-3) when compared to pure atenolol, and even when compared to the atenolol complex with ?-cyclodextrin. The increased solubility ensures greater bioavailability of the active component and, due to the low solubility, significantly corrects for the lack of the basic active substance and, simultaneously, increases its overall therapeutic effect, combined with reduced side effects. .

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