Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel

2011 ◽  
Vol 48 (1) ◽  
pp. 38-43 ◽  
Author(s):  
Swagata Das ◽  
Biswajit Mishra ◽  
Kamaldeep Gill ◽  
Md. Saquib Ashraf ◽  
Abhay Kumar Singh ◽  
...  
Author(s):  
Iqra Sarfraz ◽  
Azhar Rasul ◽  
Ghulam Hussain ◽  
Muhammad Ajmal Shah ◽  
Bushra Nageen ◽  
...  

: Oxalis corniculata (Oxalidaceae) is a small decumbent and delicate appearing medicinal herb flourishing in warm temperate and tropical domains such as Pakistan and India. Main bioactive chemical constituents of Oxalis plant include several alkaloids, flavonoids, terpenoids, cardiac glycosides, saponins, phlobatannins along with steroids. Due to its polyphenolic, glycosides and flavonoid profile, it is proved to be protective in numerous ailments and exhibit various biological activities such as anti-fungal, anti-cancer, anti-oxidant, anti-bacterial, anti-diabetic, and cardioprotective. Moreover, bioactive phytochemicals from this plant possess significant wound healing potential. Our current effort intends to emphasize on the immense significance of this plant species, which have not been the subject matter of clinical trials and effective pharmacological studies, even though its favored usage has been stated. This review proposes that Oxalis corniculata possess potential for the cure of various diseases, however, further researches on isolation and characterization of bioactive compounds along with pre-clinical trials are compulsory to figure out its pharmacological applications.


INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (09) ◽  
pp. 52-53
Author(s):  
M.B Mulik ◽  
◽  
K.S. Laddha

Aristolochic Acids (AAs) are major components of plants in Aristolochia species. The plant Aristolochia indica Linn. has diverse biological actions such as analgesic, anti-diabetics, anti-bacterial, anti-fungal and treatment of malaria and fevers. Here, we report a new and simple isolation method of Aristolochic Acid-Ι (AA-I) from leaves of Aristolochia indica Linn. Defatted leaves of A. indica were extracted with chloroform by soxhlation. AA-I was further isolated from the chloroform extract by partitioning with aqueous sodium bicarbonate. AA-I was purified by repetitive washings with methanol and recrystallization in methanol yielded yellow leaflets. The purity of the isolated compound was ascertained by HPLC analysis. structural elucidation of the isolated compound was done by IR, MS and NMR spectral analysis.


2019 ◽  
Vol 33 (4) ◽  
pp. 303-324 ◽  
Author(s):  
Rutairat Suttisuwan ◽  
Saranya Phunpruch ◽  
Tanatorn Saisavoey ◽  
Papassara Sangtanoo ◽  
Nuttha Thongchul ◽  
...  

2000 ◽  
Vol 275 (2) ◽  
pp. 589-594 ◽  
Author(s):  
Hiroshi Nagai ◽  
Kyoko Takuwa ◽  
Masahiro Nakao ◽  
Bryan Sakamoto ◽  
Gerald L Crow ◽  
...  

Author(s):  
Phatangare N. D. ◽  
Deshmukh K. K. ◽  
Murade V. D. ◽  
Hase G. J. ◽  
Gaje T.R.

Justicia gendarussa burm.f. has become important source of Phytol which is associated with other phenolic,terpenoids,alkaloids. Diterpenes shows anti-inflammatory activity. Phytol is a acyclic diterpene alcohol found as essential oil in aromatic plants.oil is obtained by Keshav-Naren apparatus (patent no:2343/Mum/2013/A).Phytol separated from other oil part by fractional distillation. It separated at 204-2080C.Characterization of Phytol carried out by IR,NMR,and mass spectrometry. Phytol shows potent as Anti-inflammatory activity by releasing histamine (26.92%), serotin and bradykinin (49.90%), and prostaglandin (68.03%) as compared to standard (Dicolfenac 5mg/kg).


2021 ◽  
Vol 37 (2) ◽  
pp. 413-418
Author(s):  
Sachin Govind Bibave ◽  
S. J. Takate ◽  
A.E. Athare

Theβ-dike toneis synthesizedvia the named Baker-Venkataraman. In currenttask, β-dike tone ligand mixed with different metal nitrates and form different metal complexes such as Ni(II), Fe(III), Cr(III). Ligand gives tautomerism, this tautomerism process was examined with the help ofFTIR.Because of enol assist as ligand in the metal complexes preparation. The preparedmetal complexearede scribed by various techniques like elemental analysis, FTIR, DTA, TGA, magnetic properties and molar conductivities. Different properties of complexes are studied such as antioxidant, antibacterial, anti-inflammatory and anti fungal properties.


Marine Drugs ◽  
2020 ◽  
Vol 18 (12) ◽  
pp. 597
Author(s):  
Xiaojie Lu ◽  
Junjie He ◽  
Yanhua Wu ◽  
Na Du ◽  
Xiaofan Li ◽  
...  

In the present study, four new compounds including a pair of 2-benzoyl tetrahydrofuran enantiomers, namely, (−)-1S-myrothecol (1a) and (+)-1R-myrothecol (1b), a methoxy-myrothecol racemate (2), and an azaphilone derivative, myrothin (3), were isolated along with four known compounds (4–7) from cultures of the deep-sea fungus Myrothecium sp. BZO-L062. Enantiomeric compounds 1a and 1b were separated through normal-phase chiral high-performance liquid chromatography. The absolute configurations of 1a, 1b, and 3 were assigned by ECD spectra. Among them, the new compound 1a and its enantiomer 1b exhibited anti-inflammatory activity, inhibited nitric oxide formation in lipopolysaccharide-treated RAW264.7 cells, and exhibited antioxidant activity in the 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and oxygen radical absorbance capacity assays.


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