Perifoveal capillary network quantification in young diabetic patients with subclinical or no retinopathy

2018 ◽  
Vol 53 (3) ◽  
pp. 199-206 ◽  
Author(s):  
Zoi Kapsala ◽  
Aristofanis Pallikaris ◽  
Dimitrios Mamoulakis ◽  
Joanna Moschandreas ◽  
Georgios Bontzos ◽  
...  
Keyword(s):  
Capillary Network ◽  
Diabetic Patients ◽  
Perifoveal Capillary Network

Perifoveal Capillary Network in Patients with Acute Central Retinal Vein Occlusion

Ophthalmology ◽  
1997 ◽  
Vol 104 (1) ◽  
pp. 33-37 ◽  
Author(s):  
Andreas Remky ◽  
Sebastian Wolf ◽  
Hildegard Knabben ◽  
Oliver Arend ◽  
Martin Reim
Keyword(s):  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Capillary Network ◽  
Vein Occlusion ◽  
Perifoveal Capillary Network ◽  
Central Retinal Vein

Reliability and validity of digital assessment of perifoveal capillary network measurement using high-resolution imaging

2014 ◽  
Vol 98 (6) ◽  
pp. 726-729 ◽  
Author(s):  
Jacqueline Mendonça Lopes de Faria ◽  
Diego Andreazzi Duarte ◽  
Roger Fredy Larico Chavez ◽  
Angélica Moises Arthur ◽  
Rangel Arthur ◽  
...  
Keyword(s):  
High Resolution ◽  
Reliability And Validity ◽  
Network Measurement ◽  
Capillary Network ◽  
High Resolution Imaging ◽  
Digital Assessment ◽  
Resolution Imaging ◽  
Perifoveal Capillary Network

scholarly journals The relationship between perifoveal capillary ring alterations and visual acuity in diabetic retinopathy

2021 ◽  
pp. 3-3
Author(s):  
Nenad Petrovic ◽  
Dusan Todorovic ◽  
Suncica Sreckovic ◽  
Tatjana Sarenac-Vulovic ◽  
Svetlana Jovanovic ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Macular Thickness ◽  
Capillary Network ◽  
Significant Difference ◽  
The Impact ◽  
Perifoveal Capillary Network ◽  
Decrease In Visual Acuity ◽  
Macular Ischemia

Background / Aim. To investigate the impact of diabetic macular ischemia (DMI) on visual acuity (VA) through the analysis of perifoveal capillary network in various stages of diabetic retinopathy (Non Proliferative Diabetic Retinopathy-NPDR and Proliferative Diabetic Retinopathy-PDR). Methods. Qualitative and quantitative analysis of 143 angiograms of patients with different stages of diabetic retinopathy was performed. The degree of macular ischemia was assessed by the analysis of 2 parameters: perifoveal capillary ring i.e. Foveal avascular zone (FAZ) outline irregularity and capillary loss. Finally, a comparison was made between the degree of macular ischemia with the best corrected visual acuity, depending on macular thickness. Results. In the eyes with mild and moderate NPDR, without significant macular thickening, no statistically significant decrease of visual acuity, caused by macular ischemia, was noticed (p=0.81). Opposite, in subgroup with severe NPDR and PDR, without significant macular thickening, statistically significant difference was presented among eyes with moderate and severe macular ischemia comparing to eyes with lower grades of macular ischemia (p=0.021, p=0.018). In eyes with moderate NPDR and mild macular ischemia, the increase in macular thickness resulted in a statistically insignificant decrease in visual acuity compared to eyes with normal macular thickness (p=0.088). But in eyes with severe NPDR, any pathological increase in macular thickness caused a statistically significant decrease in visual acuity, regardless of the degree of macular ischemia (p=0.018-0.040). A similar relationship was also found in eyes with PDR (p=0.017-0.042). In eyes with statistically significant decrease of visual acuity, the most of the examined eyes (98%) had FAZ outline irregularity in nasal perifoveal subfield. Conclusion. In the absence of significant macular thickening, destruction of one-half of the perifoveal capillary network or greater is associated with reduced VA. The location of macular ischemic changes in the nasal parts of the perifoveal capillary ring plays a crucial role in its effects on visual function.

Intramuscular Nerve and Neuromuscular Junction Alteration In Extraocular Muscles of Diabetic Mice

1985 ◽  
Vol 43 ◽  
pp. 682-683
Author(s):  
Bruce R. Pachter
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Nerves ◽  
Sudden Onset ◽  
Extraocular Muscles ◽  
Diabetic Patients ◽  
Oculomotor Palsy ◽  
Third Nerve Palsy ◽  
Patients With Diabetes ◽  
Intramuscular Nerve ◽  
Oculomotor Nerves

Diabetes mellitus is one of the commonest causes of neuropathy. Diabetic neuropathy is a heterogeneous group of neuropathic disorders to which patients with diabetes mellitus are susceptible; more than one kind of neuropathy can frequently occur in the same individual. Abnormalities are also known to occur in nearly every anatomic subdivision of the eye in diabetic patients. Oculomotor palsy appears to be common in diabetes mellitus for their occurrence in isolation to suggest diabetes. Nerves to the external ocular muscles are most commonly affected, particularly the oculomotor or third cranial nerve. The third nerve palsy of diabetes is characteristic, being of sudden onset, accompanied by orbital and retro-orbital pain, often associated with complete involvement of the external ocular muscles innervated by the nerve. While the human and experimental animal literature is replete with studies on the peripheral nerves in diabetes mellitus, there is but a paucity of reported studies dealing with the oculomotor nerves and their associated extraocular muscles (EOMs).

A Comparison Between Sterological Point Counting and Digitizing Tablets

1985 ◽  
Vol 43 ◽  
pp. 666-667
Author(s):  
John M. Basgen ◽  
Eileen N. Ellis ◽  
S. Michael Mauer ◽  
Michael W. Steffes
Keyword(s):  
Electron Microscopy ◽  
Kidney Tissue ◽  
Volume Density ◽  
Diabetic Patients ◽  
Normal Kidney ◽  
Point Counting ◽  
Normal Kidney Tissue ◽  
Biopsy Specimens ◽  
Mitochondrial Volume ◽  
Kidney Lesions

To determine the efficiency of methods of quantitation of the volume density of components within kidney biopsies, techniques involving a semi-automatic digitizing tablet and stereological point counting were compared.Volume density (Vv) is a parameter reflecting the volume of a component to the volume that contains the component, e.g., the fraction of cell volume that is made up of mitochondrial volume. The units of Vv are μm3 /μm3.Kidney biopsies from 15 patients were used. Five were donor biopsies performed at the time of kidney transplantation (patients 1-5, TABLE 1) and were considered normal kidney tissue. The remaining biopsies were obtained from diabetic patients with a spectrum of diabetic kidney lesions. The biopsy specimens were fixed and embedded according to routine electron microscogy protocols. Three glomeruli from each patient were selected randomly for electron microscopy. An average of 12 unbiased and systematic micrographs were obtained from each glomerulus and printed at a final magnification of x18,000.

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