Resistant starch produces antidiabetic effects by enhancing glucose metabolism and ameliorating pancreatic dysfunction in type 2 diabetic rats

2018 ◽  
Vol 110 ◽  
pp. 276-284 ◽  
Author(s):  
Hui Sun ◽  
Xiaohan Ma ◽  
Shiqi Zhang ◽  
Dan Zhao ◽  
Xiong Liu
Keyword(s):  
Glucose Metabolism ◽  
Resistant Starch ◽  
Diabetic Rats ◽  
Pancreatic Dysfunction ◽  
Type 2 Diabetic ◽  
Antidiabetic Effects

Synergistic effect of quercetin and 6-gingerol treatment in streptozotocin induced type 2 diabetic rats and poloxamer P-407 induced hyperlipidemia

RSC Advances ◽  
2016 ◽  
Vol 6 (15) ◽  
pp. 12235-12242 ◽  
Author(s):  
Yi Shao ◽  
Yao Yu ◽  
Cheng Li ◽  
Jing Yu ◽  
Rongrong Zong ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Diabetic Rats ◽  
Type 2 Diabetic ◽  
Antidiabetic Effects

Ginger and quercetin have been reported to have significant antidiabetic effects.

Effect of guava (Psidium guajavaLinn.) leaf soluble solids on glucose metabolism in type 2 diabetic rats

2008 ◽  
Vol 22 (11) ◽  
pp. 1458-1464 ◽  
Author(s):  
Szu-Chuan Shen ◽  
Fang-Chi Cheng ◽  
Ning-Jung Wu
Keyword(s):  
Glucose Metabolism ◽  
Diabetic Rats ◽  
Soluble Solids ◽  
Type 2 Diabetic

scholarly journals AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats

2012 ◽  
Vol 33 (1) ◽  
pp. 82-90 ◽  
Author(s):  
Hans Ludwig Schäfer ◽  
Wolfgang Linz ◽  
Eugen Falk ◽  
Maike Glien ◽  
Heiner Glombik ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Lipid Profile ◽  
Diabetic Rats ◽  
Type 2 Diabetic ◽  
Pparα Agonist

Molecular Mechanism Underlying the Antidiabetic Effects of a Siddha Polyherbal Preparation in the Liver of Type 2 Diabetic Adult Male Rats

2012 ◽  
Vol 18 (1) ◽  
pp. 29-42 ◽  
Author(s):  
Venkataraman Balaji ◽  
Jayaraman Selvaraj ◽  
Sampath Sathish ◽  
Chinnaiyan Mayilvanan ◽  
Karundevi Balasubramanian
Keyword(s):  
Insulin Receptor ◽  
Molecular Mechanism ◽  
Diabetic Rats ◽  
Male Rats ◽  
Tinospora Cordifolia ◽  
Syzygium Aromaticum ◽  
Mrna Levels ◽  
Type 2 Diabetic ◽  
Antidiabetic Effects

A siddha polyherbal preparation consisting of 5 medicinal plants, namely, Asparagus racemosus, Emblica officinalis, Salacia oblonga, Syzygium aromaticum, and Tinospora cordifolia, in equal ratio, was formulated to examine the molecular mechanism by which it exhibits antidiabetic effects in the liver of high-fat and fructose-induced type 2 diabetic rats. The polyherbal preparation treated type 2 diabetic rats showed an increase in insulin receptor, Akt, and glucose transporter2 mRNA levels compared with diabetic rats. Insulin receptor, insulin receptor substrate-2, Akt, phosphorylated Akt substrate of 160kDaThreonine642, α-Actinin-4, β-arrestin-2, and glucose transporter2 proteins were also markedly decreased in diabetic rats, whereas the polyherbal preparation treatment significantly improved the expression of these proteins more than that of metformin-treated diabetic rats. The expression pattern of insulin signaling molecules analyzed in the present study signifies the therapeutic efficacy of the siddha polyherbal preparation.

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