15813 Epidemiologic studies of herpes simplex virus infections of type 1 and type 2 in Korea: A retrospective single-center study

Key points 1. This is the first report of adult primary herpetic oropharyngitis in the view point of the differences between the two types of herpes simplex virus (HSV). 2. 41 (25 type 1 and 16 type 2) HSV specific antigen positive cases among 68 immunoserologically confirmed adult HSV primary infection cases were investigated. 3. Significantly low incidence of oral lesions and high incidence of nausea were seen in HSV type 2 oropharyngitis cases, that might mean particular correlation vagus nerve and HSV type 2. 4. Significantly increased white blood cell count and high C-reacative protein value were seen in oropharyngitis by HSV type 2. 5. HSV type 2 possibly cause more severe symptoms and higher inflammatory reactions than type 1, without oral lesions.

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Proportion of Herpes Simplex Virus (HSV) Type 1 and Type 2 Among Genital and Extragenital HSV Isolates

Acta Dermato Venereologica ◽

10.1080/00015550252948158 ◽

2002 ◽

Vol 82 (2) ◽

pp. 118-120 ◽

Cited By ~ 33

Author(s):

Gun-Britt Löwhagen ◽

Petra Tunbäck ◽

Tomas Bergström

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Simplex Virus

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Typing of Clinical Herpes Simplex Virus Type 1 and Type 2 Isolates with Monoclonal Antibodies

Journal of Clinical Microbiology ◽

10.1128/jcm.37.8.2717-2718.1999 ◽

1999 ◽

Vol 37 (8) ◽

pp. 2717-2718 ◽

Cited By ~ 13

Author(s):

Jan-Åke Liljeqvist ◽

Bo Svennerholm ◽

Tomas Bergström

Keyword(s):

Monoclonal Antibody ◽

Monoclonal Antibodies ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Glycoprotein C ◽

Glycoprotein G ◽

Simplex Virus ◽

Hsv 1

The purpose of this study was to evaluate the performance of a herpes simplex virus (HSV) type 1-specific anti-glycoprotein C-1 monoclonal antibody (MAb) and a type 2-specific anti-glycoprotein G-2 MAb for typing of 2,400 clinical HSV-1 isolates and 2,400 clinical HSV-2 isolates, respectively, using an enzyme immunoassay. The anti-HSV-1 MAb showed sensitivity and specificity of 100%, and the anti-HSV-2 MAb showed a sensitivity of 99.46% and 100% specificity, indicating that these MAbs are suitable for typing of clinical HSV isolates.

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Retrospective analysis of prescriptions in the management of lepra reactions: Results of a single center study from tertiary hospital in Maharashtra

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i5.17346 ◽

2017 ◽

Vol 10 (5) ◽

pp. 191

Author(s):

Madhuri Kulkarni ◽

Anant Patil ◽

Siddharth Aathawale

Keyword(s):

Retrospective Study ◽

Antimicrobial Agent ◽

Retrospective Analysis ◽

Tertiary Hospital ◽

Single Center ◽

Single Center Study ◽

Multibacillary Leprosy ◽

Center Study

Objective: To examine pattern of lepra reaction andmedicines used in the treatment of lepra reactions in a tertiary hospital. Material methods: In this retrospective study, prescriptions of patients treated for the lepra reactions were reviewed to find out prevalence of type 1 and type 2 reactions and medicines used in the treatment of lepra reactions. Results:A total of66 patients (male 59.1%; female 40.9%) with mean age of 36.6 (+13.1) years were included in the study. Multibacillary leprosy was present in 93.7% patients. A total of 39 (60%) patients had type 2 reaction whereas 26 (40%) had type 1 reaction. Mean number of medicines per patients was 7.5. Prednisolone was used in 62 (93.9%) patients with mean duration of 33.32 (+33.2) days whereas chloroquine was used in 52 (78.8%) patients for 36.6 (+27.9) days. Thalidomide was used in 25 (37.9%) patients. Analgesic and anti-inflammatory and anti-acidity drugs were used in 63 (95.4%) patients each whereas paracetamol was given to 41 (62.1%) patients. Antihistamine, antimicrobial agent and vitamins were given to 27 (40.9%), 27 (40.9%) and 35 (53.0%) patients respectively. Conclusion:Lepra 2 reaction is more common than lepra 1 reaction. Prednisolone and chloroquine are the two most commonly used medicines in the treatment of lepra reaction. Similarly, thalidomide, older drug has emerged as common treatment for lepra reaction.

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