Occurrence, antimicrobial resistance and whole genome sequence analysis of Salmonella Serovars from pig farms in Ilorin, north-Central Nigeria

2021 ◽  
pp. 109245
Author(s):  
I.A. Raufu ◽  
O.A. Ahmed ◽  
A. Aremu ◽  
J.A. Ameh ◽  
R.E. Timme ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Antimicrobial Resistance ◽  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
North Central ◽  
Genome Sequence Analysis ◽  
Pig Farms ◽  
Salmonella Serovars

scholarly journals Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance

2021 ◽  
Vol 7 (5) ◽  
Author(s):  
George E. Stenhouse ◽  
Khuzwayo C. Jere ◽  
Chikondi Peno ◽  
Rebecca J. Bengtsson ◽  
End Chinyama ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Antimicrobial Resistance ◽  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Fluoroquinolone Resistance ◽  
Whole Genome ◽  
Genome Sequence Analysis ◽  
Content Type ◽  
Link Type ◽  
Global Priority

Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

scholarly journals Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance

2020 ◽  
Author(s):  
George E. Stenhouse ◽  
Khuzwayo C. Jere ◽  
Chikondi Peno ◽  
Rebecca J. Bengtsson ◽  
End Chinyama ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Antimicrobial Resistance ◽  
Genome Sequence ◽  
Resistance Determinant ◽  
Whole Genome Sequence ◽  
Fluoroquinolone Resistance ◽  
Whole Genome ◽  
Alternative Treatments ◽  
Genome Sequence Analysis ◽  
Global Priority

AbstractIncreasing antimicrobial resistance and limited alternative treatments led to fluoroquinolone resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterised multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

scholarly journals Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis

2020 ◽  
Vol 7 (11) ◽  
Author(s):  
Sarah Flohr ◽  
Alban Ramette ◽  
Philipp K A Agyeman ◽  
Andrea Duppenthaler ◽  
Cordula Scherer ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Genome Sequence ◽  
Surgical Therapy ◽  
Skin Infection ◽  
Whole Genome Sequence ◽  
Factitious Disorder ◽  
Whole Genome ◽  
Mycobacterium Chelonae ◽  
Genome Sequence Analysis ◽  
Adequate Therapy

Abstract Mycobacterium chelonae infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive M chelonae infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection from recurrence and contributed to the diagnosis of a factitious disorder.

scholarly journals Application of whole genome sequence analysis to the study of Mycobacterium tuberculosis in Nunavut, Canada

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185656 ◽  
Author(s):  
Andrea D. Tyler ◽  
Elaine Randell ◽  
Maureen Baikie ◽  
Kym Antonation ◽  
Debra Janella ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Sequence Analysis ◽  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Genome Sequence Analysis

Prevalence and Molecular Characterization of Novel Pathogenic Strains of Macrococcus Caseolyticus Isolated From External Wounds of Donkeys in Khartoum State –Sudan

2021 ◽  
Author(s):  
Dania Ali ◽  
Mushal Allam ◽  
Hisham Altayb ◽  
Dalia Mursi ◽  
M. A Abdalla ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Molecular Characterization ◽  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Genome Sequence Analysis ◽  
Resistant Genes ◽  
Different Seasons ◽  
Novel Alleles

Abstract A pathogenic strains of Macrococcus caseolyticus was isolated from wounds infection during investigation on donkeys in Khartoum State. Samples were collected from external wounds (head, abdomin, back and leg), during different seasons of the year. One isolate (124B) was identified using whole-genome sequence analysis. RAST software identified thirty-one virulent genes of disease and defense including methicillin resistant genes, TatR family and ANT(4’)-Ib. Plasmid rep22 wasidentified by PlasmidFindet-2.0 Server and a CRISPR. MILST-2.0 predicted many novel alleles. NCBI notated the genome as a novel strain of M.caseolyticus strain (DaniaSudan). The MLST-tree-V1 revealed that DaniaSudan and KM0211a strains were interrelated. Strain Daniasudan was resistant to ciprofloxacin, ceftazidime, erythromycin, oxacillin, clindamycin and kanamycin. The prevalence of the strain was 4.73%, with significant differences between collection seasons and locations of wounds. Mice modling showen bacteremia and many clinical (swelling, allergy, wounds and loss of hair). Enlarged, hyperemia, adhesions and abscesses were observed in many organs. This represents the first report of pathogenic strains of M.caseolyticus worldwide.

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