Immobilizing Chitosan Nanoparticles in Polysulfone Ultrafiltration Hollow Fibre Membranes for Improving Uremic Toxins Removal

2021 ◽  
pp. 106878
Author(s):  
Muhamad Zulhilmi Zailani ◽  
Ahmad Fauzi Ismail ◽  
Goh Pei Sean ◽  
Siti Hamimah Sheikh Abdul Kadir ◽  
Mohd Hafiz Dzarfan Othman ◽  
...  
Keyword(s):  
Chitosan Nanoparticles ◽  
Hollow Fibre ◽  
Uremic Toxins

Enhanced adsorption and biocompatibility of polysulfone hollow fibre membrane via the addition of silica/alpha-mangostin hybrid nanoparticle for uremic toxins removal

2021 ◽  
pp. 106141
Author(s):  
Sumarni Mansur ◽  
Mohd Hafiz Dzarfan Othman ◽  
Muhammad Nidzhom Zainol Abidin ◽  
A.F. Ismail ◽  
Siti Hamimah Sheikh Abdul Kadir ◽  
...  
Keyword(s):  
Hollow Fibre ◽  
Uremic Toxins ◽  
Hollow Fibre Membrane ◽  
Fibre Membrane ◽  
Hybrid Nanoparticle ◽  
Enhanced Adsorption

Uremic toxins

1970 ◽  
Vol 126 (5) ◽  
pp. 843-845 ◽  
Author(s):  
P. L. Balestri
Keyword(s):  
Uremic Toxins

Uremic toxins and platelet function

1970 ◽  
Vol 126 (5) ◽  
pp. 823-826 ◽  
Author(s):  
H. I. Horowitz
Keyword(s):  
Platelet Function ◽  
Uremic Toxins

Optimization and Physicochemical Characterization of Chitosan and Chitosan Nanoparticles Extracted from the Crayfish Procambarus clarkii Wastes

2019 ◽  
Vol 38 (2) ◽  
pp. 385 ◽  
Author(s):  
Marwa M. El-Naggar ◽  
Wael S. I. Abou-Elmagd ◽  
Ashraf Suloma ◽  
Hamza A. El-Shabaka ◽  
Magdy T. Khalil ◽  
...  
Keyword(s):  
Procambarus Clarkii ◽  
Chitosan Nanoparticles ◽  
Physicochemical Characterization

Formulation of Modified Release Atorvastatin Nanoparticles by Emulsion Interfacial Reaction Method

2015 ◽  
Vol 8 (3) ◽  
pp. 2937-2940
Author(s):  
Sudhakar Sekar ◽  
Shee Sim May
Keyword(s):  
Interfacial Reaction ◽  
Therapeutic Potential ◽  
Chitosan Nanoparticles ◽  
In Vitro Release ◽  
Morphological Characteristics ◽  
Preparation Technique ◽  
Modified Release ◽  
Reaction Method ◽  
Vitro Release

The aim of the study is to formulate a modified release chitosan nanoparticles for the oral delivery of atorvastatin and to study the in vitro release of atorvastatin from chitosan nanoparticles. Atorvastatin-loaded chitosan nanoparticles were prepared with different concentration of cross-linking agent (glutaraldehyde) by emulsion interfacial reaction method. The formed nanoparticles were characterized in terms of size and morphological characteristics by scanning electron microscopy (SEM) and transmission electron microscope (TEM). Spherical and regular nanoparticles with the size range of 100-250nm were formed. Atorvastatin encapsulation efficiency of nanoparticles was found to be highest in ANP3, followed by ANP2 and ANP1. The in vitro release of atorvastatin was studied by membrane diffusion technique. The resulted cumulative percentage of drug released for ANP1, ANP2 and ANP3 were 60.08%, 34.81% and 20.39% respectively. Through this study, the nanoparticles preparation technique has shown to be a promising approach for enhancing the dissolution of hydrophobic drugs like atorvastatin calcium. The application of this novel delivery system offers good therapeutic potential in the management of hypercholesterolemia and dyslipidemia.

Amoxicilin and Clavulanic Acid Intercaled Nanostructures for Dentistry Uses

2019 ◽  
Vol 56 (2) ◽  
pp. 396-398
Author(s):  
Georgeta Zegan ◽  
Daniela Anistoroaei ◽  
Elena Mihaela Carausu ◽  
Eduard Radu Cernei ◽  
loredana Golovcencu
Keyword(s):  
Drug Delivery ◽  
Clavulanic Acid ◽  
Bacterial Infections ◽  
Drug Delivery Systems ◽  
Intracellular Transport ◽  
Oral Treatment ◽  
Chitosan Nanoparticles ◽  
Well Being ◽  
Cell Penetrating ◽  
Novel Drug

Amoxicillin and clavulanic acid are two of the most commonly prescribed antibacterial worldwide for treating oral infectious diseases. Oral health is of big importance for well-being and general health. A few novel drug delivery systems were designed for oral treatment and prophylaxis of different diseases in the oral cavity. This work focused on the latest drug delivery development of the most common oral pathologies, namely, periodontitis, oral mucosal infections, dental caries and oral cancer. Herein we reveal the synthesis, characterization and application of chitosan nanoparticles for intracellular transport of the weakly cell-penetrating amoxicillin and clavulanic acid in order to improve their efficacy on bacterial infections.

Adsorption-Based Strategies for Removing Uremic Toxins from Blood

2020 ◽  
Author(s):  
Yuhao Ma ◽  
Shuhui Li ◽  
Marcello Tonelli ◽  
Larry Unsworth
Keyword(s):  
Uremic Toxins
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