First report of the plasmid-mediated colistin resistance gene mcr-1 in a clinical Escherichia coli isolate in Algeria

2016 ◽  
Vol 48 (6) ◽  
pp. 760-761 ◽  
Author(s):  
Betitera Yanat ◽  
Jesús Machuca ◽  
Radia Dali Yahia ◽  
Abdelaziz Touati ◽  
Álvaro Pascual ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Colistin Resistance ◽  
Coli Isolate ◽  
First Report

First report of Escherichia coli carrying the mobile colistin resistance gene mcr-1 in Turkey

2018 ◽  
Vol 15 ◽  
pp. 169-170 ◽  
Author(s):  
Cemil Kurekci ◽  
Muhsin Aydin ◽  
Ozkan Ufuk Nalbantoglu ◽  
Aycan Gundogdu
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Colistin Resistance ◽  
First Report

scholarly journals First report of the mcr-1 colistin resistance gene identified in two Escherichia coli isolates from clinical samples, Philippines, 2018

2020 ◽  
Vol 21 ◽  
pp. 291-293
Author(s):  
John Mark S. Velasco ◽  
Ma. Theresa G. Valderama ◽  
Katie R. Margulieux ◽  
Paula Corazon S. Diones ◽  
Angeli Mae B. Reyes ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Clinical Samples ◽  
Colistin Resistance ◽  
First Report

scholarly journals Autochthonous case of mobile colistin resistance gene mcr-1 from a uropathogenic Escherichia coli isolate in Sétif Hospital, Algeria

2019 ◽  
Vol 19 ◽  
pp. 356-357 ◽  
Author(s):  
Larbi Zakaria Nabti ◽  
Farida Sahli ◽  
Linda Hadjadj ◽  
Edgarthe Priscilla Ngaiganam ◽  
David Lupande-Mwenebitu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Uropathogenic Escherichia Coli ◽  
Colistin Resistance ◽  
Coli Isolate ◽  
Autochthonous Case

scholarly journals Full Genome Sequence of pT3, a Multiresistant Plasmid Carrying the mcr-3.5 Colistin Resistance Gene, Recovered from an Extended-Spectrum-β-Lactamase-Producing Escherichia coli Isolate from Crickets Sold as Food

2019 ◽  
Vol 8 (29) ◽  
Author(s):  
Katrin Zurfluh ◽  
Marc J. A. Stevens ◽  
Melissa Bucher ◽  
Laurent Poirel ◽  
Patrice Nordmann ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multidrug Resistance ◽  
Resistance Gene ◽  
Genome Sequence ◽  
Resistance Genes ◽  
Full Genome Sequence ◽  
Full Genome ◽  
Colistin Resistance ◽  
Coli Isolate ◽  
Single Plasmid

Here, we sequenced multidrug resistance plasmid pT3, which encodes mcr-3.5 and other resistance genes. The cooccurrence of mcr genes and other resistance genes on a single plasmid is of concern.

scholarly journals ISKpn40-Mediated Mobilization of the Colistin Resistance Gene mcr-3.11 in Escherichia coli

2020 ◽  
Vol 64 (10) ◽  
Author(s):  
Yu-Zhang He ◽  
Teng-Fei Long ◽  
Cai-Ping Chen ◽  
Bing He ◽  
Xing-Ping Li ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Wild Type ◽  
Colistin Resistance ◽  
Content Type ◽  
First Report ◽  
E Coli ◽  
Target Sites

ABSTRACT The mobile colistin resistance gene mcr-3 has globally disseminated since it was first reported in 2017 in Escherichia coli. In vitro mobilization assays in this study demonstrate the functionality of the composite transposon structure ISKpn40-mcr-3.11-dgkA-ISKpn40 in wild-type and recA− E. coli strains. These transpositions generated 4-bp duplications at the target sites. This is the first report demonstrating the mobility of the mcr-3.11 gene by transposition.

scholarly journals Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient

2017 ◽  
Vol 61 (4) ◽  
Author(s):  
Rainer Hartl ◽  
Heidrun Kerschner ◽  
Sarah Lepuschitz ◽  
Werner Ruppitsch ◽  
Franz Allerberger ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Resistance Gene ◽  
Stool Sample ◽  
Genetic Background ◽  
Clonal Diversity ◽  
Multidrug Resistant ◽  
Colistin Resistance ◽  
Oncology Patient ◽  
Content Type ◽  
Coli Isolate

ABSTRACT Since colistin resistance based on the plasmid-encoded mcr-1 gene was first described, this resistance gene in Enterobacteriaceae has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation of mcr-1 in a human Escherichia coli strain cultured from a surveillance stool sample of an Austrian oncology patient.

scholarly journals Emergence of Plasmid-Mediated Colistin Resistance Genemcr-1in a Clinical Escherichia coli Isolate from Egypt

2016 ◽  
Vol 60 (5) ◽  
pp. 3249-3250 ◽  
Author(s):  
Shimaa S. Elnahriry ◽  
Hazim O. Khalifa ◽  
Ahmed M. Soliman ◽  
Ashraf M. Ahmed ◽  
Alaaddin M. Hussein ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Colistin Resistance ◽  
Coli Isolate

scholarly journals First Report and Comparative Genomics Analysis of a blaOXA-244–Harbouring Escherichia coli Isolate Recovered in American Continent

2019 ◽  
Author(s):  
Deisy J Abril ◽  
Ingrid Gisell Bustos Moya ◽  
Ricaurte Alejandro Marquez-Ortiz ◽  
Diego Fernando Josa Montero ◽  
Zayda Lorena Corredor Rozo ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Comparative Genomics ◽  
Genomic Island ◽  
Genomic Analysis ◽  
American Continent ◽  
Incompatibility Group ◽  
Coli Isolate ◽  
First Report ◽  
E Coli ◽  
Comparative Genomics Analysis

The carbapenemase OXA-244 is a derivate of OXA-48, and its detection is very difficult in laboratories. Here we report the identification and genomic analysis of an Escherichia coli isolate (28Eco12) harbouring the blaOXA-244 gene identified in Colombia, South America. The 28Eco12 isolate was identified during a retrospective study and it was recovered from a patient treated in Colombia. The complete nucleotide sequence was established using the PacBio platform. A comparative genomics analysis with other blaOXA-244–harbouring Escherichia coli strains was performed. The 28Eco12 isolate belonged to sequence type (ST) 38 and its genome was composed of two molecules, a chromosome of 5,343,367 bp and a plasmid of 92,027 bp, which belonged to the incompatibility group IncY and did not harbour resistance genes. The blaOXA-244 gene was chromosomally-encoded and mobilized by an ISR1-related Tn6237 composite transposon. Notably, this transposon was inserted and located within a new genomic island. For our knowledge this is the first report of a blaOXA-244–harbouring Escherichia coli isolate in American continent.Our results suggest that the introduction of the OXA-244-producing E. coli isolate was through clonal expansion of the ST38 pandemic clone. Other isolates producing OXA-244 could be circulating silently on the American continent.

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