scholarly journals Antifungal activity and toxicity studies of flavanones isolated from Tessaria dodoneifolia aerial parts

Heliyon ◽  
2020 ◽  
Vol 6 (10) ◽  
pp. e05174
Author(s):  
José R. Soberón ◽  
Melina A. Sgariglia ◽  
José A. Carabajal Torrez ◽  
Franco A. Aguilar ◽  
Edgardo J.I. Pero ◽  
...  
2017 ◽  
Vol 203 ◽  
pp. 233-240 ◽  
Author(s):  
José R. Soberón ◽  
Melina A. Sgariglia ◽  
Ana C. Pastoriza ◽  
Estela M. Soruco ◽  
Sebastián N. Jäger ◽  
...  

2006 ◽  
Vol 1 (9) ◽  
pp. 1934578X0600100
Author(s):  
Ahmed A. Mahmoud ◽  
Shar S. Al-Shihry

A new ionone glucoside, (-)(4R*, 5R*)-5-(β-D-glucopyranosyloxymethyl)-4-hydroxy-3,5-dimethyl-4-((E)-3-oxobut-1-enyl)cyclohex-2-enone (biebersteiniside) (1), in addition to four known compounds, 6-epiroseoside (2), ascaridole (3), strictic acid (4) and centipedic acid (5) have been isolated from the aerial parts of Achillea biebersteinii Afan. The structures were determined from extensive 500 MHz NMR 1D (1H and 13C NMR) and 2D (1H-1H COSY, HMQC, HMBC and NOESY) spectroscopic data. Compounds 2–5 are reported for the first time from this plant. In addition, compounds 1a and 3–5 showed antifungal activity.


2008 ◽  
Vol 1 (1) ◽  
pp. 164-171 ◽  
Author(s):  
Koffi Koba ◽  
P W Poutouli ◽  
Christine Raynaud ◽  
Komla Sanda

The aerial parts of Ocimum gratissimum L. (Lamiaceae) harvested in Togo was steam-distilled and investigated for essential oil composition (GC and GC/MS) and in vitro antifungal activities. Thymol (31.79 %), p-cymene (15.57 %) and γ-terpinene (12.34 %) and were the major components of the oil. Other notable components identified in this oil were myrcene (6.94 %) and α-thujene (6.11 %).The in vitro antifungal activity was recorded with the minimum inhibitory concentrations (MICs) ranging from 80 to 150 µl.l-1, 150 to 500 µl.l-1  and from 100 to 150 µl.l-1 respectively on dermatophytes, imperfect filamentous fungi and pathogenic yeasts. Likewise, on tested fungi the minimum fungicidal concentration (MFC) varied from 300 µl.l-1 to 500 µl.l-1, 500 to 700 µl.l-1 and from 250 to 300 µl.l-1, respectively on dermatophytes, imperfect filamentous fungi and pathogenic yeasts. Keywords: O.gratissimum,  Antifungal, Essential oil; Thymol. © 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v1i1.1131 


2014 ◽  
Vol 29 (12) ◽  
pp. 1173-1176 ◽  
Author(s):  
Anahi Bucchini ◽  
Donata Ricci ◽  
Federica Messina ◽  
Maria Carla Marcotullio ◽  
Massimo Curini ◽  
...  

2017 ◽  
Vol 19 (2) ◽  
pp. 1-10 ◽  
Author(s):  
Edwin Enciso-Roca ◽  
Enrique Aguilar-Felices ◽  
Johnny Tinco-Jayo ◽  
Jorge Arroyo-Acevedo ◽  
Oscar Herrera-Calderon ◽  
...  

Processes ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 1003
Author(s):  
Wael A.A. Abo Elgat ◽  
Ahmed M. Kordy ◽  
Martin Böhm ◽  
Robert Černý ◽  
Ahmed Abdel-Megeed ◽  
...  

Several molds are able to colonize wood and many building products or solid wood causing losses for their valuable uses. Essential oils (EOs) from aromatic plants can be used as an ecofriendly biofungicide against the growth of several molds. EOs from Eucalyptus camaldulensis, Citrus aurantium, and C. sinensis have a broad-spectrum antimicrobial activity. EOs from of E. camaldulensis air-dried aerial parts, C. aurantium leaf and C. sinensis peel, and their combinations (1:1 v/v) were evaluated for their antifungal activity against the growth of four common mold fungi (Aspergillus flavus, A. niger, A. terreus, and Fusarium culmorum). The chemical compositions of the EOs were analyzed with GC/MS. The main compounds in EO from E. camaldulensis were spathulenol (20.84%), eucalyptol (12.01%), and sabinene (9.73%); in C. aurantium were linalyl acetate (42.29%), and linalool (29.76%); and in C. sinensis were D-limonene (73.4%) and γ-terpinene (22.6%). At 50 µL/mL, C. sinensis EO showed the highest fungal mycilial growth inhibition (FMGI) percentage (86.66%) against A. flavus. C. sinensis, E. camaldulensis, and E. camaldulensis/C. sinensis showed FMGI values of 96%, 91.66%, and 75.66% respectively, against A. niger. EOs from C. aurantium and C. sinensis showed potent activity against A. terreus (100% FMGI), while C. aurantium/E. camaldulensis and E. camaldulensis/C. sinensis showed FMGI values of 74.33% and 70.66%, respectively. Potent activity against F. culmorum with 100% was observed as the application of E. camaldulensis and C. sinensis EOs at 50 µL/mL, while E. camaldulensis/C. sinensis (50 µL/mL) showed FMGI value of 65.66%. The results suggest using the EOs and their combinations from E.camaldulensis, C. aurantium, and C. sinensis as a biofungicide against molds. The potent properties of EOs offer the possibility of using them as eco-friendly, safe, and cost-effective antimicrobials for molds that could cause discoloration of the wood packaging or food spoilage.


2016 ◽  
Vol 11 (12) ◽  
pp. 1934578X1601101 ◽  
Author(s):  
Joyce Kelly R. da Silva ◽  
Nayla N. S. Silva ◽  
Jessica Fernanda S. Santana ◽  
Eloísa Helena A. Andrade ◽  
José Guilherme S. Maia ◽  
...  

The essential oils (EOs) from aerial parts of Piper aduncum, P. callosum and P. marginatum, collected from the Amazon region of Brazil, were analyzed by GC-MS and then evaluated for their antifungal and anticholinesterase activities. The essential oils were dominated by phenylpropanoids, such as dillapiole (73.0%) in P. aduncum, safrole (66.0%) in P. callosum and 3,4-methylenedioxypropiophenone (21.8%) in P. marginatum. The analyzed oils showed low to moderate antifungal activity, with detection limits (DL) from 10 to 100 μg against Cladosporium cladosporioides and C. sphareospermum. In the anticholinesterase (AChE) evaluation, the oils of P. callosum (DL = 0.01 ng) and P. marginatum (DL = 0.01 ng) were one hundred times more potent than the standard physostigmine (DL = 1.0 ng). Molecular docking analysis showed that phenylpropanoids docked reasonably well with acetylcholinesterase and may be responsible for the anti-AChE activities of the Piper EOs. This is the first presentation about acetylcholinesterase inhibition by methylenedioxyphenyl-propanoids.


Sign in / Sign up

Export Citation Format

Share Document