Sustainability framework for pharmaceutical manufacturing (PM): A review of research landscape and implementation barriers for circular economy transition

2021 ◽  
Vol 280 ◽  
pp. 124264 ◽  
Author(s):  
Kun Liang Ang ◽  
Eng Toon Saw ◽  
Wei He ◽  
Xuecheng Dong ◽  
Seeram Ramakrishna
2021 ◽  
Vol 13 (3) ◽  
pp. 1529
Author(s):  
Andrea Cantú ◽  
Eduardo Aguiñaga ◽  
Carlos Scheel

While there is ample research on the barriers and enablers for implementing circular economy (CE) in large companies and developed economies, scant research exists concerning the factors impacting CE implementation in small and medium enterprises (SMEs) in emerging economies. To address this gap, our research seeks to determine the internal and external barriers SMEs face when implementing CE initiatives in emerging economies and identify how they can leverage CE implementation through bottom-up approaches. We present a multiple-case study of five SMEs in Mexico. Our findings suggest that the lack of regional enabling conditions and unsuitability between the CE business strategy and the context can further exacerbate implementation barriers. In this sense, we found that in our study’s unsuccessful case, the company failed to align its business to the particularities of the markets where it operated. Contrary, successful initiatives adopted strategies that incorporated contextual attributes in their business models, such as available infrastructure, current regulations, or consumer characteristics. Our results provide lessons from both failing and successful CE initiatives implemented by SMEs in an emerging economy. This work intends to help practitioners, policymakers, and researchers to create the required enabling conditions to accelerate the transition toward a CE in these regions.


2021 ◽  
Vol 11 (8) ◽  
pp. 3335
Author(s):  
Wen-Kuo Chen ◽  
Venkateswarlu Nalluri ◽  
Hsing-Chun Hung ◽  
Ming-Cheng Chang ◽  
Ching-Torng Lin

Continuous improvement and innovation are solid foundations for the textile sector to maintain excellent growth and active sustainability. As the limited resources possessed by textile companies generally result in the incapability of implementing circular economy (CE) strategies simultaneously, recently, researchers advocate that organizations should analyze the influential inter-relationship between key barriers to explore the more dominant determinants for designing improved actions for implementing CE in the textile sector. CE implementation in the textile sector appears to be in its infancy. Although much attention has been paid to CE implementation barriers, the present study tries to fill this research gap by analyzing the causal relationships among the CE barriers in the textile sector. Therefore, the twelve barriers are identified by an extensive literature review, and the application of the Fuzzy Delphi Method (FDM) based on the expert options from the textile sector. Subsequently, the causal inter-relationship among the key CE barriers is based on expert opinions using the decision-making trial and evaluation laboratory (DEMATEL). The results of this study indicate that three key barriers require quick action: “consumers lack knowledge and awareness about reused/recycle (B1)”, “lack of successful business models and frameworks to implement CE (B3)”, and “lack of an information exchange system between different stakeholders (B8)”. In addition, the results provide significant managerial implications, including implementations of CE in the textile sector. Not only should the government build regulations and friendly laws and encourage environmentally-friendly materials but the textile companies should also focus or monitor the recycling methods and quality to overcome the CE implementation issues. In addition, this study contributes to the textile sector transition toward CE by using the novel methodology for determining and prioritizing the key barriers. Finally, this work would help top management and the practitioners to better design effective infrastructural strategies for the textile sector transition towards CE.


Author(s):  
Tamara Merkulova ◽  
Kateryna Kononova ◽  
Olena Titomir

Author(s):  
Susan EVANS

This case study explores the strategic business opportunities, for Lane Crawford, an iconic luxury department store, to transition in a circular economy towards sustainability. A new experimentation framework was developed and conducted among cross departmental employees, during a Design Lab, with intention to co-create novel Circular Economy business concepts towards a new vision: the later was a reframe of the old system based on the principles of sustainability; to move beyond a linear operational model towards a circular economy that can contribute to a regenerative society. This work draws on both academic and professional experience and was conducted through professional practice. It was found that innovative co-created concepts, output from the Design Lab, can create radical change in a circular economy that is holistically beneficial and financially viable; looking forward to extract greater value a)Internal organization requires remodeling to transform towards a circular economy; b)Requirement for more horizonal teams across departments vs solely vertical; c)New language and relationships are required to be able to transition towards a circular economy; d)Some form of physical and virtual space requirements, for cross-disciplinary teams to come together to co-create; e)Ability to iterate, learn and evolve requires agency across the business


2020 ◽  
Vol 19 (4) ◽  
pp. 598-617 ◽  
Author(s):  
S.V. Ratner

Subject. The article considers the concept of circular economy, which has originated relatively recently in the academic literature, and is now increasingly recognized in many countries at the national level. In the European Union, the transition to circular economy is viewed as an opportunity to improve competitiveness of the European Union, protect businesses from resource shortages and fluctuating prices for raw materials and supplies, and a way to increase employment and innovation. Objectives. The aim of the study is to analyze the incentives developed by the European Commission for moving to circular economy, and to assess their effectiveness on the basis of statistical analysis. Methods. I employ general scientific methods of research. Results. The analysis of the EU Action Plan for the Circular Economy enabled to conclude that the results of the recent research in circular economy barriers, eco-innovation, technology and infrastructure were successfully integrated into the framework of this document. Understanding the root causes holding back the circular economy development and the balanced combination of economic and administrative incentives strengthened the Action Plan, and it contributed to the circular economy development in the EU. Conclusions. The measures to stimulate the development of the circular economy proposed in the European Action Plan can be viewed as a prototype for designing similar strategies in other countries, including Russia. Meanwhile, a more detailed analysis of barriers to the circular economy at the level of individual countries and regions is needed.


Author(s):  
Amit B Patil ◽  
Bharath Kumar B ◽  
Ajay P Karnalli

Technology Transfer (TT) is vital action from drug development in Research and Development (R and D) Department to commercial manufacturing till the product discontinuation. This review is an attempt to give an insight about the transfer of pharmaceutical product from R and D to production including necessary documents required to review the supporting documents and execution procedures in production shop floor. TT is considered effective, if there is a documented evidence that the process and its parameters, repeatedly results in desired product quality which was established upon during TT between the transferee and transferor. For the execution of TT process, expertise from different department such as Engineering, R and D, QA, process analyst and production are teamed. the transmission comprises of arrangements procured in these flows of improvement to achieve the quality as planned throughout manufacture.


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