Isolation, identification and characterization of apigenin from Justicia gendarussa and its anti-inflammatory activity

2018 ◽  
Vol 59 ◽  
pp. 157-167 ◽  
Author(s):  
K.S. Kumar ◽  
V. Sabu ◽  
G. Sindhu ◽  
A.A. Rauf ◽  
A. Helen
Marine Drugs ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 147 ◽  
Author(s):  
Cássio R. M. Souza ◽  
Wallace P. Bezerra ◽  
Janeusa T. Souto

Alkaloids are nitrogenous compounds with various biological activities. Alkaloids with anti-inflammatory activity are commonly found in terrestrial plants, but there are few records of the identification and characterization of the activity of these compounds in marine organisms such as fungi, bacteria, sponges, ascidians, and cnidarians. Seaweed are a source of several already elucidated bioactive compounds, but few studies have described and characterized the activity of seaweed alkaloids with anti-inflammatory properties. In this review, we have gathered the current knowledge about marine alkaloids with anti-inflammatory activity and suggest future perspectives for the study and bioprospecting of these compounds.


2009 ◽  
Vol 20 (6) ◽  
pp. 1060-1064 ◽  
Author(s):  
Rita C. S. Nunomura ◽  
Viviane G. Oliveira ◽  
Saulo L. Da Silva ◽  
Sergio M. Nunomura

Author(s):  
Snigdha Pattnaik ◽  
Laxmidhar Moharana

Anti-inflammatory refers to group of medication that is utilized for curing pain and inflammation. Many synthetic products are used as anti-inflammatory agents but the effects caused by them is not satisfactory. Cordis obliqua is an anti-inflammatory herb that is enormously involved in pain reduction. The present paper aims to develop a topical gel formulation comprising herbs i.e. Cordis obliqua and curcumin with potent anti-inflammatory activity. The gel formulation was then subjected to characterization studies which involve pH, viscosity, excrudability, spreadability and in vitro analysis. pH of gel formulation was found to be 7.2±1.01 which is almost equivalent to the skin pH. In viscosity test, it was observed that viscosity of gel formulation was found to be effective. Moreover, spreadability co-efficient of the formulation satisfactory which indicates that sanitizer gel easily adhers on the skin and covers the bacteria residing on the skin, if any.


1996 ◽  
Vol 10 (7) ◽  
pp. 451-459 ◽  
Author(s):  
John L Wallace

The toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) in the gastrointestinal tract continues to be a major limitation to their use in the treatment of inflammatory disorders. Better understanding of the pathogenesis of NSAID enteropathy has facilitated the development of novel NSAIDs that spare the gastrointestinal tract. In particular, identification and characterization of the inducible form of prostaglandin synthase has led to the design of novel NSAIDs that specifically target that enzyme. The pathogenesis of NSAID gastroenteropathy is reviewed, as are the strategies that have been used in the past and are used now to develop NSAIDs that spare the gastrointestinal tract. Also reviewed are the strategies being employed to achieve this goal in the future.


2005 ◽  
Vol 54 (9) ◽  
pp. 505-512 ◽  
Author(s):  
Nobuhiro ZAIMA ◽  
Tatsuya SUGAWARA ◽  
Hirofumi ARAI ◽  
Kazuyuki NAKAMURA ◽  
Mikako TAKASUGI ◽  
...  

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