Electrochemical biosensor for telomerase activity assay based on HCR and dual interaction of the poly-adenine DNA with Au electrode and Ce-Ti dioxide nanorods

2020 ◽  
Vol 877 ◽  
pp. 114633
Author(s):  
Yi Wang ◽  
Yuan-Jun Cai ◽  
Ru-Ping Liang ◽  
Jian-Ding Qiu
Keyword(s):  
Electrochemical Biosensor ◽  
Telomerase Activity ◽  
Activity Assay ◽  
Au Electrode

A dual-functional electrochemical biosensor for the detection of prostate specific antigen and telomerase activity

2013 ◽  
Vol 49 (59) ◽  
pp. 6602 ◽  
Author(s):  
Jing Liu ◽  
Cai-Yu Lu ◽  
Hong Zhou ◽  
Jing-Juan Xu ◽  
Zong-Hua Wang ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Electrochemical Biosensor ◽  
Specific Antigen ◽  
Telomerase Activity ◽  
Dual Functional

An electrochemical biosensor for the activity assay of polynucleotide kinase and inhibitor screening

2015 ◽  
Vol 7 (23) ◽  
pp. 9984-9991 ◽  
Author(s):  
Qingming Zhang ◽  
Xue Li ◽  
Bingchen Li ◽  
Huanshun Yin ◽  
Shiyun Ai
Keyword(s):  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Activity Assay ◽  
Inhibitor Screening ◽  
Polynucleotide Kinase

A sensitive and selective electrochemical biosensor was fabricated for polynucleotide kinase (PNK) activity assay and inhibitor screening based on phos-tag-biotin mediated double signal amplification.

scholarly journals A Highly Sensitive Telomerase Activity Assay that Eliminates False-Negative Results Caused by PCR Inhibitors

Molecules ◽  
2013 ◽  
Vol 18 (10) ◽  
pp. 11751-11767 ◽  
Author(s):  
Hidenobu Yaku ◽  
Takashi Murashima ◽  
Daisuke Miyoshi ◽  
Naoki Sugimoto
Keyword(s):  
False Negative ◽  
Telomerase Activity ◽  
Activity Assay ◽  
Pcr Inhibitors ◽  
Negative Results ◽  
False Negative Results ◽  
Highly Sensitive

Multi-code magnetic beads based on DNAzyme-mediated double-cycling amplification for a point-of-care assay of telomerase activity

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4241-4249 ◽  
Author(s):  
Chunxue Liu ◽  
Susu Zhang ◽  
Xia Li ◽  
Qingwang Xue ◽  
Wei Jiang
Keyword(s):  
Medical Care ◽  
Magnetic Beads ◽  
Point Of Care ◽  
High Specificity ◽  
Telomerase Activity ◽  
Activity Assay ◽  
Double Cycling ◽  
Specificity And Sensitivity ◽  
Point Of Care Assay

Development of a reliable and facile telomerase activity assay with high specificity and sensitivity is a central challenge to make telomerase testing a routine part of medical care with respect to cancer.

Label-free Electrochemical Biosensor Based on Graphene/Ionic Liquid Nanocomposite for the Detection of Organophosphate Pesticides

2011 ◽  
Vol 1283 ◽  
Author(s):  
Tae Jung Park ◽  
MinHo Yang ◽  
Bong Gill Choi ◽  
Nam Su Heo ◽  
Seok Jae Lee ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Graphene Oxide ◽  
High Performance ◽  
Electrochemical Biosensor ◽  
Modified Electrodes ◽  
Organophosphorus Hydrolase ◽  
Organophosphate Pesticides ◽  
Label Free ◽  
Au Electrode ◽  
Reduced Graphene

ABSTRACTThe advanced electrodes for detecting organophosphate pesticides were prepared by modification of the gold (Au) electrode with the reduced graphene oxide/ionic liquid (RGO/IL) nanohybrids. Due to the cationic and anionic parts, the ILs on RGO sheets provide the amount of functional groups for dispersion of hybrids and immobilization of organophosphorus hydrolase (OPH) enzymes. After the immobilization of OPH on the RGO/IL-modified Au electrodes, the modified electrodes represent faster electron transfer than that of Au electrode, resulting in high performance of biosensor with response time (~ 10 s) and sensitivity (4.56 nA μM−1). In addition, the OPH/RGO/IL-modified Au electrode displayed good stability and reproducibility.

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