P1-605: THE EFFECTS OF PHYSICAL EXERCISE ON COGNITIVE FUNCTION AMONG OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT: THE MEDITATING ROLE OF DEPRESSIVE SYMPTOMS AND SLEEP QUALITY

Abstract Social relationships play an important role in cognitive health and aging. However, it is unclear how older adult’s cognitive function affects their everyday social interactions, especially for those with mild cognitive impairment (MCI). This study examined whether older adults with intact cognition vs. MCI differed in their daily social interactions. Community-dwelling older adults from the Einstein Aging Study (N=244, 70-91 yrs) reported their social interactions five times daily for 14 consecutive days using smartphones. Compared to those with normal cognitive function, older adults with MCI reported less frequent positive social interactions (p=0.012) and in-person social activities (p=0.006) on a daily basis. These two groups, however, did not show significant differences in their social relationships assessed by a conventional global questionnaire. The results support that, relative to global social relationships, daily social interactions are more sensitive, ecologically valid social markers that can facilitate the early detection of MCI.

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Effects of Physical Activity Program on cognitive function and sleep quality in elderly with mild cognitive impairment: A randomized controlled trial

Perspectives In Psychiatric Care ◽

10.1111/ppc.12324 ◽

2018 ◽

Vol 55 (3) ◽

pp. 401-408 ◽

Cited By ~ 4

Author(s):

Kerime Bademli ◽

Neslihan Lok ◽

Muammer Canbaz ◽

Sefa Lok

Keyword(s):

Physical Activity ◽

Randomized Controlled Trial ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Function ◽

Sleep Quality ◽

Controlled Trial ◽

Physical Activity Program ◽

Randomized Controlled ◽

Activity Program

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Effects of the biopsychosocial functional activity program on cognitive function for community older adults with mild cognitive impairment : A cluster‐randomized controlled trial

Nursing and Health Sciences ◽

10.1111/nhs.12772 ◽

2020 ◽

Vol 22 (4) ◽

pp. 1065-1075

Author(s):

Yen‐Chun Lin ◽

Chi‐Jane Wang ◽

Yin‐Fan Chang ◽

Jing‐Jy Wang

Keyword(s):

Older Adults ◽

Randomized Controlled Trial ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Function ◽

Functional Activity ◽

Controlled Trial ◽

Randomized Controlled ◽

Activity Program ◽

Cluster Randomized

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MULTIMODAL PERSONALIZED CHRONOTHERAPY IMPROVES SLEEP IN ADULTS WITH MILD COGNITIVE IMPAIRMENT: A RANDOMIZED TRIAL

Innovation in Aging ◽

10.1093/geroni/igz038.1342 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S367-S367

Author(s):

Ryan S Falck ◽

John R Best ◽

Jennifer C Davis ◽

Patrick Chan ◽

Daniel Backhouse ◽

...

Keyword(s):

Older Adults ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Sleep Quality ◽

Sleep Hygiene ◽

Sleep Fragmentation ◽

Control Group ◽

Significant Group ◽

Increased Risk ◽

Improve Sleep Quality

Abstract Poor sleep is common among older adults with Mild Cognitive Impairment (MCI) and may contribute to their increased risk for dementia. Chronotherapy is a set of intervention strategies which can improve sleep quality by strengthening the entrainment of the biological clock to the solar light-dark cycle, and includes strategies such as: 1) bright light therapy (BLT); 2) physical activity (PA); and 3) good sleep hygiene. Thus, in this 24-week randomized controlled trial (RCT; NCT02926157), we aimed to examine the efficacy of a multimodal, personalized chronotherapy intervention to improve sleep quality among older adults with MCI. Ninety-six older adults (65+ years) with MCI were randomized to either: 1) a multimodal personalized chronotherapy group (INT); or 2) a waitlist-plus-education control group (CON). Participants allocated to the INT received four once-weekly, general sleep hygiene education classes, followed by 20 weeks of 1) individually-timed BLT; and 2) bi-weekly, individually-tailored PA counselling in conjunction with receiving a consumer-available PA tracker (Fitbit® FlexTM). We found a significant group x time interaction for objectively measured sleep fragmentation (5.01; p< 0.01) and also for Pittsburgh Sleep Quality Index (PSQI) score (p= 0.03), such that the INT: 1) maintained sleep fragmentation while CON worsened at 12 weeks (p< 0.01); and 2) had improved PSQI score compared to CON at both 12 weeks (p< 0.01) and 24 weeks (p= 0.04). Our results provide novel evidence that a multimodal personalized chronotherapy approach may promote both objective and subjective aspects of sleep quality in older adults with MCI.

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