scholarly journals New insights into the use of a mite count reduction test for the detection of therapeutic acaricide efficacy in Psoroptes ovis in cattle

Author(s):  
Wouter van Mol ◽  
Edwin Claerebout ◽  
Stijn Casaert ◽  
Peter Geldhof ◽  
Bruno Levecke
2017 ◽  
Vol 37 (1) ◽  
pp. 47-51
Author(s):  
Rosângela R. dos Santos ◽  
Cristiane N. Coelho ◽  
Tiago A.P. Nunes ◽  
Lilian Cristina de S.O. Batista ◽  
Thaís R. Correia ◽  
...  

ABSTRACT: The present study evaluated the efficacy of a single oral dose of doramectin in the control of Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits. Sixteen adult rabbits were selected and distributed in two experimental groups. The treated group received 200 μg/Kg of oral doramectin and the control group received the same volume of saline solution. The diagnosis of the mites was made with a stereoscopic microscope. Hairs from the dorsal part of the neck, lumbar right, lumbar left, ventral side of the tail and ventral abdomen were evaluated for L. gibbus, and ear wax evaluated for P. ovis. The evaluation of the efficiency and the clinical assessment of the lesions was made in days 0, +3, +7, +14, +21, +28, and +35 after treatment. An efficacy of 75% and 87,5% was observed for L. gibbus in days +3 and +7 after treatment, an efficacy of 100% was observed in days +14, + 21, +28 e +35. An efficacy of 100% for the control of P. ovis was observed following day +7. The clinical lesion score of the control group remained unaltered, except for one animal which conditions worsened during experimentation. In the treated group animals, regression of the lesions was observed following day +3, and on day +21 no signal of infestation by P. ovis was present. None of the animals from the treated group presented secondary collateral effects caused by the doramectin, which proved itself as an optimal alternative for mite control in naturally infested rabbits.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Emily Joanne Nixon ◽  
Ellen Brooks-Pollock ◽  
Richard Wall

Abstract Background Ovine psoroptic mange (sheep scab) is a highly pathogenic contagious infection caused by the mite Psoroptes ovis. Following 21 years in which scab was eradicated in the UK, it was inadvertently reintroduced in 1972 and, despite the implementation of a range of control methods, its prevalence increased steadily thereafter. Recent reports of resistance to macrocyclic lactone treatments may further exacerbate control problems. A better understanding of the factors that facilitate its transmission are required to allow improved management of this disease. Transmission of infection occurs within and between contiguous sheep farms via infected sheep-to-sheep or sheep–environment contact and through long-distance movements of infected sheep, such as through markets. Methods A stochastic metapopulation model was used to investigate the impact of different transmission routes on the spatial pattern of outbreaks. A range of model scenarios were considered following the initial infection of a cluster of highly connected contiguous farms. Results Scab spreads between clusters of neighbouring contiguous farms after introduction but when long-distance movements are excluded, infection then self-limits spatially at boundaries where farm connectivity is low. Inclusion of long-distance movements is required to generate the national patterns of disease spread observed. Conclusions Preventing the movement of scab infested sheep through sales and markets is essential for any national management programme. If effective movement control can be implemented, regional control in geographic areas where farm densities are high would allow more focussed cost-effective scab management. Graphical Abstract


PEDIATRICS ◽  
1972 ◽  
Vol 49 (6) ◽  
pp. 854-859
Author(s):  
Giuseppe Russo ◽  
Florindo Mollica ◽  
Lorenzo Pavone ◽  
Gino Schilirò

Five female children who suffered hemolytic crises of favism were studied 10 to 20 months after crisis. Spectrophotometric assay of erythrocytic glucose-6-PD (G-6-PD) activity, methemoglobin reduction test, and three cytochemical methods of enzyme demonstration in individual erythrocytes were performed. The parents were also studied in the same way. Four girls were certainly heterozygotes for G-6-PD deficiency, and one was very probably a heterozygote. A relationship was found between severity of hemolytic crisis and degree of enzyme deficiency and percentage of enzyme devoid red cells. The G-6-PD levels during crisis were higher than out of crisis. Assumption of a selective lysis of enzymopenic red cells during crisis would seem justified. Heterozygotes with low percentages of enzymopenic red cells probably experience hemolytic processes without or with minimal clinical signs. Hence favism in females is probably more frequent than generally thought.


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