Frailty state transitions among non-frail and vulnerable older adults: Does mobility performance really matter?

2021 ◽  
Vol 42 (6) ◽  
pp. 1367-1372
Author(s):  
Isabela T. Machado de Jesus ◽  
Fabiana de Souza Orlandi ◽  
Grace Angélica de Oliveira Gomes ◽  
Karina Gramani Say ◽  
Letícia Pimenta Costa Guarisco ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Joe Nocera ◽  
Thomas W. Buford ◽  
Todd M. Manini ◽  
Kelly Naugle ◽  
Christiaan Leeuwenburgh ◽  
...  

A primary focus of longevity research is to identify prognostic risk factors that can be mediated by early treatment efforts. To date, much of this work has focused on understanding the biological processes that may contribute to aging process and age-related disease conditions. Although such processes are undoubtedly important, no current biological intervention aimed at increasing health and lifespan exists. Interestingly, a close relationship between mobility performance and the aging process has been documented in older adults. For example, recent studies have identified functional status, as assessed by walking speed, as a strong predictor of major health outcomes, including mortality, in older adults. This paper aims to describe the relationship between the comorbidities related to decreased health and lifespan and mobility function in obese, older adults. Concurrently, lifestyle interventions, including diet and exercise, are described as a means to improve mobility function and thereby limit the functional limitations associated with increased mortality.


2016 ◽  
Vol Volume 11 ◽  
pp. 1579-1587 ◽  
Author(s):  
Sigrid Mueller-Schotte ◽  
Nienke Bleijenberg ◽  
Yvonne T. van der Schouw ◽  
Marieke J. Schuurmans

2004 ◽  
Vol 81 (5) ◽  
pp. 298-307 ◽  
Author(s):  
KATHLEEN A. TURANO ◽  
AIMEE T. BROMAN ◽  
KAREN BANDEEN-ROCHE ◽  
BEATRIZ MUNOZ ◽  
GARY S. RUBIN ◽  
...  

Author(s):  
Carl-Philipp Jansen ◽  
Nima Toosizadeh ◽  
M. Jane Mohler ◽  
Bijan Najafi ◽  
Christopher Wendel ◽  
...  

Abstract Background In older adults, the linkage between laboratory-assessed ‘motor capacity’ and ‘mobility performance’ during daily routine is controversial. Understanding factors moderating this relationship could help developing more valid assessment as well as intervention approaches. We investigated whether the association between capacity and performance becomes evident with transition into frailty, that is, whether frailty status moderates their association. Methods We conducted a cross-sectional analysis of the observational Arizona Frailty Cohort Study (ClinicalTrials.gov identifier: NCT01880229) in a community-dwelling cohort in Tucson, Arizona. Participants were N = 112 older adults aged 65 years or older who were categorized as non-frail (n = 40), pre-frail (n = 53) or frail (n = 19) based on the Fried frailty index. Motor capacity was quantified as normal (NWS) and fast walking speed (FWS). Mobility performance was quantified as 1) cumulated physical activity (PA) time and 2) everyday walking performance (average steps per walking bout; maximal number of steps in one walking bout), measured by a motion sensor over a 48 h period. Hierarchical linear regression analyses were performed to evaluate moderation effects. Results Unlike in non-frail persons, the relationship between motor capacity and mobility performance was evident in pre-frail and frail persons, confirming our hypothesis. A moderating effect of frailty status was found for 1) the relationship between both NWS and FWS and maximal number of steps in one bout and 2) NWS and the average steps per bout. No moderation was found for the association between NWS and FWS with cumulated PA. Conclusion In pre-frail and frail persons, motor capacity is associated with everyday walking performance, indicating that functional capacity seems to better represent mobility performance in this impaired population. The limited relationship found in non-frail persons suggests that other factors account for their mobility performance. Our findings may help to inform tailored assessment approaches and interventions taking into consideration a person’s frailty status.


2003 ◽  
Vol 58 (8) ◽  
pp. M734-M739 ◽  
Author(s):  
N. B. Alexander ◽  
D. R. Dengel ◽  
R. J. Olson ◽  
K. M. Krajewski

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 26-26
Author(s):  
Mette Merete Pedersen ◽  
Janne Petersen ◽  
Ove Andersen ◽  
Efrat Shadmi ◽  
Ksenya Shulyaev ◽  
...  

Abstract Low levels of in-hospital mobility and excessive bed rest are widely described across the globe as a major risk factor for hospital associated disabilities. Different predictors of in-hospital and post-discharge mobility limitations have been proposed across studies, including age, admission diagnosis, physical performance, cognitive impairment, performance of activities of daily living, and length of stay. However, it is unknown whether similar risk factors across countries are associated with in-hospital mobility given different mobility measurement methods, variations in measurement of predictors and differences in populations studied. In the current study, we investigated the relationship between in-hospital mobility and a set of similar risk factors in functionally independent older adults (65+) hospitalized in acute care settings in Israel (N=206) and Denmark (N=113). In Israel, mobility was measured via ActiGraph and in Denmark by ActivPal for up to seven hospital days. Parallel analysis of covariance (ANCOVA) in each sample showed that community-mobility before hospitalization, mobility performance at admission and length of stay were associated with in-hospital mobility in both countries, whereas age and self-reported health status were associated with mobility only in Denmark. This comparison indicates that despite slightly different measurement approaches, similar risks are attributed to older adults’ low in-hospital mobility and emphasizes the contribution of commonly used pre-hospitalization mobility measures as strong and consistent risk factors. This knowledge can support a better understanding of the need of both standard risk assessments and country-based tailored approaches.


2018 ◽  
Vol 18 (11) ◽  
pp. 1549-1555 ◽  
Author(s):  
Mark Q Thompson ◽  
Olga Theou ◽  
Robert J Adams ◽  
Graeme R Tucker ◽  
Renuka Visvanathan

Author(s):  
Toshikazu Kawagoe ◽  
Maki Suzuki ◽  
Shu Nishiguchi ◽  
Nobuhito Abe ◽  
Yuki Otsuka ◽  
...  

2018 ◽  
Vol 75 ◽  
pp. 119-124 ◽  
Author(s):  
Paolo Riccardo Brustio ◽  
Emanuela Rabaglietti ◽  
Sabrina Formica ◽  
Monica Emma Liubicich

2000 ◽  
Vol 48 (11) ◽  
pp. 1408-1413 ◽  
Author(s):  
Neil B. Alexander ◽  
Kenneth E. Guire ◽  
Darryl G. Thelen ◽  
James A. Ashton-Miller ◽  
Albert B. Schultz ◽  
...  

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