Serological evidence for tick-borne encephalitis, borreliosis, and human granulocytic anaplasmosis in Mongolia

2006 ◽  
Vol 296 ◽  
pp. 69-75 ◽  
Author(s):  
Gernot Walder ◽  
Erdenechimeg Lkhamsuren ◽  
Abmed Shagdar ◽  
Jantsandoo Bataa ◽  
Tsetsegsaikhan Batmunkh ◽  
...  
Keyword(s):  
Serological Evidence ◽  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis ◽  
Tick Borne Encephalitis

Bacterial tick-associated infections in Australia: current studies and future directions

2018 ◽  
Vol 39 (4) ◽  
pp. 200
Author(s):  
Peter Irwin ◽  
Siobhon Egan ◽  
Telleasha Greay ◽  
Charlotte Oskam
Keyword(s):  
Northern Hemisphere ◽  
Lyme Borreliosis ◽  
High Throughput ◽  
Diagnostic Methods ◽  
Future Directions ◽  
Human Granulocytic Anaplasmosis ◽  
Boutonneuse Fever ◽  
Granulocytic Anaplasmosis ◽  
Tick Borne Encephalitis ◽  
Shed Light

It may seem perplexing that there is any uncertainty in Australia about the existence of zoonotic tick-associated infections1–3. Outside this country, particularly in the northern hemisphere, tick-borne diseases such as human granulocytic anaplasmosis, babesiosis, Boutonneuse fever, ehrlichiosis, Lyme borreliosis, and tick-borne encephalitis, have well documented aetiologies, epidemiology, diagnostic methods, and treatments. Why is Australia different and what research is being conducted to address this issue? This article briefly addresses these questions and explains how high-throughput metagenomic analysis has started to shed light on bacterial microbiomes in Australian ticks, providing new data on the presence and distribution of potentially zoonotic microbial taxa.

scholarly journals Detection of antibodies against agents of human granulocytic anaplasmosis and human monocytic ehrlichiosis serum from patients from Novosibirsk Region

2008 ◽  
Vol 7 ◽  
pp. 73-77
Author(s):  
V. A. Rar ◽  
N. V. Fomenko ◽  
O. V. Mel’nikova ◽  
N. Ya. Chernousova
Keyword(s):  
Febrile Illness ◽  
Tick Bites ◽  
Serum Samples ◽  
Human Granulocytic Anaplasmosis ◽  
Specific Antibodies ◽  
Granulocytic Anaplasmosis ◽  
Novosibirsk Region ◽  
Tick Borne Encephalitis ◽  
Tick Borne Encephalitis Virus ◽  
Human Monocytic Ehrlichiosis

Serum samples from patients hospitalized with febrile illnesses occurring after tick bites were investigated for antibodies against agents of human granulocytic anaplasmosis (HGA) and human monocytic ehrlichiosis (HME). Ten from 205 patients were shown to contain HGA-specific antibodies, one patient — HME-specific antibodies, and one patient — both antibodies against agents of HGA and HME. Diagnosis of HGA was serologically and clinically confirmed for four patients. All patients with serologically confirmed HGA were shown to contain also antibodies against Borrelia burgdorferi sensu lato or HME-specific antibodies. Moreover, one patient was shown to be infected with tick-borne encephalitis virus. Thus, it seems reasonable to analyze patients with confirmed tick-borne encephalitis as well as with febrile illness after tick bites on the infection with HGA and HME.

scholarly journals CXCR2 Blockade Influences Anaplasma phagocytophilum Propagation but Not Histopathology in the Mouse Model of Human Granulocytic Anaplasmosis

2004 ◽  
Vol 11 (5) ◽  
pp. 963-968 ◽  
Author(s):  
Diana G. Scorpio ◽  
Mustafa Akkoyunlu ◽  
Erol Fikrig ◽  
J. Stephen Dumler
Keyword(s):  
Anaplasma Phagocytophilum ◽  
Tissue Injury ◽  
Treated Group ◽  
Obligate Intracellular Bacterium ◽  
Human Granulocytic Anaplasmosis ◽  
Obligate Intracellular ◽  
Liver Histopathology ◽  
Granulocytic Anaplasmosis ◽  
Infected Cells ◽  
And Control

ABSTRACT Anaplasma phagocytophilum is an obligate intracellular bacterium that infects neutrophils and causes human granulocytic anaplasmosis. Infection induces neutrophil secretion of interleukin-8 or murine homologs and perpetuates infection by recruiting susceptible neutrophils. We hypothesized that antibody blockade of CXCR2 would decrease A. phagocytophilum tissue load by interrupting neutrophil recruitment but would not influence murine hepatic pathology. C3H-scid mice were treated with CXCR2 antiserum or control prior to or on day 14 after infection. Quantitative PCR and immunohistochemistry for A. phagocytophilum were performed and severity of liver histopathology was ranked. Control mice had more infected cells in tissues than the anti-CXCR2-treated group. The histopathological rank was not different between treated and control animals. Infected cells of control mice clustered in tissue more than in treated mice. The results support the hypothesis of bacterial propagation through chemokine induction and confirm that tissue injury is unrelated to A. phagocytophilum tissue load.

scholarly journals Human Granulocytic Anaplasmosis Acquired in Scotland, 2013

2014 ◽  
Vol 20 (6) ◽  
pp. 1079-1081 ◽  
Author(s):  
Peter Hagedorn ◽  
Maren Imhoff ◽  
Christian Fischer ◽  
Cristina Domingo ◽  
Matthias Niedrig
Keyword(s):  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis

scholarly journals A Traumatic Tick Bite: A Case Report

2021 ◽  
Vol 2 (5) ◽  
pp. 210-213
Author(s):  
Daniel Finnin ◽  
Christopher Hanowitz
Keyword(s):  
Case Report ◽  
Symptomatic Improvement ◽  
Tick Bite ◽  
Facial Trauma ◽  
Laboratory Findings ◽  
Human Granulocytic Anaplasmosis ◽  
Presenting Symptoms ◽  
Granulocytic Anaplasmosis ◽  
Prophylactic Dose ◽  
Tick Borne Disease

Introduction: Human granulocytic anaplasmosis is a tick-borne disease with an increasing incidence associated with morbidity and mortality. Uncertainty remains whether a prophylactic dose of doxycycline is effective in prevention. Case Report: We present a case of an 80-year-old female with syncope, resultant facial trauma, and fever two weeks after a tick bite for which she received prophylaxis. Workup revealed anaplasmosis, and treatment led to symptomatic improvement. Conclusion: We review the presenting symptoms, laboratory findings, and treatment of anaplasmosis, as well as give caution about the limitations in prescribing a prophylactic dose of doxycycline following a tick bite.

First described case of human granulocytic anaplasmosis in a patient in Eastern Austria

2010 ◽  
Vol 160 (3-4) ◽  
pp. 91-93 ◽  
Author(s):  
Ursula Maria Vogl ◽  
Elisabeth Presterl ◽  
Gerold Stanek ◽  
Michael Ramharter ◽  
Klaus-Bernhard Gattringer ◽  
...  
Keyword(s):  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis ◽  
Eastern Austria
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