Topical anti-inflammatory, gastroprotective and antioxidant effects of the essential oil of Lippia sidoides Cham. leaves

2007 ◽  
Vol 111 (2) ◽  
pp. 378-382 ◽  
Author(s):  
Maria Vivina Barros Monteiro ◽  
Ana Karine Rocha de Melo Leite ◽  
Luciana Medeiros Bertini ◽  
Selene Maia de Morais ◽  
Diana Célia Sousa Nunes-Pinheiro
Keyword(s):  
Essential Oil ◽  
Lippia Sidoides ◽  
Anti Inflammatory ◽  
Antioxidant Effects

Skład chemiczny i właściwości biologiczne Geum urbanum L. – aktualny stan badań

2019 ◽  
Vol 20 (3) ◽  
Author(s):  
Izabela Czapska-Pietrzak ◽  
Elżbieta Studzińska-Sroka ◽  
Wiesława Bylka
Keyword(s):  
Essential Oil ◽  
Folk Medicine ◽  
Perennial Herb ◽  
Liver Disorders ◽  
Rosaceae Family ◽  
Anti Inflammatory ◽  
Antioxidant Effects ◽  
Geum Urbanum

Geum urbanum L. (St. Benedict’s herb, Wood Avens) belonging to Rosaceae family, is a perennial herb occuring in the moderate zone of both Hemispheres. The roots and rhizomes containing: tannins, especially ellagitannins (mainly gemin), essential oil (mainly gein), flavonoids, proanthocyanidins, triterpenes, carbohydrates. In folk medicine it was used in gastro-enteritis and liver disorders, and to induce cardiogenesis also externally for reducing the gingivitis. The results of experiments on: antimicrobial, anti-inflammatory, cardiogenic and antioxidant effects were presented.

scholarly journals The anti-inflammatory and antioxidant effects of rosa damascena mill. essential oil on the lung injury in the CLP model

2020 ◽  
Vol 19 (74) ◽  
pp. 277-294
Author(s):  
Abolfazl Dadkhah ◽  
Faezeh Fatemi ◽  
Mohammad Reza Mohammadi Malayeri ◽  
Mohammad Hassan Karvin Ashtiani ◽  
Zahra Mosavi ◽  
...  
Keyword(s):  
Essential Oil ◽  
Lung Injury ◽  
Rosa Damascena ◽  
Anti Inflammatory ◽  
Antioxidant Effects

Antifungal and anti-inflammatory claims for wild carrot essential oil

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
J Valente ◽  
R Resende ◽  
M Zuzarte ◽  
MJ Gonçalves ◽  
MC Lopes ◽  
...  
Keyword(s):  
Essential Oil ◽  
Wild Carrot ◽  
Anti Inflammatory

Comparative Analysis of In-Vitro Biological Activities of Methyl Eugenol Rich Cymbopogon khasianus Hack., Leaf Essential Oil with Pure Methyl Eugenol Compound

2020 ◽  
Vol 21 (10) ◽  
pp. 927-938 ◽  
Author(s):  
Roktim Gogoi ◽  
Rikraj Loying ◽  
Neelav Sarma ◽  
Twahira Begum ◽  
Sudin K. Pandey ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Biological Activities ◽  
Methyl Eugenol ◽  
Dpph Assay ◽  
Pure Compound ◽  
Allium Cepa Assay ◽  
Anti Inflammatory ◽  
Lemongrass Essential Oil

Background: The essential oil of methyl eugenol rich Cymbopogon khasianus Hack. was evaluated and its bioactivities were compared with pure methyl eugenol. So far, methyl eugenol rich essential oil of lemongrass was not studied for any biological activities; hence, the present study was conducted. Objective: This study examined the chemical composition of essential oil of methyl eugenol rich Cymbopogon khasianus Hack., and evaluated its antioxidant, anti-inflammatory, antimicrobial, and herbicidal properties and genotoxicity, which were compared with pure compound, methyl eugenol. Material and Methods: Methyl eugenol rich variety of Cymbopogon khasianus Hack., with registration no. INGR18037 (c.v. Jor Lab L-9) was collected from experimental farm CSIR-NEIST, Jorhat, Assam (26.7378°N, 94.1570°E). The essential oil wasobtained by hydro-distillation using a Clevenger apparatus. The chemical composition of the essential oil was evaluated using GC/MS analysis and its antioxidant (DPPH assay, reducing power assay), anti-inflammatory (Egg albumin denaturation assay), and antimicrobial (Disc diffusion assay, MIC) properties, seed germination effect and genotoxicity (Allium cepa assay) were studied and compared with pure Methyl Eugenol compound (ME). Results: Major components detected in the Essential Oil (EO) through Gas chromatography/mass spectroscopy analysis were methyl eugenol (73.17%) and β-myrcene (8.58%). A total of 35components were detected with a total identified area percentage of 98.34%. DPPH assay revealed considerable antioxidant activity of methyl eugenol rich lemongrass essential oil (IC50= 2.263 μg/mL), which is lower than standard ascorbic acid (IC50 2.58 μg/mL), and higher than standard Methyl Eugenol (ME) (IC50 2.253 μg/mL). Methyl eugenol rich lemongrass EO showed IC50 38.00 μg/mL, ME 36.44 μg/mL, and sodium diclofenac 22.76 μg/mL, in in-vitro anti-inflammatory test. Moderate antimicrobial activity towards the 8 tested microbes was shown by methyl eugenol rich lemongrass essential oil whose effectiveness against the microbes was less as compared to pure ME standard. Seed germination assay further revealed the herbicidal properties of methyl eugenol rich essential oil. Moreover, Allium cepa assay revealed moderate genotoxicity of the essential oil. Conclusion: This paper compared the antioxidant, anti-inflammatory, antimicrobial, genotoxicity and herbicidal activities of methyl eugenol rich lemongrass with pure methyl eugenol. This methyl eugenol rich lemongrass variety can be used as an alternative of methyl eugenol pure compound. Hence, the essential oil of this variety has the potential of developing cost-effective, easily available antioxidative/ antimicrobial drugs but its use should be under the safety range of methyl eugenol and needs further clinical trials.

Assessment of Cota altissima (L.) J. Gay for phytochemical composition and antioxidant, anti-inflammatory, antidiabetic and antimicrobial activities

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Gamze Göger ◽  
Muhammed Allak ◽  
Ali Şen ◽  
Fatih Göger ◽  
Mehmet Tekin ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Essential Oil ◽  
Antioxidant Activities ◽  
Antimicrobial Activities ◽  
Antidiabetic Activity ◽  
Gram Negative Bacteria ◽  
Inhibitory Effects ◽  
Dicaffeoylquinic Acid ◽  
Anti Inflammatory ◽  
Phytochemical Profiles

Abstract Phytochemical profiles of essential oil (EO), fatty acids, and n-hexane (CAH), diethyl ether (CAD), ethyl acetate (CAE) and methanol extracts (CAM) of Cota altissima L. J. Gay (syn. Anthemis altissima L.) were investigated as well as their antioxidant, anti-inflammatory, antidiabetic and antimicrobial activites. The essential oil was characterized by the content of acetophenone (35.8%) and β-caryophyllene (10.3%) by GC-MS/FID. Linoleic and oleic acid were found as main fatty acids. The major constituents of the extracts were found to be 5-caffeoylquinic acid, 3,5-dicaffeoylquinic acid, isorhamnetin glucoside, quercetin and quercetin glucoside by LC-MS/MS. Antioxidant activities of the extracts were determined by scavenging of DPPH and ABTS free radicals. Also, the inhibitory effects on lipoxygenase and α-glucosidase enzymes were determined. Antimicrobial activity was evaluated against Gram positive, Gram negative bacteria and yeast pathogens. CAM showed the highest antioxidant activity against DPPH and ABTS radicals with IC50 values of 126.60 and 144.40 μg/mL, respectively. In the anti-inflammatory activity, CAE demonstrated the highest antilipoxygenase activity with an IC50 value of 105.40 μg/mL, whereas, CAD showed the best inhibition of α-glucosidase with an IC50 value of 396.40 μg/mL in the antidiabetic activity. CAH was effective against Staphylococcus aureus at MIC = 312.5 µg/mL. This is the first report on antidiabetic, anti-inflammatory and antimicrobial activities of different extracts of C. altissima.

scholarly journals Anti-Inflammatory and Antioxidant Effects of Dietary Supplementation and Lifestyle Factors

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 371
Author(s):  
Llion Arwyn Roberts ◽  
Katsuhiko Suzuki
Keyword(s):  
Dietary Supplementation ◽  
Lifestyle Factors ◽  
Anti Inflammatory ◽  
Antioxidant Effects

Trends relating to specific diets and lifestyle factors like physical (in) activity have formed in recent times [...]

scholarly journals Carbon Monoxide Therapy Using Hybrid Carbon Monoxide-Releasing/Nrf2-Inducing Molecules through a Neuroprotective Lens

Chemistry ◽  
2021 ◽  
Vol 3 (3) ◽  
pp. 800-817
Author(s):  
Flavia Cavicchioli ◽  
Izzy M. Cesarotti ◽  
Madison Fangman ◽  
Josh Lua ◽  
Raymond Hautamaki ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Multiple Forms ◽  
Therapy Development ◽  
Anti Inflammatory ◽  
New Applications ◽  
Therapeutic Compound ◽  
Antioxidant Effects ◽  
Hybrid Carbon

Carbon monoxide (CO) has long been known for its toxicity. However, in recent decades, new applications for CO as a therapeutic compound have been proposed, and multiple forms of CO therapy have since been developed and studied. Previous research has found that CO has a role as a gasotransmitter and promotes anti-inflammatory and antioxidant effects, making it an avenue of interest for medicine. Such effects are possible because of the Nrf2/HO1 pathway, which has become a target for therapy development because its activation also leads to CO release. Currently, different forms of treatment involving CO include inhaled CO (iCO), carbon monoxide-releasing molecules (CORMs), and hybrid carbon monoxide-releasing molecules (HYCOs). In this article, we review the progression of CO studies to develop possible therapies, the possible mechanisms involved in the effects of CO, and the current forms of therapy using CO.

Sign in / Sign up

Export Citation Format

Share Document