Formation of monodisperse mesoporous silica microparticles via spray-drying

2014 ◽  
Vol 418 ◽  
pp. 225-233 ◽  
Author(s):  
Kathryn Waldron ◽  
Winston Duo Wu ◽  
Zhangxiong Wu ◽  
Wenjie Liu ◽  
Cordelia Selomulya ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Spray Drying ◽  
Silica Microparticles

On Spray Drying of Uniform Mesoporous Silica Microparticles

2016 ◽  
Vol 3 (2) ◽  
pp. 646-651 ◽  
Author(s):  
K. Waldron ◽  
Z. Wu ◽  
D. Zhao ◽  
X.D. Chen ◽  
C. Selomulya
Keyword(s):  
Mesoporous Silica ◽  
Spray Drying ◽  
Silica Microparticles

scholarly journals Towards 99mTc- and Re-Based Multifunctional Silica Platforms for Theranostic Applications

Inorganics ◽  
2019 ◽  
Vol 7 (11) ◽  
pp. 134 ◽  
Author(s):  
Michel A. Wuillemin ◽  
Michael J. Reber ◽  
Thomas Fox ◽  
Bernhard Spingler ◽  
Dominik Brühwiler ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
External Surface ◽  
High Potential ◽  
Medical Applications ◽  
Pore Surface ◽  
Radio Imaging ◽  
Radiation Properties ◽  
Silica Microparticles ◽  
Theranostic Applications

Taking advantage of the radiation properties of 99mTc and 186/188Re and the photophysical characteristics of the {M(CO)3}+ moiety (M = Re), we developed a multifunctional silica platform with the theranostic pair 99mTc/Re with high potential for (nano)medical applications. Starting with a general screening to evaluate the most suitable mesoporous silica construct and the development of appropriate chelate systems, multifunctional mesoporous silica microparticles (SBA-15) were synthesized. These particles act as a model towards the synthesis of the corresponding nanoconstructs. The particles can be modified at the external surface with a targeting function and labeled with the {M(CO)3}+ moiety (M = 99mTc, Re) at the pore surface. Thus, a silica platform is realized, whose bioprofile is not altered by the loaded modalities. The described synthetic procedures can be applied to establish a target-specific theranostic nanoplatform, which enables the combination of fluorescence and radio imaging, with the possibility of radio- and chemotherapy.

scholarly journals Functional Magnetic Mesoporous Silica Microparticles Capped with an Azo-Derivative: A Promising Colon Drug Delivery Device

Molecules ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 375 ◽  
Author(s):  
Adrián Teruel ◽  
Carmen Coll ◽  
Ana Costero ◽  
Daniel Ferri ◽  
Margarita Parra ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Delivery Device ◽  
Drug Delivery Device ◽  
Colon Drug Delivery ◽  
Silica Microparticles ◽  
Magnetic Mesoporous Silica

scholarly journals Electrophoretic deposition of mesoporous silica powder synthesized by spray-drying method

2011 ◽  
Vol 119 (1387) ◽  
pp. 168-172 ◽  
Author(s):  
Hideyuki NEGISHI ◽  
Ai MIYAMOTO ◽  
Keiji SAKAKI ◽  
Akira ENDO
Keyword(s):  
Mesoporous Silica ◽  
Spray Drying ◽  
Electrophoretic Deposition ◽  
Drying Method ◽  
Silica Powder

Efficacy of budesonide-loaded mesoporous silica microparticles capped with a bulky azo derivative in rats with TNBS-induced colitis

2019 ◽  
Vol 561 ◽  
pp. 93-101 ◽  
Author(s):  
Daniel Ferri ◽  
Ana M. Costero ◽  
Pablo Gaviña ◽  
Margarita Parra ◽  
Virginia Merino ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Microparticles

In vitro toxicological evaluation of mesoporous silica microparticles functionalised with carvacrol and thymol

2021 ◽  
pp. 112778
Author(s):  
Cristina Fuentes ◽  
Ana Fuentes ◽  
Hugh J. Byrne ◽  
José Manuel Barat ◽  
María José Ruiz
Keyword(s):  
Mesoporous Silica ◽  
Toxicological Evaluation ◽  
Silica Microparticles
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