scholarly journals A Lot to a Little or a Little to a Lot—Which Dose-Volume Relationship Ensures the Best Clinical Outcome in the High-Dose Radiation Therapy of Thoracic Tumors? A Prospective Approach

Author(s):  
C. Schroeder ◽  
R. Engenhart-Cabillic ◽  
A. Buchali
2016 ◽  
Vol 8 (8) ◽  
pp. 2053-2060 ◽  
Author(s):  
Christina Schröder ◽  
Rita Engenhart-Cabillic ◽  
Hilke Vorwerk ◽  
Michael Schmidt ◽  
Winfried Huhnt ◽  
...  

Radiology ◽  
1979 ◽  
Vol 132 (3) ◽  
pp. 717-719 ◽  
Author(s):  
R. William Morris ◽  
Rushdy Abadir

2020 ◽  
Vol 10 (4) ◽  
pp. e255-e263 ◽  
Author(s):  
Bram D. Vermeulen ◽  
Paul M. Jeene ◽  
Jasmijn Sijben ◽  
Robin Krol ◽  
Heidi Rütten ◽  
...  

Author(s):  
Laura A. Dawson ◽  
Sameh Hashem ◽  
Alexis Bujold

Overview: Stereotactic body radiotherapy (SBRT), in which highly conformal potent radiation doses are delivered in fewer fractions than traditional radiation therapy (RT), is an increasingly popular treatment for hepatocellular carcinoma (HCC). The great majority of HCCs smaller than 6 cm and with Child-Pugh A liver function are controlled with SBRT with limited toxicity. Long-term local control is reduced in larger tumors, and toxicity is increased in patients with Child-Pugh B or C liver function. SBRT is an effective treatment for tumor vascular thrombi and can lead to sustained vascular recanalization. The first site of recurrence following SBRT is most often within the liver, away from the high dose volume, providing rationale for combining SBRT with regional or systemic therapies. Randomized trials of SBRT are warranted.


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