The use of comprehensive geriatric assessment in older patients before allologeneic hematopoietic stem cell transplantation: A cross-sectional study

ABSTRACT Objective: to identify the knowledge and ability of caregivers on hand hygiene in hematopoietic stem cell transplantation. Method: a prospective cross-sectional study. A questionnaire was used to identify the knowledge and it was observed the hygiene technique performance. Data were collected in two units (autologous and allogeneic transplant). Results: the 37 participants recognized the importance of hand hygiene and 95.5% related to removal of dirt or infection prevention. 91.9% stated that it was important to clean their hands with soap and water when entering and leaving the room, and 64.9% understood that it was necessary to apply alcoholic solution after washing. On average, the caregivers scored 6.16 steps, when demonstrating the washing technique and 3.91 steps in the friction with alcoholic solution. Conclusion: although they recognize the importance of the procedure, there are deficits related to the moment and the correct way of doing it, evidencing the need for strategies aimed at improving this process.

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Analysis of factors associated with patient-reported physical functioning scores at discharge of allogeneic hematopoietic stem cell transplantation patients: a cross-sectional study

Supportive Care in Cancer ◽

10.1007/s00520-021-06323-5 ◽

2021 ◽

Author(s):

Masanobu Murao ◽

Ryota Hamada ◽

Tadakazu Kondo ◽

Junsuke Miyasaka ◽

Michiko Yoshida ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Physical Functioning ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Hematopoietic Stem ◽

Factors Associated ◽

Patient Reported

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Pain, Fatigue, Nausea, and Vomiting as Predictors of Anxiety in Patients Undergoing Hematopoietic Stem Cell Transplantation: A Cross-sectional Study

10.21203/rs.3.rs-984888/v1 ◽

2021 ◽

Author(s):

Nilofar Pasyar ◽

Masoume Rambod ◽

Fatemeh Zahedi ◽

Mani Ramzi

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

State Anxiety ◽

Cross Sectional Study ◽

Nausea And Vomiting ◽

Sectional Study ◽

Cross Sectional ◽

Hematopoietic Stem ◽

Anxiety Levels

Abstract PurposeThe present study aimed to determine the predictive roles of pain, fatigue, nausea, and vomiting in anxiety among the patients undergoing Hematopoietic Stem Cell Transplantation (HSCT).MethodsThe present cross-sectional study was conducted on 200 patients treated by HSCT referred to the centers affiliated to Shiraz University of Medical Sciences, Iran. The data were collected using Spielberger Anxiety Questionnaire, Numerical Pain Scale, Brief Fatigue Inventory, and Rhodes Nausea and Vomiting Index. Then, the data were analyzed using Spearman’s test and multiple regression analysis.ResultsThe means of state anxiety, trait anxiety, pain, fatigue, and nausea, vomiting and retching were 41.67 (SD = 9.71), 43.78 (SD = 9.00), 3.79 (SD = 2.79), 4.23 (SD = 2.48), 6.31 (SD = 7.53), respectively. The results showed that the participants with higher pain and fatigue scores had higher anxiety levels. The individuals who had more nausea and vomiting had higher anxiety levels, as well. It indicated that fatigue, pain, amount of vomiting, and severity of nausea, vomiting and retching were the predictors of trait anxiety. This study showed the predictor role of pain, fatigue, and severity of retching in state anxiety. ConclusionThe study findings revealed an association between anxiety and pain, fatigue, nausea, and vomiting among the HSCT patients. The results also showed that fatigue and pain were the predictors of anxiety among the patients. Yet, future studies are recommended to determine the other factors contributing to anxiety among the HSCT patients.

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Review of Stem-Cell Transplantation for Myelodysplastic Syndromes in Older Patients in the Context of the Decision Memo for Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome Emanating From the Centers for Medicare and Medicaid Services

Journal of Clinical Oncology ◽

10.1200/jco.2010.32.1919 ◽

2011 ◽

Vol 29 (5) ◽

pp. 566-572 ◽

Cited By ~ 18

Author(s):

Sergio A. Giralt ◽

Mary Horowitz ◽

Daniel Weisdorf ◽

Corey Cutler

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Myelodysplastic Syndrome ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Myelodysplastic Syndromes ◽

Older Patients ◽

The United States ◽

Hematopoietic Stem

Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal hematopoietic stem-cell disorders that result in varying degrees of cytopenia and risk of transformation into acute leukemia. Allogeneic stem-cell transplantation (SCT) is the only known cure for this disease. The treatment is routinely used for younger patients, but only a minority of patients older than the age of 60 undergo this procedure. The overall MDS incidence is 3.3 per 100,000, but the incidence in patients older than age 70 is between 15 and 50 per 100,000. The median age at presentation is 76 years. Medicare-age patients 65 or older represent 80% of the total population receiving an MDS diagnosis. In the United States, one of the obstacles to SCT for older patients with MDS has been lack of third party reimbursement. On August 4, 2010, the Centers for Medicare and Medicaid Services released their Decision Memo for Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) for Myelodysplastic Syndrome. This memo states: “Allogeneic HSCT for MDS is covered by Medicare only for beneficiaries with MDS participating in an approved clinical study that meets the criteria below…. ” In this review, we will summarize what is known regarding the role of allogeneic SCT in older patients as well as other elements that should be included within clinical trials that can provide the evidence necessary to demonstrate that allogeneic SCT should be a covered benefit for Medicare beneficiaries.

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