Prevalence and Risk Factors for Diabetic Lower Limb Amputation: A Clinic-Based Case Control Study

Objective.The aim of the study was to evaluate the prevalence of and risk factors for lower limb amputation in a specialist foot clinic-based setting.Methods.A retrospective quantitative study was conducted, using clinical and biochemical profiles of diabetic foot patients attending the High Risk Foot Clinic at The Townsville Hospital, Australia, between January 1, 2011, and December 31, 2013.Results.The total study sample included 129 subjects, comprising 81 males and 48 females with M : F ratio of 1.7 : 1. Twenty-three subjects were Indigenous Australians, representing 17.8% of the study population. The average age of the cohort was 63.4 years ± 14.1 years [CI 90.98–65.89]. Lower limb amputation was identified as a common and significant outcome (n=44), occurring in 34.1%, more commonly amongst the Indigenous Australians (56.5% versus 29.2%;p=0.94, OR 0.94). Risk factors most closely associated with amputation included diabetic retinopathy (p=0.00, OR 4.4), coronary artery bypass graft (CABG) surgery (p=0.01, OR 4.1), Charcot’s arthropathy (p=0.01, OR 2.9), and Indigenous ethnicity (p=0.01, OR 3.4). Although average serum creatinine, corrected calcium, and glycosylated haemoglobin A1c (Hba1c) levels were higher amongst amputees they were statistically insignificant.Conclusions.Lower limb amputation is a common outcome and linked to ethnicity and neurovascular diabetic complications amongst subjects with diabetic foot ulcer. Further research is needed to identify why risk of lower limb amputation seems to differ according to ethnicity.

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Hyperbaric oxygen treatment on diabetic foot and associated risk factors of lower limb amputation: Descriptive study

International Journal of Infectious Diseases ◽

10.1016/j.ijid.2014.03.1134 ◽

2014 ◽

Vol 21 ◽

pp. 346

Author(s):

J. Valbuena ◽

P. Burgueño ◽

J.L. Teja ◽

J.F. Gutierrez ◽

A. Arnaiz

Keyword(s):

Risk Factors ◽

Hyperbaric Oxygen ◽

Lower Limb ◽

Diabetic Foot ◽

Descriptive Study ◽

Lower Limb Amputation ◽

Limb Amputation ◽

Hyperbaric Oxygen Treatment ◽

Oxygen Treatment ◽

Associated Risk Factors

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Evaluation of Prognostic Risk Factors in Patients with Diabetic Foot Ulcers Admitted to Sayyad Shirazi Hospital in Gorgan during 2018-2020

Tabari Biomedical Student Research Journal ◽

10.18502/tbsrj.v2i3.4527 ◽

2020 ◽

Author(s):

Roghieh Gholsha ◽

Zeynab Baylari ◽

Mohammad Tajik ◽

Ahmad Sohrabi ◽

Maryam Montazeri

Keyword(s):

Risk Factors ◽

Lower Limb ◽

Diabetic Foot ◽

Final Outcome ◽

Lower Limb Amputation ◽

Limb Amputation ◽

Chi Square ◽

History Of ◽

Prognostic Risk Factors ◽

The Relationship

Introduction: Diabetes mellitus (DM) is one of the most common diseases in the world and diabetic foot ulcer (DFU) is one of the main causes of mortality and morbidity. This study was done for the evaluation of prognostic risk factors in hospitalized patients with DFU. Material and Methods: In this cross-sectional study, the records of all patients with DFU referred to Sayyad Shirazi Hospital in Gorgan during 2018-2020 were reviewed to determine the demographic characteristics, paraclinical findings, and clinical features. All information of patients was entered into the checklist. Frequency, percentage, mean± standard deviation (SD) were used to describe the data. Chi-square and ANOVA tests were used to investigate the relationship between each. SPSS software version 20 was used for data analysis. Results: In this study 379 patient with DFU were studied that 54.1% were female. 62.3% of patients were in the age group of 45 -65 years. In these patients, 64.9% had hypertension and 37.7% had cardiovascular disease. 6.8% and 21.2% were smokers and drug addicts, respectively and 17.7% had history of lower limb amputation .76% of patient had grade 2 and 3 Wagner’s DFUs. According to the statistical analysis, there was no significant relationship between insulin treatment, smoking and opium use, and patientchr('39')s age with the final outcome of discharge. The chi-square test showed the relationship between white blood cells (WBCs) erythrocyte sedimentation rate (ESR) level and final outcome. Conclusion: DFU prognosis may be related to WBC and ESR, grading of DFU, and history of lower limb amputation.

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