The mental health of Chinese women with polycystic ovary syndrome is related to sleep disorders, not disease status

2021 ◽  
Vol 282 ◽  
pp. 51-57
Author(s):  
Yin Yang ◽  
Hui Deng ◽  
Tian Li ◽  
Min Xia ◽  
Chang Liu ◽  
...  
Keyword(s):  
Mental Health ◽  
Polycystic Ovary Syndrome ◽  
Sleep Disorders ◽  
Chinese Women ◽  
Polycystic Ovary ◽  
Disease Status ◽  
Ovary Syndrome

scholarly journals The correlation between mental health and number of symptoms endorsed on a review of systems form in polycystic ovary syndrome

2018 ◽  
Vol 110 (4) ◽  
pp. e114
Author(s):  
V. Sundaram ◽  
E. Greenwood ◽  
H. Huddleston
Keyword(s):  
Mental Health ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome

scholarly journals A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndrome

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0144072 ◽  
Author(s):  
Lin Li ◽  
Chengyan Li ◽  
Ping Pan ◽  
Xiaoli Chen ◽  
Xiaoke Wu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Polycystic Ovary Syndrome ◽  
Chinese Women ◽  
Polycystic Ovary ◽  
Ovulation Rate ◽  
Metabolic Profiles ◽  
Ovary Syndrome ◽  
Menstrual Pattern

scholarly journals Women’s experiences of diagnosis and management of polycystic ovary syndrome: a mixed-methods study in general practice

2020 ◽  
Vol 70 (694) ◽  
pp. e322-e329 ◽  
Author(s):  
Sarah C Hillman ◽  
Carol Bryce ◽  
Rachel Caleychetty ◽  
Jeremy Dale
Keyword(s):  
Mental Health ◽  
General Practice ◽  
Mixed Methods ◽  
Polycystic Ovary Syndrome ◽  
Mental Health Problems ◽  
Polycystic Ovary ◽  
Mixed Methods Study ◽  
Ovary Syndrome ◽  
Women’S Experiences ◽  
Women's Experiences

BackgroundPolycystic ovary syndrome (PCOS) is a common lifelong metabolic condition with serious associated comorbidities. Evidence points to a delay in diagnosis and inconsistency in the information provided to women with PCOS.AimTo capture women’s experiences of how PCOS is diagnosed and managed in UK general practice.Design and settingThis was a mixed-methods study with an online questionnaire survey and semi-structured telephone interviews with a subset of responders.MethodAn online survey to elicit women’s experiences of general practice PCOS care was promoted by charities and BBC Radio Leicester. The survey was accessible online between January 2018 and November 2018. A subset of responders undertook a semi-structured telephone interview to provide more in-depth data.ResultsA total of 323 women completed the survey (average age 35.4 years) and semi-structured interviews were conducted with 11 women. There were five key themes identified through the survey responses. Participants described a variable lag time from presentation to PCOS diagnosis, with a median of 6–12 months. Many had experienced mental health problems associated with their PCOS symptoms, but had not discussed these with the GP. Many were unable to recall any discussion about associated comorbidities with the GP. Some differences were identified between the experiences of women from white British backgrounds and those from other ethnic backgrounds.ConclusionFrom the experiences of the women in this study, it appears that PCOS in general practice is not viewed as a long-term condition with an increased risk of comorbidities including mental health problems. Further research should explore GPs’ awareness of comorbidities and the differences in PCOS care experienced by women from different ethnic backgrounds.

scholarly journals Association analysis between the polymorphisms of HSD17B5 and HSD17B6 and risk of polycystic ovary syndrome in Chinese population

2015 ◽  
Vol 172 (3) ◽  
pp. 227-233 ◽  
Author(s):  
Rong Ju ◽  
Wei Wu ◽  
Juan Fei ◽  
Yufeng Qin ◽  
Qiuqin Tang ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Chinese Population ◽  
Chinese Women ◽  
Polycystic Ovary ◽  
Control Group ◽  
Model Assessment ◽  
Nucleotide Polymorphisms ◽  
Ovary Syndrome ◽  
Significant Difference ◽  
High Level

ObjectiveTo assess whether single nucleotide polymorphisms of HSD17B5 (AKR1C3) (rs1937845 and rs12529) and HSD17B6 (rs898611) are associated with polycystic ovary syndrome (PCOS) in a Chinese population.DesignA case–control study was conducted to investigate the relation between HSD17B5 and HSD17B6 polymorphisms and PCOS.MethodsIn this study, 335 patients with PCOS and 354 controls were recruited. The genotypes of HSD17B5 (rs1937845 and rs12529) and HSD17B6 (rs898611) were detected by the TaqMan method.Results and conclusionsWe found that the genotypic frequencies of the rs1937845 polymorphism were different in subjects with PCOS compared with control, with the CT genotype being more commonly found in patients with PCOS than in controls (P=0.005). We observed a significantly 1.74-fold higher risk of CT genotype in the polymorphism rs1937845 in women with PCOS vs the control group (adjusted odds ratio (OR), 1.74; 95% CI=1.19–2.54; P=0.005). A similar, significant 1.47-fold higher risk (adjusted OR, 1.47; 95% CI=1.07–2.03; P=0.018) was demonstrated for T allele of polymorphism rs1937845 associated with PCOS. In patients with PCOS, the rs12529 (G>C) and rs1937845 (C>T) polymorphisms were strongly associated with the high level of testosterone. The TT carriers of polymorphism rs1937845 had a significantly increased homeostatic model assessment-B% (HOMA-B%) (P=0.045) and that might be associated with the high risk of insulin resistance. However, no significant difference was found in genotype or allele distributions of the polymorphisms rs12529 of HSD17B5 and rs898611 of HSD17B6 between patients with PCOS and controls. Additionally, the two polymorphisms of HSD17B5 are associated with hyperandrogenemia in patients with PCOS. In conclusion, our findings showed a significant statistical association between HSD17B5 rs1937845 and PCOS risk in Chinese women. The CT genotype and T allele frequency are influenced significantly to a higher extent in patients with PCOS than controls. Further studies are needed to confirm the results and find out the exact molecular mechanism of the polymorphism on the risk of hyperandrogenemia and PCOS.

Rate of polycystic ovary syndrome in mental health disorders: a systematic review

2021 ◽  
Author(s):  
Katie M. Douglas ◽  
Anna J. Fenton ◽  
Kate Eggleston ◽  
Richard J. Porter
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Mental Health Disorders ◽  
Ovary Syndrome ◽  
Health Disorders

The mental health of women with polycystic ovary syndrome: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Xican Yin ◽  
Yinan Ji ◽  
Cecilia Lai Wan Chan ◽  
Celia Hoi Yan Chan
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Ovary Syndrome

Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial

2019 ◽  
Vol 250 ◽  
pp. 51-56 ◽  
Author(s):  
Azade Shabani ◽  
Fatemeh Foroozanfard ◽  
Elham Kavossian ◽  
Esmat Aghadavod ◽  
Vahidreza Ostadmohammadi ◽  
...  
Keyword(s):  
Mental Health ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Controlled Trial ◽  
Ovary Syndrome ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Melatonin Administration ◽  
Genetic Profiles ◽  
Health Parameters
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