scholarly journals High speed DSC (hyper-DSC) as a tool to measure the solubility of a drug within a solid or semi-solid matrix

2005 ◽  
Vol 301 (1-2) ◽  
pp. 1-5 ◽  
Author(s):  
Daniela Gramaglia ◽  
Barbara R. Conway ◽  
Vicky L. Kett ◽  
R. Karl Malcolm ◽  
Hannah K. Batchelor
Keyword(s):  
2009 ◽  
Vol 24 (5) ◽  
pp. 750-752 ◽  
Author(s):  
Youfeng He ◽  
Shuming Xing ◽  
Shuisheng Xie ◽  
Guojie Huang ◽  
Lei Cheng ◽  
...  

2005 ◽  
Vol 27 (1) ◽  
pp. 12-16
Author(s):  
David N. Thomas ◽  
Thomas Mock

Every autumn a fundamental transition occurs in the surface waters of polar oceans. Millions of square kilometres of surface waters freeze to form an ice layer that varies from a few centimetres through to several metres thick, and which effectively separates the ocean from the atmosphere above. Ice made from seawater is a porous, semi-solid matrix permeated by a labyrinth of brine channels and pores, and within these a diverse microbial assemblage, including viruses, Archaea, bacteria, flagellates and unicellular algae can thrive. These assemblages can reach such high abundances that the ice becomes a rich coffee colour. The microbial assemblages are in turn a rich food source for grazing protoplankton and zooplankton, especially in winter when food in the water column is scarce.


Metals ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 143
Author(s):  
Zhangxing Liu ◽  
Rongfeng Zhou ◽  
Wentao Xiong ◽  
Zilong He ◽  
Tao Liu ◽  
...  

Copper–tin alloys are widely used in the machining and molding of sleeves, bearings, bearing housings, gears, etc. They are a material used in heavy-duty, high-speed and high-temperature situations and subject to strong friction conditions due to their high strength, high modulus of elasticity, low coefficient of friction and good wear and corrosion resistance. Although copper–tin alloys are excellent materials, a higher performance of mechanical parts is required under extreme operating conditions. Plastic deformation is an effective way to improve the overall performance of a workpiece. In this study, medium-temperature compression tests were performed on a semi-solid CuSn10P1 alloy using a Gleeble 1500D testing machine at different temperatures (350−440 °C) and strain rates (0.1−10 s−1) to obtain its medium-temperature deformation characteristics. The experimental results show that the filamentary deformation marks appearing during the deformation are not single twins or slip lines, but a mixture of dislocations, stacking faults and twins. Within the experimental parameters, the filamentary deformation marks increase with increasing strain and decrease with increasing temperature. Twinning subdivides the grains into lamellar sheets, and dislocation aggregates are found near the twinning boundaries. The results of this study are expected to make a theoretical contribution to the forming of copper–tin alloys in post-processing processes such as rolling and forging.


2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 2042-2042 ◽  
Author(s):  
A. I. B. Benson ◽  
E. Rubin ◽  
S. Beers ◽  
P. Mucci-Lorusso ◽  
W. Vermuelen ◽  
...  

2022 ◽  
Vol 327 ◽  
pp. 105-110
Author(s):  
Ting Sun ◽  
Yong Jin Wang ◽  
Ren Bo Song ◽  
Ya Zheng Liu ◽  
Jun Yanagimoto ◽  
...  

In this paper, the fundamental microstructure evolution of M2 high speed steel was investigated during semi-solid controlled cooling and conventional cooling, respectively. Semi-solid controlled cooling was conducted at 1260 °C with cooling rates from 0.1 to 10 °C/s, while conventional cooling was conducted at 1200 °C and 890 °C with different cooling rates. The continuous cooling transformation curves were plot according to the microstructure evolution. The results showed that microstructure transformation behavior of cooling structure in semi-solid temperature range was different from that of conventional process. For semi-solid specimen, the solid austenite dissolved more alloy elements, and the austenite stability was increased. The solid matrix was pearlite structure in the samples with cooling rate of 0.1 °C /s. When the cooling rate reached 1 °C/s, the granular pearlite disappeared and martensite lath was formed. The structure was relatively uniform, on which there were large carbide with regular shape. The solidified liquid phase showed a network shape surrounding the solid particles. The size of solid particles showed a decreasing trend with the increase of cooling rates. For conventional cooling process, the large eutectic M6C carbide and the small precipitated MC carbide could not be dissolved by austenitized at 890 °C. Increasing the austenitization temperature helped dissolving part of the carbides. The hardenability of M2 steel was high. The hardness has increased to a high level for both semi-solid and conventional specimens when cooling rate reached 1 °C/s. No obvious increase happened when cooling rate continued increasing.


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