scholarly journals Langmuir-Blodgett monolayers holding a wound healing active compound and its effect in cell culture. A model for the study of surface mediated drug delivery systems

Heliyon ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e06436
Author(s):  
Luciana Fernández ◽  
Ana Lucía Reviglio ◽  
Daniel A. Heredia ◽  
Gustavo M. Morales ◽  
Marisa Santo ◽  
...  
2021 ◽  
Vol 18 ◽  
Author(s):  
Hitesh Chopra ◽  
Inderbir Singh ◽  
Sandeep Kumar ◽  
Tanima Bhattacharya ◽  
Md. Habibur Rahman ◽  
...  

: The conventional drug delivery systems have a long list of issues of repeated dosing and toxicity arising due to it. The hydrogels are the answer to them and offer a result that minimizes such activities and optimizes therapeutic benefits. The hydrogels proffer tunable properties that can withstand degradation, metabolism, and controlled release moieties. Some of the areas of applications of hydrogels involve wound healing, ocular systems, vaginal gels, scaffolds for tissue, bone engineering, etc. They consist of about 90% of the water that makes them suitable bio-mimic moiety. Here, we present a birds-eye view of various perspectives of hydrogels, along with their applications.


2021 ◽  
Vol 14 (10) ◽  
pp. 946
Author(s):  
Bianca Enaru ◽  
Sonia Socaci ◽  
Anca Farcas ◽  
Carmen Socaciu ◽  
Corina Danciu ◽  
...  

Liposome-based delivery systems have been studied and used more frequently in recent years due to their advantages, such as low toxicity, specificity, and the ability to protect the encapsulated substance from environmental factors, which could otherwise degrade the active compound and reduce its effectiveness. Given these benefits, many researchers have encapsulated polyphenols in liposomes, thus increasing their bioavailability and stability. Similarly, polyphenols encapsulated in liposomes are known to produce more substantial effects on targeted cells than unencapsulated polyphenols, while having minimal cytotoxicity in healthy cells. Although polyphenols play a role in preventing many types of disease and generally have beneficial effects on health, we solely focused on their chemopreventive effects on cancer through liposomes in this review. Our goal was to summarize the applicability and efficacy of liposomes encapsulated with different classes of polyphenols on several types of cancer, thus opening the opportunity for future studies based on these drug delivery systems.


2021 ◽  
Vol 28 ◽  
Author(s):  
Jing Li ◽  
Qinhua Chen ◽  
Jin Wang ◽  
Xiaoyan Pan ◽  
Jie Zhang

: Hydrogel is a hydrophilic but water-soluble polymer system with a three-dimensional network structure. Hydrogel can absorb large amounts of water and maintain its shape and remain soft. The high-moisturizing properties, good biocompatibility and controlled biodegradability of hydrogels have allowed them to be widely used in wound dressing, tissue engineering, controlled drug delivery systems and other fields. This article reviews the most widely used antibacterial gel dressings for wound healing in recent years and focuses on the application of an environmentally responsive intelligent hydrogel delivery system. Finally, the development prospects and challenges of hydrogel wound dressings are forecasted.


2008 ◽  
Vol 97 (8) ◽  
pp. 2892-2923 ◽  
Author(s):  
Joshua S. Boateng ◽  
Kerr H. Matthews ◽  
Howard N.E. Stevens ◽  
Gillian M. Eccleston

2018 ◽  
Vol Volume 13 ◽  
pp. 5023-5043 ◽  
Author(s):  
Marziyeh Hajialyani ◽  
Devesh Tewari ◽  
Eduardo Sobarzo-Sánchez ◽  
Seyed Mohammad Nabavi ◽  
Mohammad Hosein Farzaei ◽  
...  

2018 ◽  
Vol 127 ◽  
pp. 138-166 ◽  
Author(s):  
Saghi Saghazadeh ◽  
Chiara Rinoldi ◽  
Maik Schot ◽  
Sara Saheb Kashaf ◽  
Fatemeh Sharifi ◽  
...  

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