scholarly journals Prevalence of anti-hepatitis E virus immunoglobulin G in HIV-infected individuals over three decades

2019 ◽  
Vol 84 ◽  
pp. 67-72 ◽  
Author(s):  
Lene Holm Harritshøj ◽  
Ditte Marie Kirkegaard-Klitbo ◽  
Niels Mejer ◽  
Inge Panum ◽  
Sofie Elisabeth Midgley ◽  
...  
2008 ◽  
Vol 15 (4) ◽  
pp. 732-734 ◽  
Author(s):  
Maria Buti ◽  
Pere Plans ◽  
Angela Domínguez ◽  
Rossend Jardi ◽  
Francisco Rodriguez Frias ◽  
...  

ABSTRACT The prevalence of immunoglobulin G (IgG) anti-hepatitis E virus (anti-HEV) antibodies was studied with a representative sample of 1,249 healthy children aged between 6 and 15 years. IgG anti-HEV antibodies were detected in 57 (4.6%) of the 1,249 samples analyzed, suggesting that some children are exposed to HEV in early childhood.


2013 ◽  
Vol 85 (5) ◽  
pp. 828-832 ◽  
Author(s):  
Tejaswini M. Deshmukh ◽  
Rachita R. Shah ◽  
Yogesh K. Gurav ◽  
Vidya A. Arankalle

2012 ◽  
Vol 75 (8) ◽  
pp. 1483-1485 ◽  
Author(s):  
S. WACHECK ◽  
E. SARNO ◽  
E. MÄRTLBAUER ◽  
C. ZWEIFEL ◽  
R. STEPHAN

Hepatitis E virus (HEV) and Salmonella bacteria are zoonotic pathogens that can be acquired by foodborne transmission because food animals, for example pigs, are recognized as a reservoir. The objectives of this study were to determine the seroprevalence of anti-HEV immunoglobulin G (IgG) and anti-Salmonella antibodies from healthy pigs at slaughter in Switzerland, a country with a good health status of pig herds (e.g., eradication of enzootic pneumonia) compared with those of many countries in the European Union, and a rate of importation of live pigs that is very low (<1%). Based on pooled (diaphragm muscles from 3 to 5 animals per producer) meat juice samples, 120 (60%) of 200 and 8 (4%) of 200 samples were positive for anti-HEV IgG and anti-Salmonella antibodies, respectively. HEV seems to be highly prevalent among fattening pigs in Switzerland, whereas the low seroprevalence of anti-Salmonella IgG has not changed in recent years.


2000 ◽  
Vol 38 (11) ◽  
pp. 3915-3918 ◽  
Author(s):  
Chen-Chun Lin ◽  
Jaw-Ching Wu ◽  
Ting-Tsung Chang ◽  
Wen-Yu Chang ◽  
Ming-Lung Yu ◽  
...  

Acute hepatitis E (AHE) has rarely been reported in industrialized countries, but the rate of seroprevalence of hepatitis E virus (HEV) antibodies (anti-HEV) is inappropriately high. The sensitivity and specificity of the assay used to test for immunoglobulin G (IgG) and IgM anti-HEV have not been well established in areas where hepatitis E is not endemic (hereafter referred to as “nonendemic areas”). We collected serum samples from 13 AHE patients, 271 healthy subjects, and 160 other liver disease patients in Taiwan to test for HEV RNA by reverse transcription (RT)-PCR and for IgG and IgM anti-HEV by enzyme-linked immunosorbent assays. The sensitivities of IgG and IgM anti-HEV (relative to RT-PCR) were 86.7 and 53.3%, respectively. The specificities of IgG and IgM anti-HEV assays for diagnosing AHE were 92.1 and 98.6%, respectively. The rate of seroprevalence of IgG anti-HEV was 11% among healthy subjects in this nonendemic area, and it increased with age. In summary, IgG anti-HEV is a good diagnostic test for screening for AHE in nonendemic areas. The high rate of prevalence of anti-HEV in healthy subjects indicates that subclinical infection may exist.


Author(s):  
Nida ul Fatima ◽  
Rabia Anwar ◽  
Tahir Ahmed Baig ◽  
Khalid Mehmood ◽  
Saadia Andleeb

Abstract Objectives: To investigate the seroprevalence of hepatitis E virus infection, risk factors and its association with progesterone levels in pregnant women from low socioeconomic background. Methods: The cross-sectional study was conducted in Rawalpindi and Islamabad, Pakistan, from January to July 2012, and comprised pregnant asymptomatic healthy females from different clinics and hospitals of the twin cities. Data was collected using a predesigned demographic questionnaire to determine socioeconomic status. Prevalence of anti-hepatitis E virus antibodies and progesterone levels were determined using enzyme-linked immunosorbent assay kits. Results: Of the 90 women, 35(39%) were in the 21-25 year age group, and 55(61%) belonged to low socioeconomic background. The overall prevalence of seropositive hepatitis E virus immunoglobulin-G was 54(60%) and immunoglobulin-M was 12(13.3%). In the first trimester, the levels of progesterone were higher in patients positive for immunoglobulin-M compared to immunoglobulin-G (p<0.001). Conclusions: Low socioeconomic status appeared to be a potential risk factor associated with high hepatitis E virus seroprevalence and alterations in the normal progesterone levels during pregnancy. Key Words: Hepatitis E virus, HEV, Progesterone, Seroprevalence, Pakistan.


2011 ◽  
Vol 49 (01) ◽  
Author(s):  
C Dorloff ◽  
J Hemberger ◽  
M Odenthal ◽  
H Holzmann ◽  
S Aberle ◽  
...  

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