The C-reactive protein of tongue sole Cynoglossus semilaevis is an acute phase protein that interacts with bacterial pathogens and stimulates the antibacterial activity of peripheral blood leukocytes

2013 ◽  
Vol 34 (2) ◽  
pp. 623-631 ◽  
Author(s):  
Mo-fei Li ◽  
Cheng Chen ◽  
Jun Li ◽  
Li Sun
Keyword(s):  
Antibacterial Activity ◽  
Peripheral Blood ◽  
Acute Phase Protein ◽  
Cynoglossus Semilaevis ◽  
Peripheral Blood Leukocytes ◽  
C Reactive Protein ◽  
Blood Leukocytes ◽  
Reactive Protein ◽  
Tongue Sole ◽  
Phase Protein

scholarly journals THE LIVER AS THE SITE OF C-REACTIVE PROTEIN FORMATION

1966 ◽  
Vol 123 (2) ◽  
pp. 365-378 ◽  
Author(s):  
J. Hurlimann ◽  
G. J. Thorbecke ◽  
G. M. Hochwald
Keyword(s):  
Amino Acid ◽  
Serum Proteins ◽  
Acute Phase Protein ◽  
Human Beings ◽  
C Reactive Protein ◽  
Amino Acid Incorporation ◽  
Reactive Protein ◽  
Acid Incorporation ◽  
Phase Protein

The site of formation of C-reactive protein (CxRP, CRP) has been studied with tissues from rabbits, monkeys, and human beings. Rabbits and monkeys were stimulated to produce the acute phase protein by injection of turpentine, croton oil, endotoxin, paratyphoid-typhoid vaccine, or pneumococci. C14-amino acid incorporation in vitro was demonstrated by means of autoradiography of immunoelectrophoretic patterns made with culture fluids. It was found that among many different tissues tested liver was the only tissue which incorporated C14-lysine and isoleucine into CxRP or CRP. Only livers taken 16 to 24 hr after various stimuli were active; livers from normal animals or from animals killed 3 to 9 hr after stimulation did not produce detectable amounts of CxRP. Inflamed muscle from the injection site did not show C14-amino acid incorporation into CxRP. Several human tissues were also cultured, and a few liver cultures found to contain labeled CRP. The formation of CxRP or CRP by the liver was always accompanied by enhanced C14-amino acid incorporation into other serum proteins, but the reverse was not always found.

Serum Amyloid A and C-Reactive Protein Concentrations Are Differently Associated with Markers of Autoimmunity in Patients with Primary Sjögren’s Syndrome

2009 ◽  
Vol 36 (11) ◽  
pp. 2487-2490 ◽  
Author(s):  
MARJA PERTOVAARA ◽  
JUULIA JYLHÄVÄ ◽  
HANNU UUSITALO ◽  
JUHANI PUKANDER ◽  
HEIKKI HELIN ◽  
...  
Keyword(s):  
Acute Phase ◽  
Serum Amyloid A ◽  
Acute Phase Protein ◽  
Inverse Correlation ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Amyloid A ◽  
Phase Protein ◽  
Sicca Symptoms ◽  
Protein Serum

Objective.Primary Sjögren’s syndrome (pSS) is an autoimmune disease in which the concentration of the acute-phase protein serum C-reactive protein (CRP) is low. We investigated whether levels of another acute-phase protein, serum amyloid A (SAA), are increased in patients with pSS and whether the immunological markers in patients with pSS are associated with variation in SAA levels.Methods.Serum SAA concentrations were measured by ELISA in 74 patients with pSS and in 56 control subjects with sicca symptoms.Results.Median SAA levels did not differ significantly between patients with pSS and subjects with sicca symptoms. In patients with pSS SAA concentrations correlated significantly with age, leukocyte count, CRP, interleukin 6, and C4. Unlike CRP, there was a significant inverse correlation between SAA and serum IgG levels and anti-SSA antibody titers, as well as a trend towards an inverse correlation between SAA and antinuclear antibody and rheumatoid factor titers.Conclusion.Our data imply that high SAA production could constitute a protective element in pSS: high SAA levels inhibit in particular various signs of B cell hyperreactivity, i.e., IgG and autoantibody production.

scholarly journals AN IMMUNOLOGICAL AND ELECTROPHORETIC COMPARISON OF THE ANTIBODY TO C POLYSACCHARIDE AND THE C-REACTIVE PROTEIN OF ACUTE PHASE SERUM

1943 ◽  
Vol 77 (2) ◽  
pp. 97-110 ◽  
Author(s):  
Ely Perlman ◽  
Jesse G. M. Bullowa ◽  
Ruth Goodkind
Keyword(s):  
Acute Phase ◽  
Gamma Globulin ◽  
Acute Phase Protein ◽  
Precipitation Reaction ◽  
Globulin Fraction ◽  
C Reactive Protein ◽  
C Protein ◽  
Reactive Protein ◽  
Phase Protein ◽  
Acute Phase Serum

1. Studies of the precipitation reaction of C polysaccharide with C protein, and of C polysaccharide with C antibody are reported. The similarity between these two systems in this respect is demonstrated. 2. The differences between C protein and C antibody are emphasized. The differences between this protein and antibodies in general have been reported previously by others. 3. Electrophoretic studies show that C antibody is in the gamma globulin fraction of serum whereas C protein migrates with the alpha1 globulin fraction of acute phase protein.

Biominetic-mineralized multifunctional nanoflowers for anodic-stripping voltammetric immunoassay of rehabilitation-related proteins

The Analyst ◽  
2021 ◽  
Author(s):  
Fan Cai ◽  
Jun Wang ◽  
Yao Lin ◽  
Dianping Tang
Keyword(s):  
Cerebral Infarction ◽  
Acute Phase ◽  
Acute Phase Protein ◽  
Acute Cerebral Infarction ◽  
Neurological Rehabilitation ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Anodic Stripping ◽  
Phase Protein ◽  
Related Proteins

C-reactive protein (CRP; an acute-phase protein) in patients with initial acute cerebral infarction neurological rehabilitation prediction has a significant correlation. Herein, a simple and sensitive anodic-stripping voltammetric (ASV) immunosensing system...

C-reactive protein: a predominant LPS-binding acute phase protein responsive to Pseudomonas infection

2004 ◽  
Vol 10 (3) ◽  
pp. 163-174 ◽  
Author(s):  
Patricia M.L. Ng ◽  
Zhenxiao Jin ◽  
Sandra S.H. Tan ◽  
Bow Ho ◽  
Jeak L. Ding
Keyword(s):  
Acute Phase ◽  
Acute Phase Protein ◽  
Protein A ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Phase Protein ◽  
Pseudomonas Infection ◽  
Lps Binding
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