Vancomycin-resistant enterococci in Iran: A systematic review and meta-analysis of non-clinical studies

Gene Reports ◽  
2021 ◽  
pp. 101265
Author(s):  
Fereshteh Hasanpour ◽  
Zohreh Neyestani ◽  
Mohsen Arzanlou ◽  
Eslam Moradi-Asl ◽  
Amirhossein Sahebkar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Studies ◽  
Meta Analysis ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

scholarly journals Vancomycin-Resistant Enterococci (VRE) in Nigeria: The First Systematic Review and Meta-Analysis

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 565
Author(s):  
Yusuf Wada ◽  
Azian Binti Harun ◽  
Chan Yean Yean ◽  
Abdul Rahman Zaidah
Keyword(s):  
Systematic Review ◽  
Publication Bias ◽  
Meta Analysis ◽  
Forest Plot ◽  
Funnel Plot ◽  
Vancomycin Resistant Enterococci ◽  
Pooled Prevalence ◽  
Vancomycin Resistant ◽  
Meta Regression ◽  
Leave One Out

Vancomycin-Resistant Enterococci (VRE) are on the rise worldwide. Here, we report the first prevalence of VRE in Nigeria using systematic review and meta-analysis. International databases MedLib, PubMed, International Scientific Indexing (ISI), Web of Science, Scopus, Google Scholar, and African journals online (AJOL) were searched. Information was extracted by two independent reviewers, and results were reviewed by the third. Two reviewers independently assessed the study quality using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) checklist. OpenMeta analyst was used. The random effect was used, and publication bias was assessed using a funnel plot. Between-study heterogeneity was assessed, and the sources were analysed using the leave-one-out meta-analysis, subgroup analysis, and meta-regression. Nineteen studies met the eligibility criteria and were added to the final meta-analysis, and the study period was from 2009–2018. Of the 2552 isolates tested, 349 were VRE, and E. faecalis was reported the most. The pooled prevalence of VRE in Nigeria was estimated at 25.3% (95% CI; 19.8–30.8%; I2 = 96.26%; p < 0.001). Between-study variability was high (t2 = 0.011; heterogeneity I2 = 96.26% with heterogeneity chi-square (Q) = 480.667, degrees of freedom (df) = 18, and p = 0.001). The funnel plot showed no publication bias, and the leave-one-out forest plot did not affect the pooled prevalence. The South-East region had a moderate heterogeneity though not significant (I2 = 51.15%, p = 0.129). Meta-regression showed that all the variables listed contributed to the heterogeneity except for the animal isolate source (p = 0.188) and studies that were done in 2013 (p = 0.219). Adherence to proper and accurate antimicrobial usage, comprehensive testing, and continuous surveillance of VRE are required.

scholarly journals Sex differences in vancomycin-resistant enterococci bloodstream infections—a systematic review and meta-analysis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Carlos L. Correa-Martínez ◽  
Franziska Schuler ◽  
Stefanie Kampmeier
Keyword(s):  
Systematic Review ◽  
Sex Differences ◽  
Meta Analysis ◽  
Bloodstream Infections ◽  
Prevalence Ratio ◽  
Risk Of Bias ◽  
Control Measures ◽  
Bias Assessment ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

Abstract Background Vancomycin-resistant enterococci (VRE) have emerged in the healthcare setting worldwide. Infections with these pathogens, i.e., bloodstream infections (BSI), are accompanied with an impaired patient outcome. Diverse factors comprising patient characteristics, therapeutic strategies, and infection control measures are positively or negatively associated with VRE BSI occurrence. However, whether sex-specific differences influence the frequency of VRE BSI is yet unknown. The aim of this systematic review was to comprehensively summarize and analyze sex prevalence in VRE BSI patients. Main text A systematic search for relevant articles was conducted in PubMed and Web of Science. After screening for eligibility, data extraction from included articles and risk of bias assessment were processed. The prevalence of male/female sex in VRE BSI patients and 95% CI were calculated for each study and summarized as pooled estimated effect. In total, nine articles met the inclusion criteria. Risk of bias assessment resulted in low (six studies) to moderate bias (three studies). The pooled prevalence of male patients suffering from VRE BSI was 59% resulting in a 1.4 male/female prevalence ratio. Conclusions Current literature suggests sex differences with male preference (59%) in the distribution of VRE BSI cases. Further primary studies should address the question of male-specific factors favoring the enhanced frequency of VRE BSI.

scholarly journals A systematic review and meta-analysis on the prevalence of vancomycin-resistant enterococci (VRE) among Nigerians

2021 ◽  
Vol 6 (1) ◽  
pp. e125
Author(s):  
Oluwatosin Qawiyy Orababa ◽  
Jeffry Difiye Soriwei ◽  
Samuel Oluwamayowa Akinsuyi ◽  
Utibeima Udo Essiet ◽  
Olusola Michael Solesi
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

Prevalence of vancomycin‐resistant enterococci in Asia—A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Suraj Shrestha ◽  
Sanjeev Kharel ◽  
Sushan Homagain ◽  
Roshan Aryal ◽  
Shyam Kumar Mishra
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Vancomycin Resistant Enterococci ◽  
Vancomycin Resistant

scholarly journals Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic review and meta-analysis of clinical studies

2021 ◽  
pp. 174248
Author(s):  
Kiarash Saleki ◽  
Shakila Yaribash ◽  
Mohammad Banazadeh ◽  
Ehsan Hajihosseinlou ◽  
Mahdi Gouravani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Studies ◽  
Interferon Therapy ◽  
Meta Analysis
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