Mo1360 A New Tool for Pre-Colonoscopy Dying of the Colonic Mucosa With Oral Multi Matrix Release Technology (MMX®)-Released Methylene Blue: A Preliminary Study of Absorption, Bioavailability and Toxicity

2011 ◽  
Vol 73 (4) ◽  
pp. AB318
Author(s):  
Alessandro Repici ◽  
Luigi Moro ◽  
Luca Loprete ◽  
Cesare Hassan ◽  
Silvio Danese
Keyword(s):  
Methylene Blue ◽  
Colonic Mucosa ◽  
Preliminary Study ◽  
Matrix Release

scholarly journals Antimicrobial effect of methylene blue formulations with oxygen carrier at different pHs: preliminary study

2019 ◽  
Vol 22 (1) ◽  
pp. Process
Author(s):  
Jessica Klöckner Knorst ◽  
Gabriela Scarton Barriquello ◽  
Marcos Antônio Villetti ◽  
Roberto Christ Vianna Santos ◽  
Karla Zanini Kantorski
Keyword(s):  
Methylene Blue ◽  
Pseudomonas Aeruginosa ◽  
Photodynamic Therapy ◽  
Oxygen Carrier ◽  
Statistical Significance ◽  
Antimicrobial Effect ◽  
Control Group ◽  
Preliminary Study ◽  
Post Hoc ◽  
Multispecies Biofilms

Objective: Evaluate methylene blue (MB) formulations containing oxygen carrier at different pHs in antimicrobial photodynamic therapy (aPDT). Material and Methods: Biofilms of Pseudomonas aeruginosa PA01 formed over acrylics specimens during five days were treated with aPDT using different formulations: MB/pH 7.4; MB/pH 5.6; MB/carrier pH 7.4; MB/carrier pH 5.6. Biofilms not exposed to treatment were used as a control. Blind examiner for the experimental groups performed the counting of colonies per ml suspension (CFU/ml). Two-way ANOVA was used to determine the effect of factors solvent (carrier vs water) and pH (7.4 vs 5.6). One-way ANOVA and post-hoc Tukey’s test was used to evaluate differences among the five groups (control; MB/carrier pH 7.4; MB pH 7.4; MB/carrier pH 5.6; MB pH 5.6). The Statistics 8.0 software was used (P<0.05). Results: All of photodynamic therapy groups showed significant reduction in P. aeruginosa compared to the control group. The solvent factor was not significant (P=0.18), while the pH factor presented statistical significance (P=0.01). When the carrier was used, MB formulation at pH 7.4 presented a statistically greater reduction of P. aeruginosa than the formulation with pH 5.6. Conclusion: The PDT using methylene blue formulations with oxygen carrier demonstrated potential for the treatment of localized infections by P. aeruginosa. MB formulations with oxygen carrier and pH 7.4 resulted in higher antimicrobial effect and should be considered for future studies with multispecies biofilms.  KeywordsAntimicrobial photodynamic therapy; biofilm; laser; Pseudomonas aeruginosa.

scholarly journals Preliminary Study of Photocatalytic Degradation of Methylene Blue Dye using Magnetic Alginate/Fe3O4 (Alg/Fe3O4) Nanocomposites

2019 ◽  
Vol 19 (1) ◽  
pp. 26-34
Author(s):  
Ganjar Fadillah ◽  
Muhamad Allan Serunting
Keyword(s):  
Electron Microscopy ◽  
Methylene Blue ◽  
Irradiation Time ◽  
Average Diameter ◽  
Molar Ratio ◽  
Blue Dye ◽  
Natural Polymers ◽  
Transmission Electron ◽  
Coating Method ◽  
Preliminary Study

The Magnetic compound, Fe3O4, is one of the compounds that is easily hydrolyzed and oxidized. A coating method was presented in this study to prevent the process. The modifications of Fe3O4 were carried out by supporting alginate as natural polymers on the surface of Fe3O4. Preparation of magnetic alginate/Fe3O4 (Alg/Fe3O4) nanocomposite has been successfully synthesized. Alg/Fe3O4 material was synthesized using the coprecipitation method with Fe2+; Fe3+ (with molar ratio 1:2) and alginate 1% as precursors. Synthesized Alg/Fe3O4 nanoparticles were characterized by Fourier Transform Infrared Spectroscopy (FTIR), DelsaTM Nano C Particle Analyzer, Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and Energy Dispersive Spectroscopy (EDS). The Alg/Fe3O4 has an average diameter of 13.70 nm. Photodegradation test of synthetic methylene blue (MB) dye was found at pH 5.0 and irradiation time under UV245 for 60 minutes. The degradation results showed that the percentage of MB dye removal reached more than 90%.

scholarly journals Preliminary Study Into the Decolorization of Selected Dyes By the Ozone Application

2021 ◽  
Vol 29 (48) ◽  
pp. 37-44
Author(s):  
Kristína Gerulová ◽  
Zuzana Sanny ◽  
Alexandra Kucmanová ◽  
Eva Buranská
Keyword(s):  
Methylene Blue ◽  
Chemical Composition ◽  
Congo Red ◽  
Small Dose ◽  
Sewage Treatment ◽  
Synthetic Dyes ◽  
Colour Removal ◽  
Sewage Treatment Plants ◽  
Decolorization Rate ◽  
Preliminary Study

Abstract Synthetic dyes widely used in many kinds of industry affect the colour of wastewater when released to environment due to insufficient treatment in typical sewage treatment plants. Only a small dose of those dyes may significantly affect colour of water and, according to the chemical composition, may pose risks to wildlife and humans. In the research described in this study, decolorization of three various dyes was investigated. Since colour removal of Congo Red such as Methylene blue using ozone have been reported by several authors, and the literature on Naphthol Green B is rather limited, in the present study we compare the decolorization rate of CR, MB and NGB. The colour removal occurred quickly and more than 90% of colour reduction was achieved within 3-6 minutes throughout all tested pH of the solution.

scholarly journals Endonyx toenail onychomycosis caused by Trichophyton rubrum: treatment with photodynamic therapy based on methylene blue dye

2013 ◽  
Vol 88 (6) ◽  
pp. 1019-1021 ◽  
Author(s):  
Linton Wallis Figueiredo Souza ◽  
Simone Vilas Trancoso Souza ◽  
Ana Cristina de Carvalho Botelho
Keyword(s):  
Aqueous Solution ◽  
Methylene Blue ◽  
Photodynamic Therapy ◽  
Energy Density ◽  
Light Emission ◽  
Trichophyton Rubrum ◽  
Blue Dye ◽  
Methylene Blue Dye ◽  
Preliminary Study

This study shows the effectiveness of photodynamic therapy based on methylene blue dye for the treatment of endonyx toenail onychomycosis. Four patients with endonyx onychomycosis caused by Trichophyton rubrum were treated with 2% methylene blue aqueous solution irradiated with light emission diode at 630 nm and an energy density of 36 J/cm2 for 6 months at 2-week intervals. The preliminary study showed the effectiveness of this therapy in the treatment of endonyx onychomycosis, and also indicated that the disease can be caused by T. rubrum.

Comparison of methylene blue-directed biopsies and conventional biopsies in the detection of intestinal metaplasia and dysplasia in Barrett's esophagus: A preliminary study

2001 ◽  
Vol 54 (3) ◽  
pp. 294-301 ◽  
Author(s):  
John M. Wo ◽  
Mukunda B. Ray ◽  
Stephanie Mayfield-Stokes ◽  
Ghassan Al-Sabbagh ◽  
Fadi Gebrail ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Intestinal Metaplasia ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Preliminary Study

scholarly journals Preliminary Study of Photocatalytic Degradation of Methylene Blue Dye using Magnetic Alginate/Fe3O4 (Alg/Fe3O4) Nanocomposites

2019 ◽  
Vol 19 (1) ◽  
pp. 26-34
Author(s):  
Ganjar Fadillah ◽  
Muhamad Allan Serunting
Keyword(s):  
Electron Microscopy ◽  
Methylene Blue ◽  
Irradiation Time ◽  
Average Diameter ◽  
Molar Ratio ◽  
Blue Dye ◽  
Natural Polymers ◽  
Transmission Electron ◽  
Coating Method ◽  
Preliminary Study

The Magnetic compound, Fe3O4, is one of the compounds that is easily hydrolyzed and oxidized. A coating method was presented in this study to prevent the process. The modifications of Fe3O4 were carried out by supporting alginate as natural polymers on the surface of Fe3O4. Preparation of magnetic alginate/Fe3O4 (Alg/Fe3O4) nanocomposite has been successfully synthesized. Alg/Fe3O4 material was synthesized using the coprecipitation method with Fe2+; Fe3+ (with molar ratio 1:2) and alginate 1% as precursors. Synthesized Alg/Fe3O4 nanoparticles were characterized by Fourier Transform Infrared Spectroscopy (FTIR), DelsaTM Nano C Particle Analyzer, Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and Energy Dispersive Spectroscopy (EDS). The Alg/Fe3O4 has an average diameter of 13.70 nm. Photodegradation test of synthetic methylene blue (MB) dye was found at pH 5.0 and irradiation time under UV245 for 60 minutes. The degradation results showed that the percentage of MB dye removal reached more than 90%.

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