Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry

2009 ◽  
Vol 877 (30) ◽  
pp. 3865-3870 ◽  
Author(s):  
Susanne H. Kirsch ◽  
Jean-Pierre Knapp ◽  
Jürgen Geisel ◽  
Wolfgang Herrmann ◽  
Rima Obeid
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Stable Isotope ◽  
Ultra Performance Liquid Chromatography ◽  
Tandem Mass ◽  
Stable Isotope Dilution ◽  
Simultaneous Quantification ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Adenosyl Methionine

A sensitive method to determine melatonin in saliva by automated online in-tube solid-phase microextraction coupled with stable isotope-dilution liquid chromatography-tandem mass spectrometry

2017 ◽  
Vol 9 (21) ◽  
pp. 3134-3140 ◽  
Author(s):  
Atsushi Ishizaki ◽  
Akiko Uemura ◽  
Hiroyuki Kataoka
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Stable Isotope ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Tandem Mass ◽  
Stable Isotope Dilution ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Sensitive Method

Melatonin (MLT) plays important roles in regulating the sleep-wake cycle, and has many beneficial effects on health. A simple, rapid, and sensitive method was developed for the determination of MLT in human saliva by automated online in-tube solid-phase microextraction coupled with stable isotope-dilution liquid chromatography-tandem mass spectrometry.

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