scholarly journals B-PO03-033 CARDIAC REPARATIVE THERAPY WITH ADIPOSE GRAFT TRANSPOSITION PROCEDURE IMPROVES ELECTROPHYSIOLOGICAL REMODELING OF CHRONIC MYOCARDIAL INFARCTION

Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S202
Author(s):  
Raquel Adelino ◽  
Carolina Galvez-Monton Daina Martinez-Falguera ◽  
Carolina Curiel Albert Teis ◽  
Roger Marsal Oriol Rodriguez-Leor ◽  
Axel Sarrias Víctor Bazan ◽  
...  
Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S105-S106
Author(s):  
Kanchan Kulkarni ◽  
Nestor Pallares-Lupon ◽  
Virginie Loyer ◽  
Stephane Bloquet ◽  
Dounia El Hamrani ◽  
...  

2014 ◽  
Vol 24 (6) ◽  
pp. 1211-1218 ◽  
Author(s):  
Julian L. Wichmann ◽  
Ruta Arbaciauskaite ◽  
J. Matthias Kerl ◽  
Claudia Frellesen ◽  
Boris Bodelle ◽  
...  

1992 ◽  
Vol 72 (4) ◽  
pp. 1437-1443 ◽  
Author(s):  
T. I. Musch

The hemodynamic response to maximal exercise was determined in rats with a chronic myocardial infarction (MI) that were subjected to 6–8 wk of high-intensity sprint training (HIST) or limited exercise activity (sedentary control). Training was performed 6 days/wk and consisted of five 1-min bouts of treadmill running at work loads (15% grade, 97 m/min) in excess of the animal's maximal O2 uptake (VO2max). The left ventricular infarct size for the HIST and sedentary control rats was 35 +/- 4 and 34 +/- 3% of the total endocardial circumference, respectively. VO2max was significantly greater for MI rats subjected to the HIST paradigm than for sedentary control rats. This increase in VO2max was due to an increase in the maximal stroke volume that could be generated by the HIST rat during exercise, inasmuch as the maximal heart rate response and the ability to extract O2 from the blood were similar between the two groups of rats. Citrate synthase activities measured in the plantaris muscle of the HIST and sedentary control rats were similar. These results suggest that the increase in VO2max produced with HIST in MI rats may be linked to changes in central cardiac function, as indicated by the increase in maximal stroke volume that could be generated by the MI rat during maximal exercise conditions.


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