Endoscopic resection: Comparable with surgical resection for treating small-sized gastric GI stromal tumors?

AbstractLittle is known about the incidence of metachronous advanced neoplasia (AN) following resection of submucosal invasive colorectal cancer (SM-CRC). Here, we aimed to assess the occurrence of metachronous AN following SM-CRC resection. We retrospectively reviewed consecutive patients who underwent SM-CRC resection at an academic medical center between 2005 and 2013. Among 343 patients, 250 (72.9%) underwent surgical resection or endoscopic resection followed by surgical resection and 93 (27.1%) underwent only endoscopic resection. During a median follow-up period of 61.5 months, the overall incidence of metachronous AN was 7.6%, and the cumulative incidence at 5 years was 6.1%. The cumulative incidence was significantly higher in the endoscopic resection group than in surgical resection group, in patients with colonic disease than in those with rectal disease, and in patients with synchronous AN than in those without. Multivariate analysis revealed that synchronous AN was the only significant risk factor for metachronous AN (HR 4.35; 95% CI 1.88–10.1). These findings imply that depending on synchronous AN, a surveillance protocol following SM-CRC resection can be changed for better detection of metachronous AN.

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Endoscopic Resection Versus Surgical Resection for Early Gastric Cancer

Medicine ◽

10.1097/md.0000000000001649 ◽

2015 ◽

Vol 94 (43) ◽

pp. e1649 ◽

Cited By ~ 15

Author(s):

Weili Sun ◽

Xiao Han ◽

Siyuan Wu ◽

Chuanhua Yang

Keyword(s):

Gastric Cancer ◽

Early Gastric Cancer ◽

Surgical Resection ◽

Endoscopic Resection

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Endoscopic resection of gastric gastrointestinal stromal tumors

Translational Gastroenterology and Hepatology ◽

10.21037/tgh.2017.12.03 ◽

2017 ◽

Vol 2 (12) ◽

pp. 115-115 ◽

Cited By ~ 20

Author(s):

Yuyong Tan ◽

Linna Tan ◽

Jiaxi Lu ◽

Jirong Huo ◽

Deliang Liu

Keyword(s):

Endoscopic Resection ◽

Gastrointestinal Stromal Tumors ◽

Stromal Tumors

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Clinical Overview of GIST and Its Latest Management by Endoscopic Resection in Upper GI: A Literature Review

Gastroenterology Research and Practice ◽

10.1155/2018/6864256 ◽

2018 ◽

Vol 2018 ◽

pp. 1-9 ◽

Cited By ~ 7

Author(s):

Cicilia Marcella ◽

Rui Hua Shi ◽

Shakeel Sarwar

Keyword(s):

Endoscopic Resection ◽

Gastrointestinal Stromal Tumors ◽

En Bloc Resection ◽

Bloc Resection ◽

En Bloc ◽

Endoscopic Techniques ◽

Stromal Tumors ◽

Upper Gi ◽

Risk Of Malignancy

Aims. To review the clinical presentation, diagnosis, assessment of risk of malignancy, and recent advances in management (mainly focusing on the role of endoscopic resection) of gastrointestinal stromal tumors (GISTs) in upper GI.Method. We searched Embase, Web of science, and PubMed databases from 1993 to 2018 by using the following keywords: “gastrointestinal stromal tumors,” “GIST,” “treatment,” and “diagnosis.” Additional papers were searched manually from references of the related articles.Findings. The improvement of endoscopic techniques in treating upper gastrointestinal subepithelial tumors especially gastrointestinal tumors has reduced the need for invasive surgery in patients unfit for surgery. Many studies have concluded that modified endoscopic treatments are effective and safe. These treatments permit minimal tissue resection, better dissection control, and high rates of en bloc resection with an acceptable rate of complications.

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