Preparation of pH-sensitive Fe3O4@C/carboxymethyl cellulose/chitosan composite beads for diclofenac sodium delivery

2019 ◽  
Vol 127 ◽  
pp. 594-605 ◽  
Author(s):  
Xiaoxiao Sun ◽  
Jiafeng Shen ◽  
Di Yu ◽  
Xiao-kun Ouyang
2021 ◽  
pp. 118084
Author(s):  
Ahmed M. Omer ◽  
Eman M. Abd El-Monaem ◽  
Mona M. Abd El-Latif ◽  
Gehan M. El-Subruiti ◽  
Abdelazeem S. Eltaweil

2014 ◽  
Vol 71 (11) ◽  
pp. 2923-2944 ◽  
Author(s):  
Huiqiong Yan ◽  
Xiuqiong Chen ◽  
Tiantian Wu ◽  
Yuhong Feng ◽  
Chunxiu Wang ◽  
...  

2017 ◽  
Vol 96 ◽  
pp. 459-465 ◽  
Author(s):  
Seda Çınar ◽  
Ümit H. Kaynar ◽  
Tülin Aydemir ◽  
Sermin Çam Kaynar ◽  
Mehmet Ayvacıklı

2018 ◽  
Vol 7 (4) ◽  
pp. 291-301 ◽  
Author(s):  
Zepeng Jiao ◽  
Bin Zhang ◽  
Chunya Li ◽  
Weicong Kuang ◽  
Jingxian Zhang ◽  
...  

Abstract A drug delivery system based on carboxymethyl cellulose-grafted graphene oxide loaded by methotrexate (MTX/CMC-GO) with pH-sensitive and controlled drug-release properties was developed in this work. CMC was grafted on graphene oxide by ethylenediamine through hydrothermal treatment. CMC serves as a pH-sensitive trigger, while CMC-GO serves as a drug-carrying vehicle due to the curved layer and large plain surface. Different amounts of drugs could be loaded into CMC-GO nanocarriers by control of the original amount of drug/carrier ratios. Additionally, low cytotoxicity against NIH-3T3 cells and low in vivo toxicity was observed. In vivo tumor growth inhibition assays showed that MTX/CMC-GO demonstrated superior antitumor activity than free MTX against HT-29 cells. Moreover, prolonged survival time of mice was observed after MTX/CMC-GO administration. The MTX/CMC-GO drug delivery system has a great potential in colon cancer therapy.


2013 ◽  
Vol 52 (8) ◽  
pp. 795-805 ◽  
Author(s):  
Shiv Sankar Bhattacharya ◽  
Seema Shukla ◽  
Subham Banerjee ◽  
Purojit Chowdhury ◽  
Prithviraj Chakraborty ◽  
...  

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