Triggered release of anticancer drugs from PEGylated polydopamine nanospheres by near-infrared light

2015 ◽  
Vol 213 ◽  
pp. e122
Author(s):  
Xinyu Wang ◽  
Qiang Zhang ◽  
Yiyun Cheng
2013 ◽  
Vol 26 (15) ◽  
pp. 2424-2430 ◽  
Author(s):  
Li Zhou ◽  
Zhaowei Chen ◽  
Kai Dong ◽  
Meili Yin ◽  
Jinsong Ren ◽  
...  

2017 ◽  
Vol 61 ◽  
pp. 54-65 ◽  
Author(s):  
Francisco Martín-Saavedra ◽  
Eduardo Ruiz-Hernández ◽  
Clara Escudero-Duch ◽  
Martín Prieto ◽  
Manuel Arruebo ◽  
...  

Nanomedicine ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. 1579-1590 ◽  
Author(s):  
Christopher B Highley ◽  
Miju Kim ◽  
Daeyeon Lee ◽  
Jason A Burdick

2020 ◽  
Vol 59 (22) ◽  
pp. 8608-8615 ◽  
Author(s):  
Hejian Xiong ◽  
Xiuying Li ◽  
Peiyuan Kang ◽  
John Perish ◽  
Frederik Neuhaus ◽  
...  

2020 ◽  
Vol 132 (22) ◽  
pp. 8686-8693
Author(s):  
Hejian Xiong ◽  
Xiuying Li ◽  
Peiyuan Kang ◽  
John Perish ◽  
Frederik Neuhaus ◽  
...  

2020 ◽  
Vol 16 (9) ◽  
pp. 1381-1393
Author(s):  
Yuan Peng ◽  
Zhenwei Su ◽  
Xin Wang ◽  
Teng Wu ◽  
Hong Xiao ◽  
...  

Chemotherapy of hepatocellular carcinoma (HCC) is facing drug resistance, which leads to unsatisfactory therapeutic effect. Thus, a combination therapy using multiple drugs may overcome this challenge. The current study aims to realize a synergistic chemotherapy of HCC by using a near-infrared light (NIR) responsive nanocarrier to co-deliver the chemotherapeutic drug Doxorubicin (DOX) and molecular targeting agent Sorafenib (SF). The nanocarrier, which could effectively load DOX in its aqueous core while SF and IR-780 in its lipid bilayer, is fabricated from a temperature-sensitive liposome (TSL) modified with PF127. An efficient SF and DOX co-loading was achieved, and meanwhile the effective photothermal conversion of IR-780 under NIR laser may cause a disassembly of the liposome structure which may trigger a rapid drug release in tumor site, greatly boosting the synergetic chemotherapeutic effect. The NIR laser-triggered drug release and the synergistic anti-tumor effect were evaluated both in cell and animal experiments, which revealed that the PF127-modified TSL is a potent nanoplatform to improve the HCC treatment through co-delivering a drug combination.


2016 ◽  
Vol 52 (100) ◽  
pp. 14384-14387 ◽  
Author(s):  
Wei Ha ◽  
Xiao-Bo Zhao ◽  
Kan Jiang ◽  
Yang Kang ◽  
Juan Chen ◽  
...  

A graphene oxide hybrid supramolecular hydrogel with a well-defined interior microstructure was developed for near infrared light-triggered cascade release of two anticancer drugs.


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