scholarly journals A Traumatic Tick Bite: A Case Report

2021 ◽  
Vol 2 (5) ◽  
pp. 210-213
Author(s):  
Daniel Finnin ◽  
Christopher Hanowitz
Keyword(s):  
Case Report ◽  
Symptomatic Improvement ◽  
Tick Bite ◽  
Facial Trauma ◽  
Laboratory Findings ◽  
Human Granulocytic Anaplasmosis ◽  
Presenting Symptoms ◽  
Granulocytic Anaplasmosis ◽  
Prophylactic Dose ◽  
Tick Borne Disease

Introduction: Human granulocytic anaplasmosis is a tick-borne disease with an increasing incidence associated with morbidity and mortality. Uncertainty remains whether a prophylactic dose of doxycycline is effective in prevention. Case Report: We present a case of an 80-year-old female with syncope, resultant facial trauma, and fever two weeks after a tick bite for which she received prophylaxis. Workup revealed anaplasmosis, and treatment led to symptomatic improvement. Conclusion: We review the presenting symptoms, laboratory findings, and treatment of anaplasmosis, as well as give caution about the limitations in prescribing a prophylactic dose of doxycycline following a tick bite.

scholarly journals 666. Human Granulocytic Anaplasmosis and Ehrlichiosis Presenting to an Upstate New York Emergency Department

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S241-S241
Author(s):  
Michael Waxman ◽  
Jennifer White ◽  
Elizabeth M Dufort ◽  
Abigale Eichelman ◽  
Kathleen Stellrecht ◽  
...  
Keyword(s):  
Emergency Department ◽  
New York ◽  
Medical Center ◽  
Tick Bite ◽  
Laboratory Findings ◽  
Positive Polymerase Chain Reaction ◽  
Human Granulocytic Anaplasmosis ◽  
North East ◽  
The North ◽  
Granulocytic Anaplasmosis

Abstract Background Human granulocytic anaplasmosis (HGA) is an increasingly common tickborne infection in the North-East United States. Statewide incidence of human cases of anaplasmosis in New York (excluding New York City) increased 407% from 2010–2017, with a corresponding increase in Anaplasma phagocytophilum prevalence in ticks. While previous observational studies have described the clinical features of HGA, there has been little documentation of HGA diagnosed in the emergency department (ED) setting. Methods Demographic and clinical data were extracted from electronic records of cases with a positive polymerase chain reaction (PCR) for HGA or the closely related clinical entity ehrlichiosis from 2016 to 2017. HGA and ehrlichiosis PCR were performed by the Albany Medical Center laboratory on patients treated in the ED. Basic descriptive analyses were performed. Results During the 2-year period, there were 37 cases of PCR-positive HGA and four cases of PCR-positive ehrlichiosis treated in the ED. Electronic data were available for extraction for 40 of these cases. Mean age was 54 years old (range 7–94 years). Thirty-four (85%) patients presented with fever, and 9 (23%) reported a tick bite or tick exposure. Twenty-two (55%) patients had leukopenia; 32 (80%) thrombocytopenia; 26 (65%) hyponatremia; 24 (60%) elevated transaminases; 38 (95%) at least one of these laboratory abnormality; and 13 (33%) all four laboratory abnormalities. Twenty-four patients (60%) were given the empiric diagnosis of a tickborne illness upon disposition from the ED, with 19 (48%) patients admitted to the hospital. Conclusion To our knowledge, this study represents the first description of patients diagnosed with HGA (and ehrlichiosis) in the ED setting. Because of the inherent testing bias, further study is needed to establish the true ED prevalence of HGA in highly endemic regions. Notably, only 23% reported either a tick bite or tick exposure, highlighting the need to consider this for diagnosis in patients presenting to the ED with consistent symptoms and laboratory findings in endemic areas. Further study might explore whether there exists a collection of laboratory findings that could accurately identify HGA in ED patients. Disclosures All authors: No reported disclosures.

Assessing the risk of human granulocytic anaplasmosis and lyme borreliosis after a tick bite in Bavaria, Germany

2015 ◽  
Vol 305 (7) ◽  
pp. 736-741 ◽  
Author(s):  
Beatrix von Wissmann ◽  
Wolfgang Hautmann ◽  
Andreas Sing ◽  
Cecilia Hizo-Teufel ◽  
Volker Fingerle
Keyword(s):  
Lyme Borreliosis ◽  
Tick Bite ◽  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis

Acute Kidney Injury Associated With Human Granulocytic Anaplasmosis: A Case Report

2019 ◽  
Vol 74 (5) ◽  
pp. 696-699
Author(s):  
Min Zhuo ◽  
Hila Calev ◽  
Staci J. Saunders ◽  
Jiahua Li ◽  
Isaac E. Stillman ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Case Report ◽  
Kidney Injury ◽  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis

scholarly journals Anchoring on COVID-19: A Case Report of Human Granulocytic Anaplasmosis Masquerading as COVID-19

2021 ◽  
Vol 5 (3) ◽  
pp. 328-331
Author(s):  
Mark Stice ◽  
Charles Bruen ◽  
Kristi Grall
Keyword(s):  
Case Report ◽  
Anaplasma Phagocytophilum ◽  
Inclusion Bodies ◽  
Severe Disease ◽  
Chain Reaction ◽  
Peripheral Smear ◽  
Severe Respiratory Distress ◽  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis ◽  
Polymerase Chain

Introduction: Human granulocytic anaplasmosis (HGA) is caused by Anaplasma phagocytophilum and transmitted through the deer tick. Most cases are mild and can be managed as an outpatient, but rare cases can produce severe symptoms. Case Report: A 43-year-old male presented with severe respiratory distress mimicking coronavirus disease 2019 (COVID-19). Labs and imaging were consistent with COVID-19; however, polymerase chain reaction was negative twice. Peripheral smear revealed inclusion bodies consistent with HGA. Conclusion: Human granulocytic anaplasmosis is an uncommon diagnosis and rarely causes severe disease. Recognition of unique presentations can aid in quicker diagnosis, especially when mimicking presentations frequently seen during the COVID-19 pandemic.

scholarly journals Severe Human Granulocytic Anaplasmosis With Significantly Elevated Ferritin Levels in an Immunocompetent Host in Pennsylvania: A Case Report

2018 ◽  
Vol 6 ◽  
pp. 232470961875835 ◽  
Author(s):  
Mona L. Camacci ◽  
Ronaldo Paolo Panganiban ◽  
Zachary Pattison ◽  
Kamyar Haghayeghi ◽  
Alexander Daly ◽  
...  
Keyword(s):  
Case Report ◽  
Immunocompetent Host ◽  
Human Granulocytic Anaplasmosis ◽  
Granulocytic Anaplasmosis

scholarly journals A review on the eco-epidemiology and clinical management of human granulocytic anaplasmosis and its agent in Europe

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Ioana A. Matei ◽  
Agustín Estrada-Peña ◽  
Sally J. Cutler ◽  
Muriel Vayssier-Taussat ◽  
Lucía Varela-Castro ◽  
...  
Keyword(s):  
Laboratory Tests ◽  
Clinical Signs ◽  
Epidemiologic Studies ◽  
Human Infection ◽  
Tick Bite ◽  
Human Granulocytic Anaplasmosis ◽  
Antibiotic Overuse ◽  
Granulocytic Anaplasmosis ◽  
The Usa ◽  
The Difference

AbstractAnaplasma phagocytophilum is the agent of tick-borne fever, equine, canine and human granulocytic anaplasmosis. The common route of A. phagocytophilum transmission is through a tick bite, the main vector in Europe being Ixodes ricinus. Despite the apparently ubiquitous presence of the pathogen A. phagocytophilum in ticks and various wild and domestic animals from Europe, up to date published clinical cases of human granulocytic anaplasmosis (HGA) remain rare compared to the worldwide status. It is unclear if this reflects the epidemiological dynamics of the human infection in Europe or if the disease is underdiagnosed or underreported. Epidemiologic studies in Europe have suggested an increased occupational risk of infection for forestry workers, hunters, veterinarians, and farmers with a tick-bite history and living in endemic areas. Although the overall genetic diversity of A. phagocytophilum in Europe is higher than in the USA, the strains responsible for the human infections are related on both continents. However, the study of the genetic variability and assessment of the difference of pathogenicity and infectivity between strains to various hosts has been insufficiently explored to date. Most of the European HGA cases presented as a mild infection, common clinical signs being pyrexia, headache, myalgia and arthralgia. The diagnosis of HGA in the USA was recommended to be based on clinical signs and the patient’s history and later confirmed using specialized laboratory tests. However, in Europe since the majority of cases are presenting as mild infection, laboratory tests may be performed before the treatment in order to avoid antibiotic overuse. The drug of choice for HGA is doxycycline and because of potential for serious complication the treatment should be instituted on clinical suspicion alone.

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