Electrophoretic deposition of mesoporous silica powder synthesized by spray-drying method

The memory effect of lithium-ion batteries (LIBs) was first discovered in LiFePO4, but its origin and dependence are still not clear, which is essential for regulating the memory effect. In this paper, a home-made spray drying device was used to successfully synthesize LiFePO4 with an average particle size of about 1 μm, and we studied the influence of spray drying temperature on the memory effect of LiFePO4 in LIBs. The results showed that the increasing of spray drying temperature made the memory effect of LiFePO4 strengthen from 1.3 mV to 2.9 mV, while the capacity decreased by approximately 6%. The XRD refinement and FTIR spectra indicate that the enhancement of memory effect can be attributed to the increment of Li–Fe dislocations. This work reveals the dependence of memory effect of LiFePO4 on spray drying temperature, which will guide us to optimize the preparation process of electrode materials and improve the management system of LIBs.

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Preparation of Ce-doped yttrium aluminum garnet phosphor particles using spray drying method

Journal of Asian Ceramic Societies ◽

10.1080/21870764.2020.1860432 ◽

2020 ◽

pp. 1-8

Author(s):

Shao-Ju Shih ◽

Lewi Peter Richardo ◽

Kevin Indrawan Sucipto ◽

Zhi-Meng Wang

Keyword(s):

Spray Drying ◽

Yttrium Aluminum Garnet ◽

Drying Method ◽

Yttrium Aluminum

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Solid dispersion particles of tolbutamide prepared with fine silica particles by the spray-drying method

Powder Technology ◽

10.1016/j.powtec.2004.03.007 ◽

2004 ◽

Vol 141 (3) ◽

pp. 187-195 ◽

Cited By ~ 74

Author(s):

Hirofumi Takeuchi ◽

Shinsuke Nagira ◽

Hiromitsu Yamamoto ◽

Yoshiaki Kawashima

Keyword(s):

Spray Drying ◽

Solid Dispersion ◽

Silica Particles ◽

Drying Method

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Oxidization and reduction kinetics of a manganese oxygen carrier granulated with the spray drying method at a tonnage scale for chemical looping combustion

Fuel ◽

10.1016/j.fuel.2021.121267 ◽

2021 ◽

Vol 303 ◽

pp. 121267

Author(s):

Lei Liu ◽

Zhenshan Li ◽

Ningsheng Cai

Keyword(s):

Spray Drying ◽

Oxygen Carrier ◽

Chemical Looping Combustion ◽

Reduction Kinetics ◽

Chemical Looping ◽

Drying Method ◽

Kinetics Of

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Ultra-Low-Power Electrophoretic Deposition of Silica Powder with Nonflammable Organic Solvent

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.654.88 ◽

2015 ◽

Vol 654 ◽

pp. 88-93

Author(s):

Hideyuki Negishi

Keyword(s):

Power Consumption ◽

Low Power ◽

Electrophoretic Deposition ◽

Particle Concentration ◽

Deposition Time ◽

Ultra Low Power ◽

Silica Powder ◽

Inorganic Particles ◽

Uniform Coating ◽

Electrical Insulation Properties

Although conventional organic solvents are used in electrophoretic deposition (EPD) owing to several advantages, they are hazardous because of their inflammability or ignition properties. In contrast, hydrofluoro ether (HFE) is nonflammable, polar and possesses excellent electrical insulation properties. In this study, methoxy-nonafluorobutane (MNFB), which is one of HFE was used as the solvent for the EPD of silica powder. Because the density of MNFB is larger than water, sedimentation of inorganic particles is slow. The deposition behavior in MNFB was similar to the EPD in conventional solvents, and was controlled by tuning the applied voltage, deposition time, and particle concentration. A uniform coating was obtained. Notably, the power consumed in this process was significantly lower than that in the EPD using conventional solvents. The current density was of the order of 10 nA/cm2; therefore, the electric power consumption for EPD using MNFB was less than 0.1% of those using conventional solvents. Therefore, MNFB can be used as an effective solvent for EPD because it is nonflammable, allows the application of high voltage, and enables the deposition of particles with low power consumption.

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Inhalable Spray Dried Pro-Liposome Powder Containing Budesonide for Pulmonary Delivery

International Journal of Pharmaceutical Sciences and Nanotechnology ◽

10.37285/ijpsn.2021.14.4.3 ◽

2021 ◽

Vol 14 (4) ◽

pp. 5538-5548

Author(s):

Aliasgar J Kundawala ◽

Khushbu S Chauhan ◽

Harsha V Patel ◽

Swati K Kurtkoti

Keyword(s):

Drug Release ◽

Spray Drying ◽

Entrapment Efficiency ◽

Geometric Standard Deviation ◽

Drying Method ◽

Dry Powder ◽

Liposomal Drug ◽

Vesicle Size ◽

Aerodynamic Properties ◽

Spray Dried

Budesonide is an anti-asthmatic agent which is used to control the symptoms of asthma like bronchospasm, oedema. Drug delivered to lung through inhalation will provide systemic and local drug delivery at lower dose in chronic and acute diseases. Dry powder inhalers are the best choice for targeting the anti-asthmatic drugs through pulmonary route. The objective of the present study is to prepare inhalable lipid coated budesonide microparticles by spray drying method so effective delivery of budesonide to the lungs can be achieved. The microparticles in the form of dry powder were obtained by either spray drying liposomal drug suspension or lipid drug suspension. The liposomes were initially prepared by solvent evaporation method using Hydrogenated Soyabean Phosphatidylcholine and Cholesterol (1:1, 1:2, 2:1) as lipid carrier and then spray dried later with mannitol as bulking agent at different lipid to diluent ratio (1:1.25, 1:2.5 & 1:5). The liposomes and liposomal dry powder were evaluated for vesicle size, % entrapment efficiency, in vitro drug release studies, powder characteristics, aerosol performance and stability studies. The liposomes prepared showed vesicle size (2-8 µm), Entrapment efficiency (92.22%) at lipid: drug ratio of (2.5:1) and observed 80.41 % drug release in 24 hrs. Pro-liposomes prepared by spray drying of liposomal drug suspension (LSD1) showed emitted dose, mean mass aerodynamic diameter, geometric standard deviation and fine particle fraction of 99.01%, 3.12 µm, 1.78 and 43.5% along with good powder properties. The spray dried powder was found to be stable at 4 ± 2 °C & 65% ± 5 % RH. The inhalable microparticles containing Budesonide containing lipid dry powder was successfully prepared by spray drying method that showed good aerodynamic properties and stability with mannitol as diluent. The microparticles produced with this novel approach could deliver drug on target via inhalation route and also ease manufacture process at large scale in fewer production steps.

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