Hyperbaric oxygen treatment on diabetic foot and associated risk factors of lower limb amputation: Descriptive study

Objective.The aim of the study was to evaluate the prevalence of and risk factors for lower limb amputation in a specialist foot clinic-based setting.Methods.A retrospective quantitative study was conducted, using clinical and biochemical profiles of diabetic foot patients attending the High Risk Foot Clinic at The Townsville Hospital, Australia, between January 1, 2011, and December 31, 2013.Results.The total study sample included 129 subjects, comprising 81 males and 48 females with M : F ratio of 1.7 : 1. Twenty-three subjects were Indigenous Australians, representing 17.8% of the study population. The average age of the cohort was 63.4 years ± 14.1 years [CI 90.98–65.89]. Lower limb amputation was identified as a common and significant outcome (n=44), occurring in 34.1%, more commonly amongst the Indigenous Australians (56.5% versus 29.2%;p=0.94, OR 0.94). Risk factors most closely associated with amputation included diabetic retinopathy (p=0.00, OR 4.4), coronary artery bypass graft (CABG) surgery (p=0.01, OR 4.1), Charcot’s arthropathy (p=0.01, OR 2.9), and Indigenous ethnicity (p=0.01, OR 3.4). Although average serum creatinine, corrected calcium, and glycosylated haemoglobin A1c (Hba1c) levels were higher amongst amputees they were statistically insignificant.Conclusions.Lower limb amputation is a common outcome and linked to ethnicity and neurovascular diabetic complications amongst subjects with diabetic foot ulcer. Further research is needed to identify why risk of lower limb amputation seems to differ according to ethnicity.

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Fall incidence and associated risk factors among people with a lower limb amputation during various stages of recovery – a systematic review

Disability and Rehabilitation ◽

10.1080/09638288.2018.1449258 ◽

2018 ◽

Vol 41 (15) ◽

pp. 1778-1787 ◽

Cited By ~ 6

Author(s):

Noam Steinberg ◽

Amihai Gottlieb ◽

Itzhak Siev-Ner ◽

Meir Plotnik

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Lower Limb ◽

Lower Limb Amputation ◽

Limb Amputation ◽

Associated Risk Factors

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Evaluation of Prognostic Risk Factors in Patients with Diabetic Foot Ulcers Admitted to Sayyad Shirazi Hospital in Gorgan during 2018-2020

Tabari Biomedical Student Research Journal ◽

10.18502/tbsrj.v2i3.4527 ◽

2020 ◽

Author(s):

Roghieh Gholsha ◽

Zeynab Baylari ◽

Mohammad Tajik ◽

Ahmad Sohrabi ◽

Maryam Montazeri

Keyword(s):

Risk Factors ◽

Lower Limb ◽

Diabetic Foot ◽

Final Outcome ◽

Lower Limb Amputation ◽

Limb Amputation ◽

Chi Square ◽

History Of ◽

Prognostic Risk Factors ◽

The Relationship

Introduction: Diabetes mellitus (DM) is one of the most common diseases in the world and diabetic foot ulcer (DFU) is one of the main causes of mortality and morbidity. This study was done for the evaluation of prognostic risk factors in hospitalized patients with DFU. Material and Methods: In this cross-sectional study, the records of all patients with DFU referred to Sayyad Shirazi Hospital in Gorgan during 2018-2020 were reviewed to determine the demographic characteristics, paraclinical findings, and clinical features. All information of patients was entered into the checklist. Frequency, percentage, mean± standard deviation (SD) were used to describe the data. Chi-square and ANOVA tests were used to investigate the relationship between each. SPSS software version 20 was used for data analysis. Results: In this study 379 patient with DFU were studied that 54.1% were female. 62.3% of patients were in the age group of 45 -65 years. In these patients, 64.9% had hypertension and 37.7% had cardiovascular disease. 6.8% and 21.2% were smokers and drug addicts, respectively and 17.7% had history of lower limb amputation .76% of patient had grade 2 and 3 Wagner’s DFUs. According to the statistical analysis, there was no significant relationship between insulin treatment, smoking and opium use, and patientchr('39')s age with the final outcome of discharge. The chi-square test showed the relationship between white blood cells (WBCs) erythrocyte sedimentation rate (ESR) level and final outcome. Conclusion: DFU prognosis may be related to WBC and ESR, grading of DFU, and history of lower limb amputation.

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Limb- and Person-Level Risk Factors for Lower-Limb Amputation in the Prospective Seattle Diabetic Foot Study

Diabetes Care ◽

10.2337/dc17-2210 ◽

2018 ◽

Vol 41 (4) ◽

pp. 891-898 ◽

Cited By ~ 36

Author(s):

Edward J. Boyko ◽

Amber D. Seelig ◽

Jessie H. Ahroni

Keyword(s):

Risk Factors ◽

Lower Limb ◽

Diabetic Foot ◽

Lower Limb Amputation ◽

Limb Amputation

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The effect of hyperbaric oxygen treatment on late radiation tissue injury after breast cancer: A case-series of 67 patients

Diving and Hyperbaric Medicine Journal ◽

10.28920/dhm50.3.206-213 ◽

2020 ◽

Vol 50 (3) ◽

pp. 206-213

Author(s):

Nicole E Spruijt ◽

◽

Roy van den Berg ◽

Keyword(s):

Breast Cancer ◽

Risk Factors ◽

Hyperbaric Oxygen ◽

Tissue Injury ◽

Case Series ◽

Shoulder Abduction ◽

Hyperbaric Oxygen Treatment ◽

Normal Tissues ◽

Oxygen Treatment ◽

Shoulder Motion

Introduction: Late radiation tissue injury (LRTI) after breast cancer may benefit from hyperbaric oxygen treatment (HBOT). This study aimed to report the LRTI symptom scores up to 12 months after HBOT and identify risk factors for poor scores. Methods: A case-series of 67 patients who underwent a mean of 44 sessions of HBOT was analysed. LRTI symptoms were scored at four time points using the LENT-SOMA scale (Late Effects in Normal Tissues – Subjective, Objective, Management, and Analytic), a visual analog scale for pain, and the range of shoulder motion. Results: Between starting HBOT and 12 months after HBOT 57 patients (85%) reported at least one point improvement in their LENT-SOMA score. Median pain and fibrosis scores improved significantly between the start and end of HBOT (P < 0.001), and remained stable three and 12 months after HBOT. The median breast oedema score improved significantly 12 months after HBOT (P = 0.003). Median shoulder abduction increased significantly from 90 to 165 degrees (P = 0.001) and median shoulder anteflexion increased significantly from 115 to 150 degrees (P = 0.004). Various risk factors were identified for poor scores despite HBOT; the most common risk factor was a poor score at start of HBOT. Conclusions: In this case-series, patients who underwent HBOT for LRTI after breast cancer reported significant improvement in pain, fibrosis, oedema, and shoulder movement. The improvement persisted up to 12 months after HBOT. A poor score at the start of HBOT was predictive for a poor score 12 months after HBOT.

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