The Mitogen-activated Protein Kinase (MAPK)/Extracellular Signal-regulated Kinase (ERK) 1/2 Kinase Inhibitor, AZD6244 (ARRY-142886) Enhances Radiosensitivity by Interfering with Radiation-induced TGF-alpha Signaling

Extracellular Signal ◽

Radiation Induced

Cutaneous Reactions in Children Treated with the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase Inhibitor Trametinib for Neural Tumors

Pediatric Dermatology ◽

10.1111/pde.13038 ◽

2016 ◽

Vol 34 (1) ◽

pp. 90-94 ◽

Cited By ~ 9

Author(s):

Christina Boull ◽

Kristen Hook ◽

Christopher Moertel ◽

Sheilagh Maguiness

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Extracellular Signal ◽

Cutaneous Reactions

The Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibitor PD184352 (CI-1040) Selectively Induces Apoptosis in Malignant Schwannoma Cell Lines

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.105.091454 ◽

2005 ◽

Vol 316 (1) ◽

pp. 456-465 ◽

Cited By ~ 47

Author(s):

Raymond R. Mattingly ◽

Janice M. Kraniak ◽

Joshua T. Dilworth ◽

Patricia Mathieu ◽

Beverly Bealmear ◽

...

Keyword(s):

Protein Kinase ◽

Cell Lines ◽

Kinase Inhibitor ◽

Malignant Schwannoma ◽

Extracellular Signal ◽

Induction of HL-60 cell differentiation by the p38 mitogen-activated protein kinase inhibitor SB203580 is mediated through the extracellular signal-regulated kinase signaling pathway

Anti-Cancer Drugs ◽

10.1097/00001813-200301000-00005 ◽

2003 ◽

Vol 14 (1) ◽

pp. 31-38 ◽

Cited By ~ 8

Author(s):

Jin-Xia Zhang ◽

Wie-Jian Zhuang ◽

Ka-Hung Poon ◽

Michael Yang ◽

Wang-Fun Fong

Keyword(s):

Cell Differentiation ◽

Protein Kinase ◽

Signaling Pathway ◽

Kinase Inhibitor ◽

Protein Kinase Inhibitor ◽

Extracellular Signal ◽

Kinase Signaling Pathway

Induction of Bim Expression Contributes to the Antitumor Synergy Between Sorafenib and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibitor CI-1040 in Hepatocellular Carcinoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-08-3294 ◽

2009 ◽

Vol 15 (18) ◽

pp. 5820-5828 ◽

Cited By ~ 26

Author(s):

Da-Liang Ou ◽

Ying-Chun Shen ◽

Ja-Der Liang ◽

Jun-Yang Liou ◽

Sung-Liang Yu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Protein Kinase ◽

Kinase Inhibitor ◽

Extracellular Signal ◽

E6201 [(3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase (MEK)-1 and MEK Kinase-1: In Vitro Characterization of Its Anti-Inflammatory and Antihyperproliferative Activities

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.109.156554 ◽

2009 ◽

Vol 331 (2) ◽

pp. 485-495 ◽

Cited By ~ 37

Author(s):

Masaki Goto ◽

Jesse Chow ◽

Kenzo Muramoto ◽

Ken-ichi Chiba ◽

Satoshi Yamamoto ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

In Vitro Characterization ◽

Extracellular Signal ◽

Anti Inflammatory

HA1077, a Rho kinase inhibitor, suppresses glioma-induced angiogenesis by targeting the Rho-ROCK and the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signal pathways

Cancer Science ◽

10.1111/j.1349-7006.2010.01794.x ◽

2010 ◽

Vol 102 (2) ◽

pp. 393-399 ◽

Cited By ~ 31

Author(s):

Hiromichi Nakabayashi ◽

Keiji Shimizu

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Rho Kinase ◽

Signal Pathways ◽

Extracellular Signal ◽

Rho Kinase Inhibitor ◽

Protein Kinase Kinase

E6201, a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase-1 and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Kinase-1: In Vivo Effects on Cutaneous Inflammatory Responses by Topical Administration

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.168583 ◽

2010 ◽

Vol 335 (1) ◽

pp. 23-31 ◽

Cited By ~ 15

Author(s):

Kenzo Muramoto ◽

Masaki Goto ◽

Yoko Inoue ◽

Naoto Ishii ◽

Ken-ichi Chiba ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Inflammatory Responses ◽

Topical Administration ◽

Extracellular Signal ◽

In Vivo Effects

Inhibition of Vascular Smooth Muscle Cell Proliferation and Neointimal Formation in Injured Arteries by a Novel, Oral Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Inhibitor

Circulation ◽

10.1161/01.cir.0000147773.86866.cd ◽

2004 ◽

Vol 110 (21) ◽

pp. 3367-3371 ◽

Cited By ~ 57

Author(s):

Giuseppa Gennaro ◽

Catherine Ménard ◽

Sophie-Élise Michaud ◽

Denis Deblois ◽

Alain Rivard

Keyword(s):

Cell Proliferation ◽

Smooth Muscle ◽

Protein Kinase ◽

Smooth Muscle Cell ◽

Kinase Inhibitor ◽

Neointimal Formation ◽

Extracellular Signal ◽

198 HIGH MOLECULAR WEIGHT HYALURONIC ACID INHIBITS IL-6-INDUCED MATRIX METALLOPROTEINASES PRODUCTION BY UP-REGULATING THE EXTRACELLULAR SIGNAL-REGULATED KINASE INHIBITOR MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASE-1

Osteoarthritis and Cartilage ◽

10.1016/s1063-4584(10)60225-7 ◽

2010 ◽

Vol 18 ◽

pp. S94

Author(s):

M. Hashizume ◽

M. Mihara

Keyword(s):

Molecular Weight ◽

Hyaluronic Acid ◽

Protein Kinase ◽

Matrix Metalloproteinases ◽

High Molecular Weight ◽

Kinase Inhibitor ◽

Extracellular Signal ◽

Faculty Opinions recommendation of Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1006218.77810 ◽

2002 ◽

Author(s):

Angel Nebreda

Keyword(s):

Protein Kinase ◽

Premature Senescence ◽

Oncogenic Ras ◽

Extracellular Signal ◽

Sequential Activation