scholarly journals Difference in risk factors of silent brain infarction between paroxysmal and persistent atrial fibrillation

2021 ◽  
Vol 33 ◽  
pp. 100753
Author(s):  
Andrew T Kim ◽  
Shinichi Iwata ◽  
Sera Ishikawa ◽  
Soichiro Tamura ◽  
Masanori Matsuo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Brain Infarction ◽  
Persistent Atrial Fibrillation ◽  
Silent Brain Infarction

scholarly journals The analysis of the connection between plaque morphology of the asymptomatic carotid stenosis and ischemic brain lesions

2013 ◽  
Vol 70 (11) ◽  
pp. 993-998 ◽  
Author(s):  
Djordje Milosevic ◽  
Janko Pasternak ◽  
Vladan Popovic ◽  
Dragan Nikolic ◽  
Pavle Milosevic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Carotid Stenosis ◽  
Carotid Plaque ◽  
Brain Infarction ◽  
Statistical Significance ◽  
Brain Parenchyma ◽  
Plaque Morphology ◽  
Asymptomatic Carotid Stenosis ◽  
Asymptomatic Carotid ◽  
Silent Brain Infarction

Background/Aim. A certain percentage of patients with asymptomatic carotid stenosis have an unstable carotid plaque. For these patients it is possible to register by modern imaging methods the existence of lesions of the brain parenchyma - the silent brain infarction. These patients have a greater risk of ischemic stroke. The aim of this study was to analyze the connection between the morphology of atherosclerotic carotid plaque in patients with asymptomatic carotid stenosis and the manifestation of silent brain infarction, and to analyze the influence of risk factors for cardiovascular diseases on the occurrence of silent brain infarction and the morphology of carotid plaque. Methods. This retrospective study included patients who had been operated for high grade (> 70%) extracranial atherosclerotic carotid stenosis at the Clinic for Vascular and Transplantation Surgery of the Clinical Center of Vojvodina over a period of 5 years. The patients analyzed had no clinical manifestation of cerebrovascular insufficiency of the carotid artery territory up to the time of operation. The classification of carotid plaque morphology was carried out according to the Gray-Weale classification, after which all the types were subcategorized into two groups: stable and unstable. Brain lesions were verified using preoperative imaging of the brain parenchyma by magnetic resonance. We analyzed ipsilateral lesions of the size > or = 3 mm. Results. Out of a 201 patients 78% had stable plaque and 22% unstable one. Unstable plaque was prevalent in the male patients (male/female ratio = 24.8% : 17.8%), but without a statistically significant difference (p > 0.05). The risk factors (hypertension, nicotinism, hyperlipoproteinemia, and diabetes mellitus) showed no statistically significant impact on carotid plaque morphology and the occurrence of silent brain infarction. Silent brain infarction was detected in 30.8% of the patients. Unstable carotid plaque was found in a larger percentage of patients with silent brain infarction (36.4% : 29.3%) but without a significant statistical difference (p > 0.05). Conclusions. Even though silent brain infarction is more frequent in patients with unstable plaque of carotid bifurication, the difference is of no statistical significance. The effects of the number and type of risk factors bear no statistical significance on the incidence of morphological asymptomatic carotid plaque.

scholarly journals Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis

2020 ◽  
Vol 10 (3) ◽  
pp. 116-123
Author(s):  
Ayaka Ito ◽  
Shinichi Iwata ◽  
Soichiro Tamura ◽  
Andrew T. Kim ◽  
Shinichi Nonin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Aortic Stenosis ◽  
Brain Infarction ◽  
Multiple Logistic Regression Analysis ◽  
Brain Magnetic Resonance Imaging ◽  
Multidetector Row Computed Tomography ◽  
Increased Risk ◽  
Lower Egfr ◽  
Silent Brain Infarction ◽  
Ischemic Attack

<b><i>Introduction:</i></b> Silent brain infarction (SBI) is an independent risk factor for subsequent symptomatic stroke in the general population. Although aortic stenosis (AS) is also known to be associated with an increased risk of future symptomatic stroke, little is known regarding the prevalence and risk factors for SBI in patients with AS. <b><i>Methods:</i></b> The study population comprised 83 patients with severe AS with no history of stroke or transient ischemic attack and paralysis or sensory impairment (mean age 75 ± 7 years). All patients underwent brain magnetic resonance imaging to screen for SBI and multidetector-row computed tomography to quantify the aortic valve calcification (AVC) volume. Comprehensive transthoracic and transesophageal echocardiography were performed to evaluate left atrial (LA) abnormalities, such as LA enlargement, spontaneous echo contrast, or abnormal LA appendage emptying velocity (&#x3c;20 cm/s), and complex plaques in the aortic arch. <b><i>Results:</i></b> SBI was detected in 38 patients (46%). Multiple logistic regression analysis indicated that CHA<sub>2</sub>DS<sub>2</sub>-VASc score and estimated glomerular filtration rate (eGFR) were independently associated with SBI (<i>p</i> &#x3c; 0.05), whereas LA abnormalities and AVC volume were not. When patients were divided into 4 groups according to CHA<sub>2</sub>DS<sub>2</sub>-VASc score and eGFR, the group with a higher CHA<sub>2</sub>DS<sub>2</sub>-VASc score (≥4) and a lower eGFR (&#x3c;60 mL/min/1.73 m<sup>2</sup>) had a greater risk of SBI than the other groups (<i>p</i> &#x3c; 0.05). <b><i>Conclusion:</i></b> These findings indicate that AS is associated with a high prevalence of SBI, and that the CHA<sub>2</sub>DS<sub>2</sub>-VASc score and eGFR are useful for risk stratification.

MODERN UNDERSTANDING OF RISK FACTORS AND PREVENTION OF BRAIN INFARCTION(LITERATURE REVIEW)

2020 ◽  
Vol 3 (1) ◽  
pp. 16-20
Author(s):  
Malika Kamalova ◽  
◽  
Nodir Khaydarov ◽  
Shavka Islamov ◽  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Ischemic Stroke ◽  
Brain Infarction ◽  
Qualitative Approach ◽  
Blood Cholesterol ◽  
High Blood Cholesterol ◽  
The World ◽  
Rehabilitation Period

Stroke is the leading cause of death and disability in the world. Statistics from Uzbekistan show that over 60,000 new strokes occur each year. At the same time, more than 160 new cases occur daily in the country. In Tashkent alone, 25-30 cases of stroke occur every day. In Tashkent alone, 25-30 strokes areobserved daily [1,7]. The main risk factors for atherothromboembolic ischemic stroke are, high blood pressure, high blood cholesterol, smoking and diabetes; and the main risk factors for cardiogenic ischemic stroke are atrial fibrillation and coronary heartdisease. Strategies to reduce the frequency of strokes include the prevention of primary and secondary (repeated) stroke, as well as the rehabilitation period of patients. With a qualitative approach, the mortality and disability of patients is reduced

PREVENTION AND RISK FACTORS FOR BRAIN INFARCTION(LITERATURE REVIEW)

2020 ◽  
Vol 2 (1) ◽  
pp. 14-16
Author(s):  
Malika Kamalova ◽  
◽  
Nodir Khaidarov ◽  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Literature Review ◽  
Brain Infarction ◽  
Blood Cholesterol ◽  
High Blood Cholesterol

Stroke is the leading cause of death and disability in the world.Statistics from Uzbekistan show that over 60,000 new strokes occur each year. At the same time, more than 160 new cases occur daily in the country. In Tashkent alone, 25-30 cases of stroke occur every day. In Tashkent alone, 25-30 strokes are observed daily [1].The main risk factors for atherothromboembolic ischemic stroke are, high blood pressure, high blood cholesterol, smoking and diabetes; and the main risk factors for cardiogenic ischemic stroke are atrial fibrillation and coronary heart disease.

Abstract TP415: Coated-Platelet Levels Are Elevated Among Native American Veterans With Vascular Risk Factors and Silent Brain Infarction

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Angelia Kirkpatrick ◽  
Julie A Stoner ◽  
Eleanor Mathews ◽  
George L Dale ◽  
Calin I Prodan
Keyword(s):  
Risk Factors ◽  
Native American ◽  
Brain Infarction ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Silent Brain Infarction
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